Design basis for Arctic infrastructure facilities

A discussion related to the selection of a proper design basis for Arctic infrastructure facilities is presented. The design basis, which must be sufficiently robust to ensure safe operations of the facilities during their planned lifetime, should include relevant information available from the local and indigenous people of the area. The need to properly document all data and assumptions made when preparing the design basis is highlighted, and it is emphasized that, in the case of the upgrading of the facilities, all new data collected must be included in the database. Documentation of all updating is necessary and must be available to all involved during maintenance activities and for possible later upgrading of the facilities. This database must be available digitally, as access to the basics for the design may be of particular concern in the sparsely populated Arctic region, where the distribution of paper copies takes a long time, particularly in the case of emergency situations. Therefore, this database must be protected from cyberattacks. A "Plan B" is needed to ensure that a backup of the fully updated design basis documents, as well as documentation of the "as built" facilities, is available at any time

AORTIC DISSECTION IN THE ELDERLY: COMPARING SEPTUAGENARIANS AND OCTOGENARIANS

none15siopenJabara, Justin; Peterson, Mark; Trimarchi, Santi; Myrmel, Truls; Reece, T. Brett; Bossone, Eduardo; Hutchison, Stuart; Gilon, Dan; Appoo, Jehangir; Di Eusanio, Marco; Montgomery, Daniel; Isselbacher, Eric; Nienaber, Christoph; Eagle, Kim; Patel, HimanshuJabara, Justin; Peterson, Mark; Trimarchi, Santi; Myrmel, Truls; Reece, T. Brett; Bossone, Eduardo; Hutchison, Stuart; Gilon, Dan; Appoo, Jehangir; Di Eusanio, Marco; Montgomery, Daniel; Isselbacher, Eric; Nienaber, Christoph; Eagle, Kim; Patel, Himansh

Acute type A aortic dissection in the elderly: clinical characteristics, management, and outcomes in the current era

n/

Making waves: collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making

The presence of SARS-CoV-2 RNA in wastewater was first reported in March 2020. Over the subsequent months, the potential for wastewater surveillance to contribute to COVID-19 mitigation programmes has been the focus of intense national and international research activities, gaining the attention of policy makers and the public. As a new application of an established methodology, focused collaboration between public health practitioners and wastewater researchers is essential to developing a common understanding on how, when and where the outputs of this non-invasive community-level approach can deliver actionable outcomes for public health authorities. Within this context, the NORMAN SCORE "SARS-CoV-2 in sewage" database provides a platform for rapid, open access data sharing, validated by the uploading of 276 data sets from nine countries to-date. Through offering direct access to underpinning meta-data sets (and describing its use in data interpretation), the NORMAN SCORE database is a resource for the development of recommendations on minimum data requirements for wastewater pathogen surveillance. It is also a tool to engage public health practitioners in discussions on use of the approach, providing an opportunity to build mutual understanding of the demand and supply for data and facilitate the translation of this promising research application into public health practice. [Abstract copyright: Copyright © 2021 Elsevier Ltd. All rights reserved.