Guida alla flora delle Alpi Carniche meridionali (Ampezzo - Sauris)

This book is a guide to the vascular plants occurring in the sector of the southern Carnic Alps (NE Italy) that stretches from Ampezzo to Sauris (Province of Udine), plus the adjoining area in the Province of Belluno which includes M. Bivera, M. Tiarfin and the subalpine meadows around Casera Razzo (1244 infrageneric taxa). The general introduction is followed by an original dichotomous key produced using software FRIDA, illustrated by photographs and ecological-biogeographical notes for all species. The appendix contains some elementary notions of Botany and an index of the scientific names associated with those of the respective families.Il volume è una guida alle piante vascolari sinora note per il settore delle Alpi Carniche meridionali che si estende da Ampezzo alla Conca di Sauris (UD), comprendendo anche un’area in provincia di Belluno che include il M. Bivera, il M. Tiarfin e i pascoli subalpini nei dintorni di Casera Razzo (1244 tra specie e sottospecie). L’introduzione generale è seguita da una chiave dicotomica originale, prodotta utilizzando il programma FRIDA, illustrata da fotografie e note ecologico-biogeografiche per tutte le specie. L’appendice contiene alcune nozioni di botanica elementare e l’indice dei nomi scientifici delle piante associati a quelli delle rispettive famiglie

I licheni epifiti del Parco Naturale di Paneveggio-Pale di San Martino

Da molti anni, nel Parco di Paneveggio-Pale di San Martino sono in corso ricerche sui licheni che hanno permesso di realizzare un inventario delle specie e di apportare contributi originali alle conoscenze sulla loro ecologia. Il Parco di Paneveggio ha una missione molto importante nella conservazione dei licheni: nel suo territorio ne sono noti quasi 650, pari al 50% dei licheni del Trentino-Alto Adige, che è la regione italiana con il maggior numero di specie note. Tuttavia, una stima realistica della biodiversità lichenica del Parco potrebbe essere di circa 900 specie! Il Parco ha commissionato al Dipartimento di Scienze della Vita dell'Università di Trieste la realizzazione di una guida interattiva ai licheni epifiti, che al momento include 242 specie e che è consultabile in rete dal sito del Parco o da quello del progetto Dryades (www.dryades.eu). L'identificazione dei macrolicheni (licheni fruticosi, fogliosi e squamulosi) può essere effettuata anche senza l'uso del microscopio,ed è quindi più facile. Al contrario, per l'identificazione dei licheni crostosi è spesso indispensabile osservare caratteri anatomici al microscopio, soprattuto quelli relativi alle spore

Methylene blue MMX® tablets for chromoendoscopy. Bioavailability, colon staining and safety in healthy volunteers undergoing a full colonoscopy.

Abstract Methylene blue-MMX® tablets are proposed as an aid for detection and visualisation of adenomas and carcinomas in patients undergoing colonoscopy, by improving their detection rate and highlighting the presence of the intestinal dysplastic lesions. Single total doses of 100 and 200 mg were administered to healthy volunteers undergoing a bowel cleansing preparation and a full colonoscopy to investigate the colonic staining. The pharmacokinetics of methylene blue and the safety after exposure to the tablets were also investigated. With 200 mg, the best staining, assessed as the sum of acceptable and good staining, was achieved in the ascending colon and rectosigmoid (75% subjects each), the transverse and the descending colon (approximately 63% each). Absence of staining or overstaining were reported for no colonic region of interest in any subject. Similar results were observed in the 100 mg dose group. Methylene blue blood concentrations reached a peak (Cmax) in a median time (Tmax) of 12 h with 100 mg and 16 h with 200 mg. AUC0-t was 10.7 ± 6.7 μg/mLxh after 100 mg and 25.2 ± 7.4 μg/mLxh after 200 mg. Half-life ranged between 9 and 22 h after the lower dose and between 6 and 26 h after the higher dose. The cumulative urinary excretion was about 28% after 100 mg and about 39% after 200 mg up to 60 h post-dose. The overall frequency of adverse events after single dose of the test product administered along with a bowel cleansing preparation was 39%, but only one was related to the test product: abnormal transaminases. The most frequent adverse event was a transient polyuria (17%). One serious adverse event (gastrointestinal haemorrhage) led the subject to study discontinuation and hospitalisation and another subject withdrew the study due to one adverse event (haematemesis). Either event was not related to methylene blue

