Reflexiones críticas sobre la historia del pensamiento económico a propósito de un libro

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Proyecto de investigación sobre "El socorro a los pobres". Los opúsculos de Vives, Soto y Medina

Historia del Pensamiento Económico en España. Actas de las III Jornadas de Historia del Pensamiento Económico en España. Ernest Lluch I Martín, Pedro Schwartz Girón, Luis Perdices Blas (Eds.): Facultad de Ciencias Económicas de la Universidad de Barcelona. (11-12 de diciembre de 1987)Publicad

Juan Trías Vejarano, Del antiguo régimen a la sociedad burguesa

Este artículo reseña: Juan Trías Vejarano, Del antiguo régimen a la sociedad burguesa. Madrid. Tecnos, 2019, 272 pp.

Los Rothschild y las minas de Almadén : el servicio de la deuda pública española y la comercialización del mercurio de Almadén

Tesis Universidad Complutense de MadridDirector Pedro Schwartz Girón.Fac. de Ciencias Económicas y EmpresarialesTRUEProQuestpu

Estructura de incentivos e instituciones en el pensamiento económico español del siglo XVII

Este papel recoge algunas de las consideraciones del pensamiento arbitrista sobre la estructura institucional de España en el siglo XVII. En concreto repasamos su reflexión respecto a los mayorazgos, vínculos, censos y juros. También revisamos sus críticas a la administración de justicia. Consideramos que sus argumentos, de corte absolutamente económicos, son muy similares a los utilizados por la Nueva Economía Institucional y el Análisis Económico del Derecho de la actualidad

Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality

Ponencia invitadaRipening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ananassa), where current cultivars are derived from a narrow germplasm collection. Improving fruit quality requires two important breakthroughs: 1) a precise understanding of the fruit ripening process that will allow the targeting of relevant genes, and 2) the identification of novel alleles responsible for fruit quality traits. In our project, we aim at the identification and characterization of key transcription factors involved in fruit ripening regulation and their target genes, in order to infer the Gene Regulatory Network controlling this process. Also, we are using a collection of around two hundred wild strawberry (Fragaria vesca) accessions to identify loci involved in important traits such as aroma, size or resistance to pathogens. Finally, we are implementing the use of the genome-editing tool CRISPR/Cas9 in the cultivated strawberry, which we expect it might open opportunities for engineering this species to improve traits of economic importance.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Identification and characterization of RIPENINGLESS, a key transcription factor in the regulation of fruit development and ripening in the cultivated strawberry Fragaria × ananassa

Despite the advances that have allowed to elucidate transcription factors (TFs) involved in the development and ripening of non-climacteric strawberry fruits, key regulators of these processes remain to be identified. Among the plant TFs, the BEL class of Homeobox genes has been shown to control meristem formation and/or maintenance, organ morphogenesis, organ position, and several aspects of the reproductive phase in Arabidopsis thaliana (Bhatt et al., 2004; Byrne et al., 2003; Roeder et al., 2003; Smith and Hake, 2003). In this work, we have identified RIPENINGLESS (FaRPL), a BEL-like Homeodomain TF of the cultivated strawberry (Fragaria × ananassa), that shows an increase in its expression during ripening, peaking at the turning stage. To functionally characterize the role of FaRPL, we have established stable silencing (RNAi) and over-expression lines under the 35S promoter. FaRPL-RNAi lines showed a high rate of abortions. However, some lines achieved to develop full fruits, being firmer and with a lower water content than those of the control. Furthermore, the ripening progress was significantly delayed in these RNAi lines, in which a high percentage of fruits displayed a complete blockage at a stage similar to the turning stage in wt. Interestingly, fruits overexpressing FaRPL showed aberrant shapes, being enlarged in the base of the receptacles. All these results support an important role of this TF in fruit development and ripening. Finally, gene expression and hormone analyses point to an essential role of FaRPL in the regulation of ABA biosynthesis, being this phytohormone the main promoter of strawberry fruit ripening.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Role of wild rabbits as reservoirs of leishmaniasis in a non-epidemic Mediterranean hot spot in Spain

We would like to thank the hunters of the municipality of Montefrio for their support in the study. This study was funded by the Project, Ministry of Economy and Competitiveness, Instituto de Salud Carlos III, Madrid and Feder Funds for Regional Development from the European Union, "One way to make Europe". Funding for open access charge: Universidad de Granada/CBVA.There is limited information regarding the role of wild mammals in the transmission dynamics of Leishmania infantum. A potential human leishmaniasis hot spot was detected in southern Spain that could not be explained solely by canine leishmaniasis prevalence. The aim of this work was to analyse the involvement of wild rabbits as the main factor affecting this Mediterranean hot spot. A survey of wild rabbits, dogs and sand flies was conducted in the human cases environment. A nearby region without clinical leishmaniasis cases was used as reference control. 51 wild rabbits shot by hunters were analysed by molecular techniques. 1100 sand flies were captured and morphologically identified. Blood collected from patients’ relatives/ neighbours (n = 9) and dogs (n = 66) was used for molecular analysis and serology. In Mediterranean leishmaniasis hot spots such as Montefrío municipality (average incidence of 16.8 human cases per 100,000 inhabitants/year), wild rabbits (n = 40) support high L. infantum infection rates (100%) and heavy parasite burdens (average value: 503 parasites/mg) in apparently normal ear skin directly accessible to sand flies, enabling the existence of heavily parasitized Phlebotomus perniciosus females (12.5% prevalence). The prevalence of infection and median parasite load were very low among rabbits captured in Hu´escar (n = 11), a human clinical leishmaniasis-free area for the last 18 years. P. perniciosus was the most abundant Phlebotomus species in all the domestic/peridomestic microhabitats sampled, both indoors and outdoors. Accordingly, leishmaniasis is clustering in space and time at this local scale represented by Montefrío due to the proximity of two competent host reservoirs (dogs and heavily parasitized wild rabbits) associated with overlapping sylvatic and domestic transmission cycles through the main vector, P. perniciosus. We highlight the usefulness of determining the prevalence of infection and parasite burden in wild rabbits as a control leishmaniasis measure with the advantage that the use of the ear offers.Ministry of Economy and Competitiveness, Instituto de Salud Carlos III, MadridFeder Funds for Regional Development from the European Union, "One way to make Europe"Universidad de Granada/CBV