Suicidal Ideation in Patients With Gender Identity Disorder in Western Iran From March 2019 to March 2020

Background: In recent years, the number of patients with gender identity disorder (GID) has rapidly increased. These people are at risk of adverse life events that influence their health and wellbeing. Research studies have also shown a significant rate of suicide in these individuals. This study aims to determine the prevalence of suicidal ideation in patients with GID referred to Legal Medicine Office in Ilam Province.Methods: In study sample comprised 21 patients without psychiatric comorbidity visited the Legal Medicine Office in Ilam Province for confirmation of transsexuals from March 2019 to March 2020. GID disorder was diagnosed through a GIDYQ (A-A) questionnaire and clinical interview. The Beck scale for suicide ideation was used to clarify and measure the intensity of attitudes, behaviors, and planning for a suicide attempt.Results: In 21 patients with GID, the average score for suicide ideation was 11.6. The average age of patients was 19 years, and all of them were single. In this sample, 19.1% had low risks, 71.5% high risks, 9.5% had very high-risk suicide ideation. Linear regression analysis showed that higher education and higher age were risk factors for suicide ideation in patients with GID.Conclusion: The high rate of suicidal ideation in patients with gender identity disorder makes it essential to pay attention to their mental health. It should be noted that suicidal thoughts can be a basis for suicide attempts

Design of a mechanically closed-loop test rig for testing aviation industry’s gearboxes

Due to the wide usage of rotary equipment and the necessity of their testing for maintenance and repair, test rigs have become necessary. The mechanical closed-loop test rig developed in Sharif University of Technology branch of ACECR (Academic Centre of Education, Culture and Research) is a test rig with low energy losses that is suitable for testing high power gearboxes such as aerospace or wind turbine gearboxes. It can be loaded up to 489Hp at a maximum speed of 3000 rpm, and the test components can be tested in different testing conditions including a variety of torques and speeds. This paper describes the preliminary, conceptual, and detailed design, steps including frame work design, control system design, hydraulic system and torque generator design asn well as a dynamic and static analysis of the whole system. Also a simplified model of the system is presented and qualified, and some data of test rig’s working conditions is presented. These data includes the temperature change of the gearboxes, their vibration in time, and also the variation of torque, hydraulic pressure, and motor speed. Furthermore, the relation between these parameters is investigated to determine the behaviour of the system. The validity of the system’s dynamic modelling is also investigated and verified

Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo

Introduction Vitiligo pathogenesis is complicated, and several possibilities were suggested. However, it is well-known that the metabolism of pigments plays a significant role in the pathogenicity of the disease. Objectives We explored the role of amino acids in vitiligo using targeted metabolomics. Methods The amino acid profile was studied in plasma using liquid chromatography. First, 22 amino acids were derivatized and precisely determined. Next, the concentrations of the amino acids and the molar ratios were calculated in 31 patients and 34 healthy individuals. Results The differential concentrations of amino acids were analyzed and eight amino acids, i.e., cysteine, arginine, lysine, ornithine, proline, glutamic acid, histidine, and glycine were observed differentially. The ratios of cysteine, glutamic acid, and proline increased significantly in Vitiligo patients, whereas arginine, lysine, ornithine, glycine, and histidine decreased significantly compared to healthy individuals. Considering the percentage of skin area, we also showed that glutamic acid significantly has a higher amount in patients with less than 25% involvement compared to others. Finally, cysteine and lysine are considered promising candidates for diagnosing and developing the disorder with high accuracy (0.96). Conclusion The findings are consistent with the previously illustrated mechanism of Vitiligo, such as production deficiency in melanin and an increase in immune activity and oxidative stress. Furthermore, new evidence was provided by using amino acids profile toward the pathogenicity of the disorder.Peer reviewe

Potential Molecular Mechanisms of Bisphenol A in Obesity Development

Bisphenol A (BPA), an endocrine disruptor, is associated with metabolic disorders. However, several studies have suggested that exposure to BPA can cause obesity. It has recently got more attention from scientists as a risk factor for obesity due to its ability to mimic natural estrogens and bind to their receptors. Nonetheless, the molecular mechanism underpinning the environmental etiology of metabolic disorders has not been not fully clarified. In this regard, BPA exposure directly disrupts endocrine regulation, neuroimmune and signaling pathways, and gut microbes, resulting in obesity. In addition, epidemiological studies have revealed a significant relationship between BPA exposure and the development of obesity, although conflicting results have been reported. Therefore, this review summarized the possible role and molecular mechanisms associated with BPA exposure that may lead to obesity based on in vivo and in vivo studies

