Emotional Phenomenology: Toward a Nonreductive Analysis

In this article I want to create a presumption in favor of a nonreductive analysis of emotional phenomenology. The presumption relies on the claim that none of the nonemotional elements which are usually regarded as constitutive of emotional phenomenology may reasonably be considered responsible for the evaluative character of the latter. In section 1 I suggest this is true of cognitive elements, arguing that so-called ‘evaluative’ judgments usually result from emotional, evaluative attitudes, and should not be conflated with them. In section 2 I argue the same holds true for conative attitudes (desires and acts of the will). And in section 3 I briefly mention some salient aspects of the version of nonreductive analysis I lean toward.Phenomenology of thinking past and present (Crédit classique, PhéCog)

Compte rendu de Nelly Wolf et Matthieu Rémy (dir.), Ce que Mai 68 a fait à la littérature

L’ouvrage coordonné et dirigé par Nelly Wolf et Matthieu Rémy entend principalement « faire un sort à l’idée reçue selon laquelle l’évènement lui-même [Mai 68] n’avait pas fait l’objet d’un roman digne de ce nom . » Plus largement, il s’agit de s’attaquer à la routine critique confinant au lieu commun et déplorant généralement la stérilité littéraire (voire le « grand trou » selon Pierre Michon) de Mai 68. Les arguments présentés par Wolf et Rémy sont de deux ordres : premièrement, Mai 68 au..

Développement d'un anticorps monoclonal anti-RANKL pour le traitement de la maladie de Paget

CHATENAY M.-PARIS 11-BU Pharma. (920192101) / SudocSudocFranceF

Performance measurement of professors at two European universities : A study at the IECS Ecole de Management de Strasbourg in France and the Europa-

Background: In a context of belt-tightening policy and of increasing competition between universities in France and in Germany, universities and therefore professors are required to increase their efficiency and to provide evidence of it. Performance measurement systems are assumed to increase transparency and incentives within the university sector. Purpose: The purpose of this thesis is to analyze to which extent performance measurement of professors at one French and one German university is relevant and how this performance can be measured. The study is conducted at the business school l’IECS Ecole de Management de Strasbourg (France) and within the Faculty of Business & Economics at the Europa-Universität Viadrina in Frankfurt an der Oder (Germany). Method: Performance measurement is considered through the study and the comparison of two universities. Based on a theoretical framework including theories from the private sector, the public sector and the university sector, several in-depth interviews are conducted to collect facts and opinions from both professors and administrators and from both the IECS and the Viadrina. Conclusion: This study assesses the relevance of the measurement performance of professors at the IECS and the Viadrina. It provides also the main areas where professors’ performance should be measured and the main methods to measure this performance. Lastly the thesis raises several issues linked to performance measurement such as the organizational culture of universities, the utilisation of performance measurement system information and the impacts of performance measurement

Biocompatible photoresistant far-red emitting, fluorescent polymer probes, with near-infrared two-photon absorption, for living cell and zebrafish embryo imaging.

International audienceExogenous probes with far-red or near-infrared (NIR) two-photon absorption and fluorescence emission are highly desirable for deep tissue imaging while limiting autofluorescence. However, molecular probes exhibiting such properties are often hydrophobic. As an attractive alternative, we synthesized water-soluble polymer probes carrying multiple far-red fluorophores and demonstrated here their potential for live cell and zebrafish embryo imaging. First, at concentrations up to 10 μm, these polymer probes were not cytotoxic. They could efficiently label living HeLa cells, T lymphocytes and neurons at an optimal concentration of 0.5 μm. Moreover, they exhibited a high resistance to photobleaching in usual microscopy conditions. In addition, these polymer probes could be successfully used for in toto labeling and in vivo two-photon microscopy imaging of developing zebrafish embryos, with remarkable properties in terms of biocompatibility, internalization, diffusion, stability and wavelength emission range. The near-infrared two-photon absorption peak at 910 nm is particularly interesting since it does not excite the zebrafish endogenous fluorescence and is likely to enable long-term time-lapse imaging with limited photodamage

Synthesis of multifunctional lipid-polymer conjugates: application to the elaboration of bright far-red fluorescent lipid probes

International audienceA new class of lipid-ended polymer conjugates presenting reactive sites regularly distributed along the polymer chain were synthesized using RAFT polymerization. The chosen modular approach enables preparation of different lipid families by tuning the nature of the phospholipid α-end, the molecular weight and the lateral functions of the polymer chain. The multiple activated ester functions of the conjugates can indeed be used for the efficient coupling of a great variety of amino-containing entities of interest. In this study, we elaborated original fluorescent lipid-polymer probes for optical microscopy by coupling along the chain a controlled number of chromophores emitting in the far-red where auto-fluorescence and light absorption by biological samples are limited. Water-soluble fluorescent lipid probes exhibiting an enhanced brightness were obtained. As a proof of concept, these probes were able to efficiently label the lipid bilayer of liposomes of various sizes. Such multifunctional lipid-ended polymers thus exhibit great potential to functionalize model and natural lipid assemblies

Vers une philosophie scientifique

Face à l'essor considérable des sciences cognitives, qu'est-on en droit d'attendre aujourd'hui de la philosophie ? Cette question est celle que se pose Brentano au XIXe siècle dans un contexte où l'explosion des sciences de la nature place la philosophie dans une crise sans précédent. Loin de se limiter à une simple épistémologie des sciences, Brentano saisit l'opportunité de cette crise pour non seulement asseoir de nouveau la philosophie sur le sol de l'expérience mais, également, définir la philosophie en tant que science. C'est cette dimension intégrée à la marche des sciences que nous avons perdue et qu'il s'agit de retrouver grâce à l'étude du programme de Brentano et de ses élèves : ses résultats appartiennent de plein droit, à l'histoire de la psychologie scientifique et permettent à la philosophie de gagner en positivité. Cet ouvrage, dirigé par Charles-Edouard Niveleau et à travers un très riche ensemble de contributions de spécialistes de premier plan, témoigne de l'ambition d'un tel programme philosophique, dont la reprise permettrait d'ouvrir la voie à une véritable interdisciplinarité avec les sciences de la cognition, pour le moment hors d'atteinte

(Bio)-conjugués polymères multifonctionnels pour l'imagerie de fluorescence

International audienc

(Bio)-conjugués polymères multifonctionnels pour l'imagerie de fluorescence

International audienc