relief revival reincarnation

there is a complex connectivity that we have with the built environment that goes beyond visual aesthetics and stimulates each of our senses. this connectivity is tied to our identity and the way we contextualize our experiences and our world. inspired by ethnographic observations, oscar newman’s seminal work, + the pruitt-igoe documentary, the project seeks to study the elements of this connectivity or in some cases the reduced connectivity within a public housing residential environment. what contributes to this reduced connectivity? newman examined it from an architectural perspective, exterior elements of building, space designation, corridors, skip|stop elevators, circulation patterns, natural surveillance opportunities. other researchers (domestic + international) emphasized the importance of interior elements that contribute to a sense of belonging and ownership that include personalization, spatial layout, light, relational qualities between rooms, occupancy standards, and the spaces that support socialization

A comparison of mental health service delivery programs in Arkansas public school systems

This primarily descriptive research study was designed to provide an initial review of the mental health services being offered in the Arkansas public school system by assessing the current delivery of these services and examining certain demographic correlates. The study utilized an established national survey instrument, developed by SAMHSA, which was administered as an email survey to 140 Arkansas schools. The respondents for this study were the Local Education Agencies/Special Education Supervisors in individual school districts. Seventy-eight schools (55%) completed the survey, including 26 elementary schools, 25 junior high schools and 27 high schools. Sixty-two schools (79.5%) identified themselves as rural school districts and 16 schools (20.5%) were identified as urban schools. Eighteen (23.0 %) schools reported operating a school-based mental health clinic, while 60 (77%) had mental health services provided by community providers, but were not identified as having a school-based clinic. Schools identified 12,061students (30.0%) as recipients of mental health services in the schools in the 2007-2008 school year. Several objectives reviewed in this study were: the way mental health services are organized administratively (under the special education department or in a separate department), how staff is organized (hired by district or via contract with the district), where authority rests for various administrative tasks (hiring and supervision of staff), what type of mental health services are being provided, what primary mental health problems are exhibited by children receiving these services, what data the schools are currently collecting, and the mechanisms used by the school to coordinate mental health and educational services between the school and the community. The study found significant results by identifying the following specific needs: services barriers among rural children, specific mental health-related problems reported for boys and girls, unmet service provision for Hispanic children, methodological strategies with respect to specific informants used for data collection, deficiencies in data collection among some schools, and lack of coordination of strategic planning across school districts

Health Data Sharing Preferences of Consumers: Public Policy and Legal Implications of Consumer-Mediated Data Management

University of Minnesota Ph.D. dissertation. May 2017. Major: Nursing. Advisors: Connie White Delaney, Daniel Pesut. 1 computer file (PDF); vi, 136 pages.An individual’s choice to share or have control of the sharing or withholding of their personal health information is one of the most significant public policy challenges associated with electronic information exchange. There were four aims of this study. First, to describe predictors of health data sharing preferences of consumers. Second, to test a hypothesized path diagram to understand the strength, path, and direction of relationships between and among the constructs of information privacy, data security, data sharing preferences, and consumer-mediated exchange (C-ME). Third, to create a theoretical model. Fourth, to make recommendations describing data governance structures needed for personally identifiable information in consumer-mediated data management. Study findings indicate two levels of health data sharing preferences exist (a) sharing between providers and (b) personal access to health information. The theoretical model showed data security and information privacy have a positive, direct relationship on consumer health data sharing preferences with respect to the types of data and mechanisms used to share personally identifiable health information. Results of this study were used to propose an integrated system approach to design, management, and control of consumer-mediated data management

Clinical comanagement of Lasik post-operative complications

This guide provides the optometrist with a quick reference of LASIK post-operative complications currently reported in ophthalmology literature. Since LASIK is becoming a popular procedure, many more optometrists are comanaging post-operative LASIK patients. The complications of LASIK are unique and not found in primary care clinical guides. The description, prevalence, etiology, symptoms, signs, differential diagnosis, and management are presented for each complication. Additional sections aimed at preventing complications are LASIK contraindications, consultation criteria for screening LASIK candidates, a pre-operative examination, and a post-operative examination. Primary sources and review articles are provided for the optometrist to reference. This guide puts a clinically useful LASIK management guide at the fingertips of optometrists

Does therapeutic horseback riding decrease balance deficits in community-dwelling older adults?

