The association between fever and pyuria in children older than one month

Introduction: Some assumptions have been made on the probable association between fever and pyuria. Objectives: The present study aimed to investigate the association between fever and pyuria. Patients and Methods: In this case-control study, 90 febrile and 90 non-febrile children aged more than one month who were admitted to the pediatric ward were included. Urine specimens of children less than 2 years of age were collected by urine bag. Midstream urine samples were collected and immediately sent to the laboratory for complete urinalysis and urine culture. Results: Overall, 6.7% in febrile children and 2.2% in control group had pyuria however there was no significant association between fever and pyuria (P>0.05). Additionally, no association between the presence of pyuria and type of disease was detected (P>0.40). Conclusion: The present study could not reveal any association between fever and pyuria in children older than one month. Keywords: Pyuria, Interstitial nephritis, Feve

Anuria in solitary kidney patient with gastroenteritis: A case report study

For better management of acute kidney injury (AKI) and prevention of progressive renal injury, it is extremely important to manage infections such as gastroenteritis. In addition, anuria is considered a risk factor for AKI and even causes death in patients. An 18-month-old boy with vomiting and diarrhea for three days and anuria for 24 hours was referred to Farsan hospital. The patient had bulky and watery diarrhea about 7-8 times a day and vomited 3-4 times a day which was containing food particles. He had a fever on the first and second days. Ultrasound findings revealed that the right kidney did not exist, and the left kidney was affected by compensatory hypertrophy. Disorders in the patient’s blood biochemical factors were also observed. Acidosis and other biochemical disorders were treated with bicarbonate drip, allopurinol, Lasix drip, and dopamine drip. After about 18 hours, anuria was treated

Osseous reaction to implantation of two endodontic cements : mineral trioxide aggregate (MTA) and calcium enriched mixture (CEM)

Aim: The aim of the present in vivo study was to determine bone tissue reaction to calcium enriched mixture (CEM) and mineral trioxide aggregate (MTA) using a rat femur model. Study Design: Sixty-three rats were selected and randomly divided into three groups of 21 each [experimental groups (n=15), control (n=6)]. Implantation cavities were prepared in each femoral bone and randomly filled with the biomaterials only in the experimental groups. The animals in three groups were sacrificed 1, 4, and 8 weeks postoperatively. Histologic evaluations comprising inflammation severity and new bone formation were blindly made on HE-stained decalcified 6-?m sections. Results: At 1, 4, and 8 weeks after implantation number of inflammatory cells had decreased in the CEM, MTA and control groups, respectively, with no statistically significant differences. Conversely, new bone formation had increased in all the experimental and control groups, without statistically significant differences. Conclusion: The results suggest that biocompatibility of MTA, as gold standard, and CEM cement as a new endodontic biomaterial are comparabl

Nutrients as novel therapeutic approaches for metabolic disturbances in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women. This disease is characterized by infertility, menstrual dysfunction, and hyperandrogenism. Also, PCOS is often associated with hyperlipidemia and impaired glucose tolerance, conditions that are associated with cardiovascular disorder, type 2 diabetes, cancer and hypertension. Evidence supports that some nutrients may affect the hormonal and metabolic disturbances of PCOS. Here in this study, we aimed to review the available literature that assessed the nutrients such as inostol, isoflavonids, resveratrol, vitamin D, and PUFA (polyunsaturated fatty acids), known to influence the hormonal and metabolic disturbances of PCOS, along with the strategies and future directions of nutrient supplementations in such patients

Comparison of Canal Preparation Pattern of K3 and ProTaper Rotary Files in Curved Resin Blocks

INTRODUCTION: The purpose of this study was to evaluate and compare canal preparation pattern of K3 and ProTaper rotary files in curved resin blocks. MATERIALS AND METHODS: Twenty-four resin blocks were used in this experimental study and randomly divided into two groups. Their initial images were scanned. After preparation, their images were scanned again in the same position. Pre and post preparation images were superimposed by Photoshop software and the removed resin was measured in 5 different points, and then analyzed statistically by ANOVA and T-test. RESULTS: At O point (orifice), significantly (P<0.05) more outer canal wall was removed in the ProTaper group than in the K3 group. There was no significant difference at any other points of outer wall. Removed material of inner canal wall was not significantly different between the two groups. CONCLUSION: Under the condition of this study, both systems performed acceptable preparation pattern except at the beginning of the curve

Effect of Long-time Mild Heat Stress on Proliferative, Differentiation and Bone Regeneration Capabilities of Dental Pulp Stem Cells

