Biosystematic Studies on the Genus Hemerocallis (Liliaceae) : II. Variation in Gross Morphology of the H. fulva Complex with Special Reference to the Identity of H. fulva v. longituba and v. disticha

Hemerocallis fulva sensu lato is known to be an exceedingly polymorphic species. In a recent taxonomic revision of the genus Hemerocallis in Japan and its neighbouring regions, Matsuoka and Hotta (1966) distinguished primarily by gross morphology, the following seven infraspecific taxa in the H. fulva complex: H. fulva L. v. fulva : v. Kwanso Regel ; v. sempervirP-ns (Araki) H. Hotta : v. littorea (Makino) M. Hotta ; v. longituba (Miq.) Maxim. ; v. disticha (Donn) M. Hotta ; and v. paucijlora M. Hotta & Matsuoka. However, there are still considerable discre· pancies in the taxonomic concept and treatment of this complex group. It has not been resolved, for example, whether or not several native Japanese taxa now referred to the H. fulva complex, such as v. disticha, v. longituba, etc. in the sense of Matsuoka and Hotta (1. c. ) should be referred to the same taxonomic group as the continental taxon, H. fulva v. fulva. This latter group also includes the double-flowered taxon, v. Kwanso which is widely distributed over the Japanese Islands excepting northern Hokkaido (cf. Ohwi, 1953, 1965; Kitamura et al., 1967).This paper particularly attempts to draw attention to the taxonomical identity of two native Japanese taxa, H. fulva v. longituba and v. disticha. In the present study; the variabilities of the plants, referred to the following four taxa of this complex, i. e., v. fulva, v. Kwanso, v. disticha, and v. longituba, are analyzed and compared, and their taxonomic status briefly discussed

Biosystematic Studies on the genus Hemerocallis (Liliaceae) : I. Introgressive Hybridization between H. citrina v. vespertina and H. fulva sensu lato

The occurrence of a natural hybrid swarm between Hemerocallis citrina v. vespertina (Hara) M. Hotta and two varieties of H. fulva, i. e. , v. longituba (Miq.) Maxim. and v. disticha (Donn) M. Hotta, was first reported by Nakao and Yamashita (1956) from Matsunoki, located at the distance of 4 km east of Takayama City, Gifu Prefecture, Central Honshu.Based on the results of their investigation, it was concluded that this particular hybrid swarm found in a valley near Takayama represents an initial stage of introgression of genes of H. citrina v. vespertina into the population of H. fulva (Nakao and Yamashita, l. c. ) . Another example of introgressive hybridization in Hemerocallis, i. e., between H. middendorffii and H. yezoensis was reported by Kawano (1961) from Otanoshike near Kushiro City in Hokkaido. In both cases, the ecological disturbance of the habitats was deemed to be the maj or causes in breaking down the isolation barrier previously existing between these plants.In the present study, a natural hybrid population of Hemerocallis in the Matsunoki district was re-investigated from several new standpoints in order to know more precisely about the biological status of this particular population. In addition to the analyses of gross morphology and ecology, the karyotypes and meiotic behaviours of the chromosomes were studied. The pollen fertility, the setting rate and germination rate of the seeds were also examined. Furthermore, the electrophoretic banding patterns of acid-soluble protein extracted from the rhizomes of both parental and hybrid plants were likewise analyzed and compared with one another

A structure theory of automata characterized by groups

The structure of a strongly connected permutation automaton, a quasiperfect automaton, and a perfect automaton are discussed algebraically using group theory. A characterization theorem for the three classes of automata, a condition for direct product decomposability of a strongly connected permutation automaton, and some other related results are proposed in this paper

The effects of switching daily teriparatide to oral bisphosphonates or denosumab in patients with primary osteoporosis

