12,902 research outputs found
Oscillatory Modes of a Prominence-PCTR-Corona Slab Model
Oscillations of magnetic structures in the solar corona have often been
interpreted in terms of magnetohydrodynamic waves. We study the adiabatic
magnetoacoustic modes of a prominence plasma slab with a uniform longitudinal
magnetic field, surrounded by a prominence-corona transition region (PCTR) and
a coronal medium. Considering linear small-amplitude oscillations, the
dispersion relation for the magnetoacoustic slow and fast modes is deduced
assuming evanescent-like perturbations in the coronal medium. In the system
without PCTR, a classification of the oscillatory modes according to the
polarisation of their eigenfunctions is made in order to distinguish modes with
fast-like or slow-like properties. Internal and external slow modes are
governed by the prominence and coronal properties respectively, and fast modes
are mostly dominated by prominence conditions for the observed wavelengths. In
addition, the inclusion of an isothermal PCTR does not substantially influence
the mode frequencies, but new solutions (PCTR slow modes) are present.Comment: Accepted for publication in Solar Physic
Second-order calculation of the local density of states above a nanostructured surface
We have numerically implemented a perturbation series for the scattered
electromagnetic fields above rough surfaces, due to Greffet, allowing us to
evaluate the local density of states to second order in the surface profile
function. We present typical results for thermal near fields of surfaces with
regular nanostructures, investigating the relative magnitude of the
contributions appearing in successive orders. The method is then employed for
estimating the resolution limit of an idealized Near-Field Scanning Thermal
Microscope (NSThM).Comment: 10 pages, 7 figure
Perturbation theory for plasmonic eigenvalues
We develop a perturbative approach for calculating, within the quasistatic
approximation, the shift of surface resonances in response to a deformation of
a dielectric volume. Our strategy is based on the conversion of the homogeneous
system for the potential which determines the plasmonic eigenvalues into an
inhomogeneous system for the potential's derivative with respect to the
deformation strength, and on the exploitation of the corresponding
compatibility condition. The resulting general expression for the first-order
shift is verified for two explicitly solvable cases, and for a realistic
example of a deformed nanosphere. It can be used for scanning the huge
parameter space of possible shape fluctuations with only quite small
computational effort
Cathodoluminescence hyperspectral imaging of trench-like defects in InGaN/GaN quantum well structures
Optoelectronic devices based on the III-nitride system exhibit remarkably good optical efficiencies despite suffering from a large density of defects. In this work we use cathodoluminescence (CL) hyperspectral imaging to study InGaN/GaN multiple quantum well (MQW) structures. Different types of trench defects with varying trench width, namely wide or narrow trenches forming closed loops and open loops, are investigated in the same hyperspectral CL measurement. A strong redshift (90Â meV) and intensity increase of the MQW emission is demonstrated for regions enclosed by wide trenches, whereas those within narrower trenches only exhibit a small redshift (10Â meV) and a slight reduction of intensity compared with the defect-free surrounding area. Transmission electron microscopy (TEM) showed that some trench defects consist of a raised central area, which is caused by an increase of about 40% in the thickness of the InGaN wells. The causes of the changes in luminescences are also discussed in relation to TEM results identifying the underlying structure of the defect. Understanding these defects and their emission characteristics is important for further enhancement and development of light-emitting diodes
Coincident electron channeling and cathodoluminescence studies of threading dislocations in GaN
We combine two scanning electron microscopy techniques to investigate the influence of dislocations on the light emission from nitride semiconductors. Combining electron channeling contrast imaging and cathodoluminescence imaging enables both the structural and luminescence properties of a sample to be investigated without structural damage to the sample. The electron channeling contrast image is very sensitive to distortions of the crystal lattice, resulting in individual threading dislocations appearing as spots with black–white contrast. Dislocations giving rise to nonradiative recombination are observed as black spots in the cathodoluminescence image. Comparison of the images from exactly the same micron-scale region of a sample demonstrates a one-to-one correlation between the presence of single threading dislocations and resolved dark spots in the cathodoluminescence image. In addition, we have also obtained an atomic force microscopy image from the same region of the sample, which confirms that both pure edge dislocations and those with a screw component (i.e., screw and mixed dislocations) act as nonradiative recombination centers for the Si-doped c-plane GaN thin film investigated
Dose de-escalation of intrapleural tissue plasminogen activator therapy for pleural infection. The alteplase dose assessment for Pleural infection Therapy project
Rationale: Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10 mg and DNase 5 mg administered twice daily has been shown in randomized and open-label studies to successfully manage over 90% of patients with pleural infection without surgery. Potential bleeding risks associated with intrapleural tPA and its costs remain important concerns. The aim of the ongoing Alteplase Dose Assessment for Pleural infection Therapy (ADAPT) project is to investigate the efficacy and safety of dose de-escalation for intrapleural tPA. The first of several planned studies is presented here.
Objectives: To evaluate the efficacy and safety of a reduced starting dose regimen of 5 mg of tPA with 5 mg of DNase administered intrapleurally for pleural infection.
Methods: Consecutive patients with pleural infection at four participating centers in Australia, the United Kingdom, and New Zealand were included in this observational, open-label study. Treatment was initiated with tPA 5 mg and DNase 5 mg twice daily. Subsequent dose escalation was permitted at the discretion of the attending physician. Data relating to treatment success, radiological and systemic inflammatory changes (blood C-reactive protein), volume of fluid drained, length of hospital stay, and treatment complications were extracted retrospectively from the medical records.
Results: We evaluated 61 patients (41 males; age, 57 ± 16 yr). Most patients (n = 58 [93.4%]) were successfully treated without requiring surgery for pleural infection. Treatment success was corroborated by clearance of pleural opacities visualized by chest radiography (from 42% [interquartile range, 22–58] to 16% [8–31] of hemithorax; P < 0.001), increase in pleural fluid drainage (from 175 ml in the 24 h preceding treatment to 2,025 ml [interquartile range, 1,247–2,984] over 72 h of therapy; P <  0.05) and a reduction in blood C-reactive protein (P < 0.05). Seven patients (11.5%) had dose escalation of tPA to 10 mg. Three patients underwent surgery. Three patients (4.9%) received blood transfusions for gradual pleural blood loss; none were hemodynamically compromised. Pain requiring escalation of analgesia affected 36% of patients; none required cessation of therapy.
Conclusions: These pilot data suggest that a starting dose of 5 mg of tPA administered intrapleurally twice daily in combination with 5 mg of DNase for the treatment of pl
Embedding Theory into Learning Technology Practice with Toolkits
Abstract: Expert and theoretical knowledge about the use of learning technology is not always available to practitioners. This paper illustrates one way in which practitioners can be supported in the process of engaging with theory in order to underpin practical applications in the use of learning technologies. This approach involves the design of decision-making resources, defined here as 'toolkits'. This concept is then illustrated with three practical examples. The ways in which this approach embeds specific theoretical assumptions is discussed, and a model for toolkit specification, design and evaluation is described.Editors: Simon Buckingham Shum (Open U.)
Reviewers: Martyn Cooper (Open U.), Simon Buckingham Shum (Open U.) Interactive demonstrations: This article includes links to the Media Adviser Toolkit and the Evaluation Toolkit.
Interactive demonstrations: This article describes the Media Adviser toolkit, which is available to download from http://www.unl.ac.uk/ltri/demos/demos.htm, and the Evaluation Toolkit [www.ltss.bris.ac.uk/jcalt/
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