Treatment of Solitary Painful Osseous Metastases with Radiotherapy, Cryoablation or Combined Therapy: Propensity Matching Analysis in 175 Patients

aim of this study was to identify outcomes in pain relief and quality of life in patients with a solitary painful osseous metastasis treated by radiotherapy, cryoablation or the combination using a propensity score matching study design

Symmetries and criticality of generalised van der Waals models

We consider a family of thermodynamic models such that the energy density can be expressed as an asymptotic expansion in the scale formal parameter and whose terms are suitable functions of the volume density. We examine the possibility to construct solutions for the Maxwell thermodynamic relations relying on their symmetry properties and deduce the critical properties implied in terms of the the dynamics of coexistence curves in the space of thermodynamic variables

Genetic and environmental effects on a meat spotting defect in seasoned dry-cured ham

Purpose of this investigation was to determine the nature of a visible spotting defect on the slice of dry-cured ham and assess environmental and genetic causes of this frequent problem. A group of 233 pigs from commercial cross-breeding lines, progeny of ten boars and forty seven sows, was raised in a single herd to obtain the “Italian Heavy Pig”, typically slaughtered at 160 ± 10 kg live weight and older than 9 months of age. A quality evaluation of their right dry-cured hams, seasoned according to the Parma P.D.O. protocol, was undertaken. Each ham was cross-sectioned to obtain a slice of Semimembranosus, Semitendinosus and Biceps Femoris muscles. The focused phenotype was the presence/absence of brownish spots in these muscles, which represent a remarkable meat defect with strong impact on the final sale price. Environmental and management factors were considered in order to evaluate variability related to the phenotype. Animals were raised on two different flooring types (concrete and slatted floor) and a Vitamin C diet was also supplemented in the last 45 days before slaughtering to half of the animals. While the pre-planned environmental effects did not show any significant contribution to the total variability of the phenotype, the genetic analysis showed a near to zero value for heritability with a consistent 0.32 repeatability. The proportion of the total phenotypic variance was explained by an important dominance genetic component (0.26) indicating that the technological seasoning process may play a secondary role on the expression of this phenotype

Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Background: The aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder. Methods: Case-control study: 19 consecutive patients (17 female) with TTS compared to 76 controls without TTS, were randomly selected from the database of a Nationwide epidemiological study after matching (gender, age and residence) by controls. Psychiatric diagnoses were carried out according to the ICD-10 using semi-structured interview tools (ANTAS-SCID) administered by clinical staff. Quality of Life (Qol) was assessed by means of SF-12. Results: Only Major Depressive Disorders (MDD) showed higher frequencies in cases with statistical significance difference (p=0.014) as well as at least one Mood Disorder Diagnosis [MDD or BD] (p=0.002). The lifetime prevalence of at least one anxiety disorder with no comorbid mood disorder did not show a higher frequency in cases (p=0.57). The score at SF 12 in the TTS group was similar to those of controls (p=0.71)In the TTS group, the score at SF-12 in people with one mood or anxiety diagnosis (N=7) was similar to those without mood or anxiety diagnosis (p=0.75). The use of antidepressants was higher in TTS group (15.79% vs 1.31%; p=0.030). Conclusion: The study shows an association between TTS with depressive disorders and antidepressants use and does not confirm the association with anxiety syndromes. The study suggests the need to investigate the possible interactions between antidepressants use and mood disorders in studies with appropriate design and sample size

Efficacy of Intracolonic Administration of Low-Molecular-Weight Heparin CB-01-05, Compared to Other Low-Molecular-Weight Heparins and Unfractionated Heparin, in Experimentally Induced Colitis in Rat

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