Introduction: The application of various strategies, including heat stress, has been attempted to maintain and improve mesenchymal stem cells (MSCs) plasticity and efficiency for bone regeneration. Although cell responses to heat stress are one of the most examined cellular stress responses, most studies, in this context, investigated the effect of that for a short period. Hence, the current study aimed to investigate the properties of MSCs, derived from dental pulp stem cells (DPSCs) following long-term heat stress. Materials and Methods: DPSCs was loaded on β-tricalcium phosphate scaffold blocks and cultivated at elevated temperature up to 39 ° C. In vitro, DPSC properties, including proliferation, osteogenic differentiation, and bone regeneration in vivo, have been evaluated. Results: The results of in vitro study showed that mild heat stress for a lengthy period could maintain and improve both the proliferative and differentiation potential of DPSCs during in vitro expansion and differentiation. Also, bone regeneration in vivo showed increased bone regeneration in the cells cultivated at a higher temperature. Conclusion: This study provided evidence for the beneficial effects of the administration of mild heat stress for an extended period to maintain and improve DPSC properties, which may serve as a starting point for developing clinically compliant procedures for MSC treatment before transplantation

Surgical stabilization of a distal tibial fracture in a jungle cat (Felis chaus) using orthogonal double plating

Abstract The jungle cat (Felis chaus) is a member of the genus Felis within the family Felidae, native to south‐east Asia, west Asia and north Africa. A 2‐year‐old male jungle cat was referred with a history of lameness of 3 days duration. At the time of presentation, the animal had non‐weight‐bearing lameness of the right hindlimb. Examination identified crepitation and instability in the distal diaphyseal region of the right tibial bone. Radiographs confirmed the presence of fractures in the distal diaphyseal region of the right tibia and fibula. Double plating of the tibia was employed for used fixation. The animal was evaluated 2, 4 and 8 weeks post‐operatively, and the procedure was considered to have been successful with no observed surgical complications

Efficacy of Potassium Citrate Solution in the Treatment of Renal Microlithiasis in Children 1 Month to 15 Years-old

Abstract Background and objective: The present research aims to determine efficacy of potassium citrate solution in the treatment of renal microlithiasis in children one month to 15 years old in   Shahrekord Pediatric Nephrology Clinic. Methodology: In this clinical trial study, 60 children aged 1 month to 15 years referred to Shahrekord Pediatric Nephrology Clinic who had one or two (microlithiasis) less than 3 mm in ultrasound; They were included in the study by available sampling. Children were randomly divided into 2 groups receiving placebo (water) and receiving potassium citrate solution. After 3 months, the number and size of stones and the consequences of stones were recorded in both groups and analyzed using SPSS software and relevant statistical tests. Results: Out of 60 children studied, 34 were male (56.7%) and 26 were females (43.3%) with a mean age of 61.62 47 47.54 months. After 3 months of intervention, the mean number and size of stones in each group had a significant decrease (P <0.001) and this amount was lower in the group receiving potassium citrate than the group receiving placebo, but this difference was not statistically significant (<0.05). P). Also, the consequences of kidney stones in both groups were similar and there was no significant difference (P <0.05). Conclusion: The results of this study showed that potassium citrate solution has no effect on the treatment of one or two microlithiasis in children and in these patients the use of supportive therapy is still sufficient. Keywords: Kidney stones, Microlithiasis, Children, Potassium citrat

Local and Systemic Administration of Mesenchymal Stem Cells in Regeneration of Mandibular Defects: An Experimental Study

Introduction: Mesenchymal stem cells (MSCs) have been utilized as an aid in regeneration of bone defects however due to the poor homing ability via systemic injection, local administration, genetic manipulation has been used more. The present study aimed to compare the local and systemic application of MSCs in regeneration of bone defects. Materials and Methods: Sixty Wistar male rats were used in this study. Circular 5×5 mm bone defects were created in the angle of the mandible. Autogenous bone marrow mesenchymal stem cells (BMMSCs) were obtained and culture expanded. Green fluorescent positive (GFP+) transfection has been performed for the possible detection of the cells in the healed bone. The rats were randomly treated in four groups; 1. Beta tricalcium phosphate (β-TCP) scaffold seeded with MSC (β-TCP+MSC), 2. Intravenous MSC injection with β-TCP scaffold in the defect (MSC), 3. β-TCP without cell therapy (β-TCP) and 4. Control defects that left empty. The rats were euthanized after 8 weeks. New bone formation (BF) were investigated by hematoxylin and eosin staining. Results: Localized cell therapy (β-TCP+MSC group) showed the highest healing rate (BF= 54.05±2.39%) followed by MSC systemic injection (BF= 22.69±3.87%) (P≤0.05). Inflammatory cells infiltration was evident dominantly in systemic injection cell group. Immunohistchemical analysis showed existence of the MSCs around the defects. GFP+ cells were mainly detected in the defect in β-TCP+MSC group while few GFP+ cells were detected in the MSC systemic group. Conclusion: local application of the MSCs with synthetic scaffold showed better results than intravenous administration of MSCs in treatment of rat mandible bone defects.&nbsp