On Government Investment and Production

This paper critically evaluates the argument that all government spending is, from the perspective of economic theory, simply consumption spending. The argument is questionable because it assumes that for investment to be meaningful, it must be directed toward consumer satisfaction, where “consumers” are a group mutually exclusive from government officials. Further, it assumes that government officials can be neither future- or consumeroriented in their behavior. Related to these points, the argument also contains terminology structured so as to rule out objections simply by definition. In addition, the consumptiontheory of government spending also potentially incorporates hidden value judgments. Finally, the argument actually overlooks important facts about government production which would otherwise go unnoticed

The Relationship Between Prior Experiences in Mathematics and Pharmacy School Success

Objective. To assess students’ pre-pharmacy math experiences, confidence in math ability, and relationship between experiences, confidence, and grades in math-based pharmacy courses. Methods. A cross-sectional survey of first year to third year pharmacy students was conducted. Students reported type of pre-pharmacy math courses taken, when they were taken [high school (HS) vs. college] and year of HS and college graduation. Students rated their confidence in math ability using the previously validated 11-item Fogerty Math Confidence Scale (Cronbach alpha=0.92). Math grade point average (GPA), Pharmacy College Admission Test quantitative (PCAT quant) scores, and grades (calculations and kinetics) were obtained from transcripts and school records. Spearman correlation and multivariate linear regression were used to compare math experiences, confidence, and grades. Results. There were 198 students who reported taking math courses 7.1 years since HS graduation and 2.9 years since their last schooling prior to pharmacy school. Students who took math courses with more time since HS/last schooling had lower calculations and kinetics grades. Students reporting having taken more HS math courses had better calculations grades. Students with higher math GPA, and PCAT quant scores also had higher calculations and kinetics grades. Greater confidence in math ability was associated with higher calculations grades. In multivariate regressions, PCAT quant scores and years since HS independently predicted calculations grades, and PCAT quant scores independently predicted kinetics grades. Conclusion. The number of pre-pharmacy math courses and time elapsed since they were taken are important factors to consider when predicting a pharmacy student’s success in math-based pharmacy school courses

The Efficacy of Microfracture in the treatment of Athletes with Full Thickness Chondral Injuries

INTRODUCTION: Sports injuries can often result in full thickness chondral lesions. If left untreated, these injuries can lead to localized pain, inflammation, effusion and further cartilage injury. Such injuries in an athlete can be career ending. The current recommendation for treatment is microfracture. Many studies have evaluated this technique in the general population, but only minimal attention has been given specifically to athletes. METHODS: The focus of this study was to review the current literature for the last ten years on all studies pertaining to treatment of athletes who suffered full thickness chondral injuries and were treated with microfracture. The majority of studies reviewed evaluated microfracture without comparison against other modalities. Only one study compared microfracture with autologous osteochondral transplantation (OAT). RESULTS: Of the five studies that were evaluated in this review, all showed improvement in functional ability and a decrease in pain post microfracture surgery. The ability of the athlete to return to their sport at a pre-injury level showed variability among the studies. CONCLUSION: Microfracture is an effective technique in the management of full thickness chondral injuries, however given the results of microfracture in comparison to OAT, it may not be the best option. Further studies, including more comparison trials will help to establish the best treatment modalities for both immediate and long term management

Analysis of rolling group therapy data using conditionally autoregressive priors

Group therapy is a central treatment modality for behavioral health disorders such as alcohol and other drug use (AOD) and depression. Group therapy is often delivered under a rolling (or open) admissions policy, where new clients are continuously enrolled into a group as space permits. Rolling admissions policies result in a complex correlation structure among client outcomes. Despite the ubiquity of rolling admissions in practice, little guidance on the analysis of such data is available. We discuss the limitations of previously proposed approaches in the context of a study that delivered group cognitive behavioral therapy for depression to clients in residential substance abuse treatment. We improve upon previous rolling group analytic approaches by fully modeling the interrelatedness of client depressive symptom scores using a hierarchical Bayesian model that assumes a conditionally autoregressive prior for session-level random effects. We demonstrate improved performance using our method for estimating the variance of model parameters and the enhanced ability to learn about the complex correlation structure among participants in rolling therapy groups. Our approach broadly applies to any group therapy setting where groups have changing client composition. It will lead to more efficient analyses of client-level data and improve the group therapy research community's ability to understand how the dynamics of rolling groups lead to client outcomes.Comment: Published in at http://dx.doi.org/10.1214/10-AOAS434 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

Polymer Translocation Dynamics in the Quasi-Static Limit

Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium. The system is modeled as a flexible hard-sphere chain that translocates through a cylindrical hole in a hard flat wall. In some calculations, the nanopore is connected at one end to a spherical cavity. Translocation times are measured directly using MC dynamics simulations. For sufficiently narrow pores, translocation is sufficiently slow that the mean translocation time scales with polymer length N according to \propto (N-N_p)^2, where N_p is the average number of monomers in the nanopore; this scaling is an indication of a quasi-static regime in which polymer-nanopore friction dominates. We use a multiple-histogram method to calculate the variation of the free energy with Q, a coordinate used to quantify the degree of translocation. The free energy functions are used with the Fokker-Planck formalism to calculate translocation time distributions in the quasi-static regime. These calculations also require a friction coefficient, characterized by a quantity N_{eff}, the effective number of monomers whose dynamics are affected by the confinement of the nanopore. This was determined by fixing the mean of the theoretical distribution to that of the distribution obtained from MC dynamics simulations. The theoretical distributions are in excellent quantitative agreement with the distributions obtained directly by the MC dynamics simulations for physically meaningful values of N_{eff}. The free energy functions for narrow-pore systems exhibit oscillations with an amplitude that is sensitive to the nanopore length. Generally, larger oscillation amplitudes correspond to longer translocation times.Comment: 13 pages, 13 figure

