コウネンジ ガクセイ ガッシュク ケンシュウ セイカガイ ジュギョウ ニヨル キャリア ケイセイ シエン キョウイク ノ コウカ ト カノウセイ ニツイテ ノ ジッセンテキ ケンキュウ

平成18 年度と19 年度に、歯学部４年生に対して１泊２日の合宿研修を正課外授業として実施し た。本事業は、コミュニケーション能力の開発を通じてより良き医療人を育成することが目的である。 合宿研修場所は徳島県内の海洋センターであった。リラックスした雰囲気で海洋プログラムからスター トし、次いで、コミュニケーションに対する導入的なゲームや講演、そしてワークショップにより自分 たち自身で問題点を抽出し、さらに解決するための討論を行い、その結果をプレゼンテーションをする という内容であった。平成19 年度の２回目には、医学部と薬学部の協力を得て、実施テーマとして「コ ミュニケーション能力の育成」に「医療専門職としてのキャリア形成支援」という新たなテーマを加え、 チーム医療の定義や実践を学ぶ機会を設けて実施した。従来の正課授業と異なった教育方法の可能性に ついて成果を基に検証し、今後のキャリア形成支援教育への応用の可能性について考察した。Two days training camp for the fourth year students of dental school was executed in 2006 and 2007. The purpose of this program is to develop good practical dental doctors through the promotion of communication skills. The training camp was held at the YMCA oceanic center in Anan city of Tokushima Prefecture. It began with an oceanic program under relaxed atmosphere, and then, the programs containing games, lectures, and workshops related to communication skills were carried out. The theme " support for career formation as a medical profession" was added to "promotion of communication skills" in 2007, and then the skills to learn the definition and the practice of the medical team treatment were installed and executed. The usefulness of methodology different from the regular course class was verified based on the results, and the possibility of the application in the future curriculum for the career formation was discussed in the paper

Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate

Acquisition of cis-regulatory elements is a major driving force of evolution, and there are several examples of developmental enhancers derived from transposable elements (TEs). However, it remains unclear whether one enhancer element could have been produced via cooperation among multiple, yet distinct, TEs during evolution. Here we show that an evolutionarily conserved genomic region named AS3_9 comprises three TEs (AmnSINE1, X6b_DNA and MER117), inserted side-by-side, and functions as a distal enhancer for wnt5a expression during morphogenesis of the mammalian secondary palate. Functional analysis of each TE revealed step-by-step retroposition/transposition and co-option together with acquisition of a binding site for Msx1 for its full enhancer function during mammalian evolution. The present study provides a new perspective suggesting that a huge variety of TEs, in combination, could have accelerated the diversity of cis-regulatory elements involved in morphological evolution

Characterizing Interdisciplinarity of Researchers and Research Topics Using Web Search Engines

Researchers' networks have been subject to active modeling and analysis. Earlier literature mostly focused on citation or co-authorship networks reconstructed from annotated scientific publication databases, which have several limitations. Recently, general-purpose web search engines have also been utilized to collect information about social networks. Here we reconstructed, using web search engines, a network representing the relatedness of researchers to their peers as well as to various research topics. Relatedness between researchers and research topics was characterized by visibility boost-increase of a researcher's visibility by focusing on a particular topic. It was observed that researchers who had high visibility boosts by the same research topic tended to be close to each other in their network. We calculated correlations between visibility boosts by research topics and researchers' interdisciplinarity at individual level (diversity of topics related to the researcher) and at social level (his/her centrality in the researchers' network). We found that visibility boosts by certain research topics were positively correlated with researchers' individual-level interdisciplinarity despite their negative correlations with the general popularity of researchers. It was also found that visibility boosts by network-related topics had positive correlations with researchers' social-level interdisciplinarity. Research topics' correlations with researchers' individual- and social-level interdisciplinarities were found to be nearly independent from each other. These findings suggest that the notion of "interdisciplinarity" of a researcher should be understood as a multi-dimensional concept that should be evaluated using multiple assessment means.Comment: 20 pages, 7 figures. Accepted for publication in PLoS On

Successful laparoscopic resection of virilizing ovarian steroid cell tumor, not otherwise specified, in a 22-year-old woman: a case report and evaluation of the steroidogenic pathway

Objective: Ovarian steroid cell tumor (SCT) is a rare tumor with steroid-producing ability. We report a 22-year-old woman with secondary amenorrhea and hirsutism caused by an ovarian SCT-not otherwise specified (NOS), who underwent successfully laparoscopic resection of the tumor. Case report: A 22-year-old null gravida woman presented to a hospital, having amenorrhea for 18 months and increasing facial hair. Physical examination revealed obesity (body mass index, 37.3 kg/m2) with evident facial and trunk hair. Total and free serum testosterone, and dehydroepiandrosterone sulfate levels were found to be elevated. Levels of serum adrenocorticotropic hormone, gonadotropins, cortisol, aldosterone, and ovarian steroids were observed to be within reference intervals. Although polycystic ovaries were not found, a hyperechogenic solid tumor (3 cm) was detected on transvaginal ultrasonography. Laparoscopic resection of the tumor was performed. One month post-surgery, total and free testosterone levels were observed to have decreased, and menstruation resumed two months thereafter. The patient was histologically diagnosed with ovarian SCT-NOS. Expression of ovarian steroidogenic enzymes, which are related to hyperandrogenism, was observed. No disease recurrence has been reported for more than 5 years post-surgery