Les nouvelles dimensions de la politique étrangère de l'Iran

L'Iran aujourd'hui entretient des relations aussi bien avec la Chine Populaire qu'avec les deux Super-Grands, et a établi des rapports basés sur l'entente et la coopération avec l'Europe et le monde arabe. Fort de ses richesses pétrolières et de sa nouvelle puissance financière, l'Iran semble avoir voulu donner de nouvelles dimensions à sa diplomatie. Sa position géographique, de même que sa force militaire, lui attribuent par ailleurs des chances de jouer un rôle plus réel dans la région du Moyen-Orient et du golfe Persique. Corrélativement, ce pays riche d'expériences historico-politiques a des possibilités non négligeables pour appliquer pleinement sa "politique d'indépendance nationale", syâsaté mostaghéllé melli.Mozafari Mehdi. Les nouvelles dimensions de la politique étrangère de l'Iran. In: Politique étrangère, n°2 - 1975 - 40ᵉannée. pp. 141-159

Transformations sociales et problèmes politiques en Iran

Mozafari Mehdi. Transformations sociales et problèmes politiques en Iran. In: Politique étrangère, n°5 - 1978 - 43ᵉannée. pp. 557-578

Identification and Prioritization of Effective Interventions in the Control of the COVID-19 Pandemic using DEMATEL Method

Introduction: COVID-19, which appeared in December 2019, has impressed the whole world. The corona virus had far-reaching effects on all health care systems and has had a direct impact on almost all areas of human life in all countries of the world, which has led countries to take various public and social health measures. Making decisions during the coronavirus pandemic has numerous challenges. In this study, a multi-criteria decision-making method called DEMATEL was used to identify and prioritize effective interventions in the control of the COVID-19 pandemic. Material & Methods:  Effective interventions to control COVID-19 were identified using literature review, and these factors were then ranked employing DEMATEL. Furthermore, three experts specialized in DEMATEL methodology were requested to rank 21 influential factors identified based on the relative importance. Findings: The results of this study showed that prompt and timely public health measures (20/238), home quarantine for patients and carriers (20/130), appropriate patient tracking with the implementation of Shahid Soleimani plan (19/383), the availability of health services and social services during the quarantine (19/239), and educational interventions regarding public acceptance of the vaccine (19/161) are the most important effective interventions in controlling the COVID-19 pandemic. Discussion & Conclusion: The results of the study showed that 21 interventions were effective in controlling the COVID-19 pandemic .According to the identification and prioritization of effective interventions obtained from this study, using DEMATEL method, it is possible to control coronavirus infection in the community with high accuracy

Turkey’s Foreign Policy in South Caucasus and Interests of Iran and Russia

With power succession of “ justice and development” party in Turkey in 2002 the foreign policy of this country in regional and far regional relations has seriously changed. Before 2000 Turkeys foreign policy was far westernized and the government policy-making was west, specially US, oriented. But with rise of justice and development government in Turkey, the country’s foreign policy changed to a multidimensional pragmatic interest-based policy .one aspect of this policy modified foreign policy toward collaboration with neighbors in order to enhance Turkey’s role in the region including south Caucasus. This study tries to evaluate Turkey foreign policy in Caucasus and its conflicting interests with the two powerful countries of area – Iran and Russia. The main question of this study is concentrated on the Turkey’s Caucasian Policy and its affects on interests of Iran and Russia. The hypothesis of the paper is that new Turkey’s foreign policy in the region brought contradiction between the country and two abovementioned powerful neighbors

Convergence Analysis of Quantum-inspired Genetic Algorithms with the Population of a Single Individual

ABSTRACT In this paper, the Quantum-inspired Genetic Algorithms with the population of a single individual are formalized by a Markov chain model using a single and the stored best individual. Here, we analyze the convergence property of the Quantum-inspired Genetic Algorithms based on our proposed mathematical model, and with assumption in which its special genetic operation in the generation changes is restricted to a quantum operator; and show by means of the Markov chain analysis that the algorithm with preservation of the best individual in the population and comparison of it with the existing individual, will converge on the global optimal solution