Hippotherapy and therapeutic riding (TR) provide pleasurable activity and physical exercise to individuals and yet limited study is available on its therapeutic value to improve balance in older adults. In this study, the researchers measured the benefit of TR on balance and quality of life in communitydwelling older adults. A convenience sample of individuals 65 years and older was recruited from a local community. The study is a single-blind, pretest-posttest, controlled study of a 10-session TR program with a Professional Association of Therapeutic Horsemanship (PATH) trained and certified TR instructor. Each TR session included grooming and tacking, mounting, a warm-up exercise on the horse, riding, and dismounting. The results of this study showed a significant improvement in balance scores as well as participant perception of overall health after the intervention period. Therefore, this study illustrated the practicality, safety, and benefit on improvement of balance in community-dwelling older adults from a short-term TR program. However, the small sample size prevented the data from being conclusive. Larger scale studies should be conducted to clinically prove the benefit of therapeutic riding for older adults. Therapeutic riding has the potential to improve balance and increase quality of life in older adults. Connecting the results from this study to the larger issue of fall prevention may provide evidence to include hippotherapy or TR in occupational therapy for older adults with balance deficits

Exploring the Relationship Between Fidelity of Implementation and Academic Achievement in a Third-Grade Gifted Curriculum: A Mixed-Methods Study

This study used sequential mixed-methods analyses to investigate the effectiveness of a research-based language arts curriculum for gifted third graders. Using analytic induction, researchers found that teachers’ beliefs and expectations (time, sense of autonomy, expectations for students, professional expertise) influenced the degree to which they implemented the research intervention with fidelity to its design. Next, maximum variation sampling and quantitative analysis of student outcomes determined that postassessment achievement test scores are higher for students in classrooms with teachers who show high fidelity or adherence to the intervention

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

The use of IL-2/JES6-1 Ab complex (IL-2 Ab Cx) has been considered as a potential therapeutic for inflammatory diseases due to its selective expansion of regulatory T cells (Tregs) in mice. Here, IL-2 Ab Cx was explored as a therapeutic agent to reduce joint inflammation induced by chikungunya virus, an alphavirus causing debilitating joint disease globally. Virus-infected mice treated with IL-2 Ab Cx exhibited exacerbated joint inflammation due to infiltration of highly activated CD4(+) effector T cells (Teffs). Virus infection led to upregulation of CD25 on the Teffs, rendering them sensitive towards IL2 Ab Cx. Ready responsiveness of Teffs to IL-2 was further demonstrated in healthy human donors, suggesting that the use of IL-2 Ab Cx in humans is not suitable. Changes in IL-2 sensitivity during active virus infection could change the responsive pattern towards the IL-2 Ab Cx, resulting in the expansion of pro-inflammatory rather than anti-inflammatory responses

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8(+) T cells into the brain and prevents Plasmodium-induced neuropathology

Arboviral diseases have risen significantly over the last 40 years, increasing the risk of co‐infection with other endemic disease such as malaria. However, nothing is known about the impact arboviruses have on the host response toward heterologous pathogens during co‐infection. Here, we investigate the effects of Chikungunya virus (CHIKV ) co‐infection on the susceptibility and severity of malaria infection. Using the Plasmodium berghei ANKA (PbA) experimental cerebral malaria (ECM ) model, we show that concurrent co‐infection induced the most prominent changes in ECM manifestation. Concurrent co‐infection protected mice from ECM mortality without affecting parasite development in the blood. This protection was mediated by the alteration of parasite‐specific CD8+ T‐cell trafficking through an IFN γ‐mediated mechanism. Co‐infection with CHIKV induced higher splenic IFN γ levels that lead to high local levels of CXCL 9 and CXCL 10. This induced retention of CXCR 3‐expressing pathogenic CD8+ T cells in the spleen and prevented their migration to the brain. This then averts all downstream pathogenic events such as parasite sequestration in the brain and disruption of blood–brain barrier that prevents ECM ‐induced mortality in co‐infected mice

Ca-Stimulated Type 8 Adenylyl Cyclase Is Required for Rapid Acquisition of Novel Spatial Information and for Working/Episodic-Like Memory

Ca-stimulated adenylyl cyclases (ACs) transduce neuronal stimulation-evoked increase in calcium to the production of cAMP, which impinges on the regulation of many aspects of neuronal function. Type 1 and type 8 AC (AC1 and AC8) are the only ACs that are directly stimulated by Ca. Although AC1 function was implicated in regulating reference spatial memory, the function of AC8 in memory formation is not known. Because of the different biochemical properties of AC1 and AC8, these two enzymes may have distinct functions. For example, AC1 activity is regulated by both Ca and G-proteins. In contrast, AC8 is a pure Ca sensor. It is neither stimulated by Gs nor inhibited by Gi. Recent studies also suggested that AC1 and AC8 were differentially concentrated at different subcellular domains, implicating that Ca-stimulated signaling might be compartmentalized. In this study, we used AC8 knock-out (KO) mice and found behavioral deficits in memory retention for temporal dissociative passive avoidance and object recognition memory. When examined by Morris water maze, AC8KOmice showed normal reference memory. However, the acquisition of newer spatial information was defective in AC8 KO mice. Furthermore, AC8 KO mice were severely impaired in hippocampus-dependent episodic-like memory when examined by the delayed matching-to-place task. Because AC8 is preferentially localized at the presynaptic active zone, our results suggest a novel role of presynaptic cAMP signaling in memory acquisition and retention, as well as distinct mechanisms underlying reference and working/episodic-like memory