Annotated bibliography of α-benzildioxime

The references are presented chronologically. The names and configurations used by each author are retained. In this regard it should be noted that the presently accepted configuration of α-benzildioxime (anti) was not proposed until 1921, and was not generally accepted until somewhat later. The syn-configuration was generally used before 1921

Integrated project management system of scientific and technical centre in oil company "Rosneft"

Concept and structure of three level integrated project management system of in project-oriented organization have been suggested and described. Synergetic effect at such system introduction is achieved due to systemic actions in such directions as: increasing organization controllability and transparence of decision making; flow of documentation regulation; formalization and optimization of project activity; development of irredundant and consistent system of normative documents in all directions of organization activit

THE PROBLEM OF ECOLOGICAL EDUCATION AND THE PROSPECTS OF ECOLOGIZATION

Environmental education and upbringing are the basis of the ecological well-being of society, and environmental competence is becoming an important factor in the formation of personality. Today, environmental education in the Republic of Belarus is based on the principle of continuity, it operates at all levels of education and implies continuous replenishment of the population’s knowledge in biology, ecology, environmental protection etcetera. Nevertheless, there are a number of problems that do not allow to fully reveal the potential of environmental education, for example, in higher education institutions. The analysis of syllabus and the rethinking of the educational process will lead to significant progress in the field of education ecologization.Экологическое образование и воспитание являются основой экологического благополучия общества, а экологическая компетентность становится важным фактором становления личности. На сегодняшний день экологическое образование в Республике Беларусь основывается на принципе непрерывности, то есть действует на всех ступенях образования и подразумевает постоянное пополнение знаний населения в областях биологии, экологии, охраны окружающей среды и прочих. Тем не менее, существует ряд проблем, которые не позволяют в полной мере раскрыть потенциал экологического образования, в частности, в высших учебных заведениях. Анализ учебных планов и переосмысление ведения учебного процесса смогут дать значительный прогресс в области экологизации образования

Family history and gastric cancer risk: A pooled investigation in the stomach cancer pooling (STOP) project consortium

Research is still required to establish the relationship between family history (FH) and gastric cancer (GC) in relation to different histological types and anatomical sites. The present work aimed to examine the influence of first-degree FH on the risk of GC, also according to the GC location and histological type, including 5946 cases and 12,776 controls from 17 studies of 11 countries in three continents participating in the Stomach Cancer Pooling (StoP) Project consortium. This analysis confirms the effect of FH on the risk of GC, reporting an approximately doubled risk, and provides further quantification of the risk of GC according to the subsite and histotype. Although there is a clear relationship between family history (FH) and the risk of gastric cancer (GC), quantification is still needed in relation to different histological types and anatomical sites, and in strata of covariates. The objective was to analyze the risk of GC according to first-degree FH in a uniquely large epidemiological consortium of GC. This investigation includes 5946 cases and 12,776 controls from 17 studies of the Stomach Cancer Pooling (StoP) Project consortium. Summary odds ratios (OR) and the corresponding 95% confidence intervals (CIs) were calculated by pooling study-specific ORs using fixed-effect model meta-analysis techniques. Stratified analyses were carried out by sex, age, tumor location and histological type, smoking habit, socioeconomic status, alcohol intake and fruit consumption. The pooled OR for GC was 1.84 (95% CI: 1.64-2.04; I2 = 6.1%, P heterogeneity = 0.383) in subjects with vs. those without first-degree relatives with GC. No significant differences were observed among subgroups of sex, age, geographic area or study period. Associations tended to be stronger for non-cardia (OR = 1.82; 95% CI: 1.59-2.05 for subjects with FH) than for cardia GC (OR = 1.38; 95% CI: 0.98-1.77), and for the intestinal (OR = 1.92; 95% CI: 1.62-2.23) than for the diffuse histotype (OR = 1.62; 95% CI: 1.28-1.96). This analysis confirms the effect of FH on the risk of GC, reporting an approximately doubled risk, and provides further quantification of the risk of GC according to the subsite and histotype. Considering these findings, accounting for the presence of FH to carry out correct prevention and diagnosis measures is of the utmost importance

Polyphenol intake and gastric cancer risk: Findings from the stomach cancer pooling project (stop)

Phenolic compounds may exert a favorable effect on the risk of several cancer types, including gastric cancer (GC). However, selected polyphenol classes have not been adequately investigated in relation to GC. The aim of this study is to evaluate the association between the intake of polyphenols in relation to GC risk. We used data from the Stomach cancer Pooling (StoP) Project, including 10 studies from six countries (3471 GC cases and 8344 controls). We carried out an individual participant data pooled analysis using a two-stage approach. The summary odds ratios (ORs) of GC for each compound, and the corresponding 95% confidence intervals (95% CI), were computed by pooling study specific ORs obtained through multivariate logistic regression, using random effect models. Inverse associations with GC emerged for total polyphenols (OR = 0.67, 95% CI = 0.54–0.81, for the highest versus lowest quartile of intake), total flavonoids (OR = 0.73, 95% CI = 0.55–0.90), anthocyanidins (OR = 0.74, 95% CI = 0.56–0.92), flavanols (OR = 0.77, 95% CI = 0.66–0.88), flavanones (OR = 0.57, 95%CI = 0.44–0.69), total phenolic acids (OR = 0.75, 95%CI = 0.55–0.94), and hydroxybenzoic acids (OR = 0.73, 95%CI = 0.57–0.89). Results were consistent across strata of age, sex, social class, and smoking habit. Suggestive inverse associations were also found for flavonols (OR = 0.76, 95%CI = 0.51–1.01) and hydroxycinnamic acids (OR = 0.82, 95%CI = 0.58–1.06). Further investigations from longitudinal data are needed to confirm this association