Second Harmonic Detection of Atmospheric Trace Gases with a Train-Pulse Driven Lead-Salt Tunable Diode Laser for an Operation at Peltier Cooling Temperature

SYNOPSIS Is proposed a tunable diode laser absorption spectrometer system which employs a pulsed current to drive the diode laser still implementing a second-harmonic detection methods enhancing a signal to noise up to 104 times that the case without it. This system affords the lead-salt diode laser a higher operating temperature which allows a more compact deep cooling system. A principle is based on employing a gated integrator between the preamplifier and the lock-in amplifier. Investigations are made on the optimum selection of the gating aperture time interval as determined by response time of the infrared detector and the pulse width of the laser driving current

Color prediction modeling for five-channel CMYLcLm printing

In printing, halftoning algorithms are applied in order to reproduce a continuous-tone image by a binary printing system. The image is transformed into a bitmap composed of dots varying in size and/or frequency. Nevertheless, this causes that the sparse dots found in light shades of cyan (C) and magenta (M) appear undesirably noticeable against white substrate. The solution is to apply light cyan (Lc) and light magenta (Lm) inks in those regions. In order to predict the color of CMYLcLm prints, we make use of the fact that Lc and Lm have similar spectral characteristics as C and M respectively. The goal of this paper is to present a model to characterize a five-channel CMYLcLm printing system using a three-channel color prediction model, where we treat the ink combinations Lc+C and Lm+M as new compound inks. This characterization is based on our previous three-channel CMY color prediction model that is capable of predicting both colorimetric tri-stimulus values and spectral reflectance. The drawback of the proposed model in this paper is the requirement of large number of training samples. Strategies are proposed to reduce this number, which resulted in expected larger but acceptable color differences

Food-borne trematodiases in East Asia: epidemiology and burden

Food-borne trematodiases are a cluster of parasitic helminth infections in humans and animals and belong to the cluster of neglected tropical diseases. The causative helminths dispose of a complex life cycle. As with many helminth infections, most infected people may only experience mild and non-specific clinical signs and symptoms. However, repeated, heavy and long-term infections may lead to severe clinical manifestations and also potentially fatal complications such as cholangiocarcinoma. Diagnosis remains a challenge as reliable, affordable, rapid, and simple-to-use diagnostic techniques are not available. If correctly and early diagnosed, safe, cheap, efficacious, orally administered drugs are available. Globally, the disease burden of food-borne trematodiases is estimated to be well within the range of other and better known neglected tropical diseases (e.g. dengue, leishmaniasis, lymphatic filariasis, onchocerciasis, and schistosomiasis) with a concentration in East and Southeast Asia. Food-borne trematodiases are zoonoses and may also have a negative impact on agri- and aquacultural production in affected regions. Mathematical modelling and analysis of food-borne trematodiases transmission dynamics to inform control and prevention is still in a very early stage, also due to the very limited availability of essential data. The current mainstay of human food-borne trematodiases control is drug-based morbidity control. For improved control, prevention or even elimination, more integrated efforts adopting also an ecosystem and “One Health” perspective are needed