Flow behaviour of ponded turbidity currents

Sea floor topography can constrict, deflect or reflect turbidity currents resulting in a range of distinctive deposits. Where flows rebound off slopes and a suspension cloud collects in an enclosed basin, ponded or contained turbidites are deposited. Ponded turbidites have been widely recognised in slope mini-basins and on small, structurally-confined basin floors in strike-slip and foreland basin settings. They can have a variable internal structure the significance of which remains poorly understood in terms of flow behaviour. New experiments demonstrate that the ponding process can comprise up to four phases: 1) cloud establishment, 2) inflation, 3) steady-state maintenance, and 4) collapse. The experiments explored the behaviour of sustained turbidity currents draining into small basins and show that the ponded suspensions that form are characterised by an important internal interface; this divides a lower outbound-moving layer from an upper return layer. The basal layer evolves to constant concentration and grain size, whereas the upper layer is graded (concentration and grain size decrease upward). During the cloud inflation stage, the concentration and velocity profiles within the ponded suspension evolve and this phase can dominate the resulting deposit. Outbound internal waves can travel along the interface between the outbound and return layers and impinge against the confining slope and their amplitude is highest when the inter-layer density contrast is greatest, e.g., when the input flows are thin and dense. The experiments show that flow reversals can arise in several ways (initial rebound, episodic collapse of the wedge of fluid above the counter slope, ‘grounding’ of the internal velocity interface) and that despite steady input, velocities decay and the deposit grades upwards. Internal waves emanate from the input point, i.e., do not form as reflections off the counter slope. The internal grain size interface within the suspension may dictate textural trends in sands onlapping the confining slopes. Where flows are partially ponded, internal waves can generate pulsing overspill to basins down dip

Epitaxial Y1Ba2Cu3O7 thin films on CeO2 buffer layers on sapphire substrates

Pulsed laser deposition has been used to deposit Y1Ba2Cu3O7 layer on CeO2 buffer layers on (1102) sapphire. Both layers are epitaxial with the (110) direction of the CeO2 layer aligned with the direction of the sapphire substrate. The c-axis Y1Ba2Cu3O7 layer has its direction aligned with the direction of the CeO2. Cross-sectional transmission electron microscopy shows the epitaxy to be coherent and the interfaces to be abrupt at an atomic level. The best films have a critical current of 9 e6 A/cm2 at 4.2 K and lower microwave surface resistance than copper at 77 K and at a frequency of 31 GHz.Comment: 3 pages, 2 figures, journal articl

Hybrid Event Beds Generated By Local Substrate Delamination On A Confined-Basin Floor

The outer parts of deep-water fans, and the basin plains into which they pass, are often described as areas where erosion is negligible and turbidite systems have net aggradation. Nevertheless sedimentological and stratigraphic analysis of outer fan lobe and confined basin plain deposits in Cretaceous-Paleocene Gottero Sandstone (NW of Italy) has revealed extensive but cryptic bedding-parallel substrate-delamination features at the base of many sheet-like event beds. These comprise a variety of shallow but wide scour structures showing evidence of lateral expansion by sand-injection. The scours commonly occur at the base of beds made up of a basal clean sandstone overlain by argillaceous sandstone containing abundant mudstone clasts and locally large substrate rafts (up to 20 meters long). These strata are interpreted as a type of hybrid event bed. Field observations suggest that mud-clast entrainment occurred by delamination at the base of dense sandy flows. The large rafts, in some cases only partly detached, were incorporated in the flows locally and then carried for short distances (100s m to a few km) before partly disaggregating and undergoing deformation due to internal shearing. The development of such features may be common in flat and/or confined basin settings where high-volume flows interact with a cohesive and well layered substrate (e.g. muddy outer fans or confined or ponded basins with thick mudstone caps). Delamination is therefore suggested as an alternative mechanism leading to the formation of hybrid event beds following local substrate entrainment on the basin floor as opposed to on more remote slopes and at channel-lobe transition zones

Relationship between Exposureto Class Size Reductionand Student Achievementin California

The CSR Research Consortium has been evaluating the implementation of the Class Size Reduction initiative in California since 1998. Initial reports documented the implementation of the program and its impact on the teacher workforce, the teaching of mathematics and Language Arts, parental involvement and student achievement. This study examines the relationship between student achievement and the number of years students have been exposed to CSR in grades K-3. The analysis was conducted at the grade level within schools using student achievement data collected in 1998-2001. Archival data collected by the state were used to establish CSR participation by grade for each school in the state. Most students had one of two patterns of exposure to CSR, which differed by only one year during grade K-3. The analysis found no strong association between achievement and exposure to CSR for these groups, after controlling for pre-existing differences in the groups