The aim of this 12-month, observational study was to compare the effects of switching daily teriparatide (TPTD) to oral bisphosphonates (BP) therapy or denosumab (DMAb) therapy in patients with primary osteoporosis. Patients [n = 78; 71 postmenopausal women and seven men; mean age 76.3 (64–94) years; mean duration of prior daily TPTD therapy 20.1 (6–24) months] were allocated to either the (1) “switch-to-BP” group [n = 36; weekly alendronate 35 mg (n = 19), weekly risedronate 17.5 mg (n = 12), monthly minodronate 50 mg (n = 5)]; or (2) “switch-to-DMAb” group (n = 42; 60 mg sc every 6 months) based on each physicians’ decision. Changes in bone mineral density (BMD) and serum bone turnover markers were monitored every 6 months. No significant difference was observed in baseline clinical characteristics between the groups. After 12 months, the increase in BMD was significantly greater in the switch-to-DMAb group compared to the switch-to-BP group: lumbar spine (6.2 vs. 2.6 %; P < 0.01), total hip (4.2 vs. 1.1 %; P < 0.05), and femoral neck (3.5 vs. 1.4 %; P < 0.05). In addition, the patients in the switch-to-DMAb group showed a significant decrease compared to those in the switch-to-BP group in TRACP-5b (−55.8 vs. −32.8 %; P < 0.01) and ucOC (−85.5 vs. −65.0 %; P < 0.001), while no significant difference was observed in PINP (−67.5 vs. −62.1 %). Switching daily TPTD to DMAb significantly increased BMD and decreased bone resorption marker compared to switching to oral BP at 12 months, and thus may provide an effective sequential treatment option after daily TPTD treatment.This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00774-015-0731-xEbina K., Hashimoto J., Kashii M., et al. The effects of switching daily teriparatide to oral bisphosphonates or denosumab in patients with primary osteoporosis. Journal of Bone and Mineral Metabolism 35, 91 (2017); https://doi.org/10.1007/s00774-015-0731-x

Topkapı Sarayı Müzesinde Türk saatleri

Taha Toros Arşivi, Dosya No: 114-Müzelerİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

World Robot Challenge 2020 -- Partner Robot: A Data-Driven Approach for Room Tidying with Mobile Manipulator

Tidying up a household environment using a mobile manipulator poses various challenges in robotics, such as adaptation to large real-world environmental variations, and safe and robust deployment in the presence of humans.The Partner Robot Challenge in World Robot Challenge (WRC) 2020, a global competition held in September 2021, benchmarked tidying tasks in the real home environments, and importantly, tested for full system performances.For this challenge, we developed an entire household service robot system, which leverages a data-driven approach to adapt to numerous edge cases that occur during the execution, instead of classical manual pre-programmed solutions. In this paper, we describe the core ingredients of the proposed robot system, including visual recognition, object manipulation, and motion planning. Our robot system won the second prize, verifying the effectiveness and potential of data-driven robot systems for mobile manipulation in home environments

Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice

A close correlation between atherosclerosis, inflammation, and osteoporosis has been recognized, although the precise mechanism remains unclear. The growth factor progranulin (PGRN) is expressed in various cells such as macrophages, leukocytes, and chondrocytes. PGRN plays critical roles in a variety of diseases, such as atherosclerosis and arthritis by inhibiting Tumor Necrosis Factor-α (TNF-α) signaling. The purpose of this study was to investigate the effect of PGRN on bone metabolism. Forty-eight-week old female homozygous PGRN knockout mice (PGRN-KO) (n = 8) demonstrated severe low bone mass in the distal femur compared to age- and sex-matched wild type C57BL/6J mice (WT) (n = 8) [BV/TV (%): 5.8 vs. 16.6; p < 0.001, trabecular number (1/mm): 1.6 vs. 3.8; p < 0.001]. In vitro, PGRN inhibited TNF-α-induced osteoclastogenesis from spleen cells of PGRN-KO mice. Moreover, PGRN significantly promoted ALP activity, osteoblast-related mRNA (ALP, osteocalcin) expression in a dose-dependent manner and up-regulated osteoblastic differentiation by down-regulating phosphorylation of ERK1/2 in mouse calvarial cells. In conclusion, PGRN may be a promising treatment target for both atherosclerosis and inflammation-related osteoporosis.Noguchi T., Ebina K., Hirao M., et al. Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice. Biochemical and Biophysical Research Communications 465, 638 (2015); https://doi.org/10.1016/j.bbrc.2015.08.077