67 research outputs found
STUDY ON ANTIOXIDANT ACTIVITIES OF THE AERIAL PARTS AND SOME COMPOUNDS ISOLATED FROM Archidendron clypearia ((Jack) I. Niels Part 2. ISOLATING, DETERMINING STRUCTURE AND ANTIOXIDANT CAPABILITY OF SOME COMPOUNDS FROM ETHYL ACETATE EXTRACT
The antioxidant activity in vitro of methanol extract of Archidendron clypearia was evaluated by in vitro tests on isolated liver cells of mouses with ED50 value of 2.18 μg/mL compared to that of curcumin of 1.87 µg/mL. Using combined chromatographic methods, four compounds were isolated from chloroform extract of the Archidendron clypearia. Their structures were elucidated to be daucosterol, 1-octacosanol, docosenoic acid, and methyl gallate by 1D- and 2D-NMR spectroscopic methods and in comparison with those reported in the literature. This is the first report of these compounds from the plant. All four compounds showed quite high antioxidant activity, for which methyl gallate was the highest one
Comparison of Decontamination Standards
The quality of materials used in nuclear-related facilities is critical, especially the ease of decontamination of different paints and coatings. Standards describe different testing methods for classification. Nevertheless, compliance with these standards cannot be carried out negligibly from a safety point of view. In this study, a withdrawn Hungarian (MSZ-05 22.7662-83), an international ISO (ISO 8690:1988), and Russian (GOST 25146- 82) decontamination standard were compared. Four different paints were tested as part of this survey. The ease of decontamination varied mainly from poor to fair levels in the case of the Hungarian standard, while the ISO standard exhibited very good level. In the case of the Russian standard, only a theoretical comparison was carried out. Based on the results, it was found that a special epoxy-based coating can be recommended for isotope laboratories due to being the best material from an ease of decontamination point of view. From comparison of the standards considered here, it was found that the application of ISO standard is significantly faster and simpler than the withdrawn Hungarian standard. However, in the case of the Hungarian standard the data described the ease of decontamination in more details. The use of water or some other cleaning agents can be effective to remove 137 Cs and 60 Co contamination right after early identification. Isotope 137 Cs and 60 Co contamination of a surface can be cleaned quickly and effectively using distilled water for the 137 Cs isotope removal from the surfaces being several times easier than that of 60 Co
Limited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam: an epidemiological and genomic analysis.
OBJECTIVES: To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming. METHODS: Faecal samples from 204 randomly selected farmers and their chickens, and from 306 age- and sex-matched community-based individuals who did not raise poultry were collected. Antimicrobial usage in chickens and humans was assessed by medicine cabinet surveys. WGS was employed to obtain a high-resolution genomic comparison between ESBL-Ec isolated from humans and chickens. RESULTS: The adjusted prevalence of ESBL-Ec colonization was 20.0% (95% CI 10.8%-29.1%) and 35.2% (95% CI 30.4%-40.1%) in chicken farms and humans in Vietnam, respectively. Colonization with ESBL-Ec in humans was associated with antimicrobial usage (OR = 2.52, 95% CI = 1.08-5.87) but not with involvement in chicken farming. blaCTX-M-55 was the most common ESBL-encoding gene in strains isolated from chickens (74.4%) compared with blaCTX-M-27 in human strains (47.0%). In 3 of 204 (1.5%) of the farms, identical ESBL genes were detected in ESBL-Ec isolated from farmers and their chickens. Genomic similarity indicating recent sharing of ESBL-Ec between chickens and farmers was found in only one of these farms. CONCLUSIONS: The integration of epidemiological and genomic data in this study has demonstrated a limited contribution of non-intensive chicken farming to ESBL-Ec colonization in humans in Vietnam and further emphasizes the importance of reducing antimicrobial usage in both human and animal host reservoirs
Evaluating the initial result of transanal and transvaginal NOTES for colorectal cancer
Objective: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is an important evolution in minimally invasive surgery (MIS) nowaday. This paper presents the techniques and early results of the pure transanal and transvaginal laparoscopies (NOTES) used for the treatment of colorectal cancer. Material and method: Prospective studies were conducted at Hue Central Hospital, Vietnam. Patients: From December 2013 to September 2015, 22 cololorectal cancer patients (18 rectum, 3 sigmoid tumors and 1 descending colon), adenocarcinoma, T≤ T3N1M0. Methods: The patients were placed in lithotomy and Trendelenburg positions, and the lone-star retractor was placed in the anus (rectum cancer) or vagina (sigmoid cancer). The surgical cavity was then inflated with CO 2 and set at 12 mm/Hg. Dissection was continued until inside of the abdominal cavity (transanal technique). After that, the rectum was pushed into the abdominal cavity. The IMA and IMV were divided (TME included) in both techniques. After finishing dissection, the specimens were pulled out through the anus or vagina to prepare anastomosis. Coloanal and colorectal anastomosis were either hand-sewn (6 cases) or sealed with EEA staplers (16 cases). Results: 2 patients needed one more 5 mm umbilical port in RLQ, 2 patients needed two 5 mm trocars (post radiation hemorrhage, and urethral perforation). One patient converted to open and 1 patient converted to the HYBRID-NOTES procedure. The operation time was 258±40 (190-300) minutes. All patients required minimal analgesia. Bowel movement returned on the first day to 16 patients (average: two days, maximum: three days). The hospital stay was 7±2.8 (4-14) days. Kirwan classification (sphincter function) was very good (stage I: 18). Conclusions: Pure transanal and transvaginal laparoscopies for the treatment of colorectal cancer are feasible and safe. We believe that this is the first pure transvaginal laparoscopy (NOTES) for human in the world. A multicentric study in a large numbers of patients and a long follow-up is necessary
Состояние провоспалительного цитокинового звена у больных с нестабильной стенокарадией и сахарным диабетом 2-го типа в зависимости от функционального класса хронической сердечной недостаточности
Проанализировано состояние провоспалительного звена цитокинов у больных с нестабильной стенокардией (НС) и сопутствующим сахарным диабетом (СД) 2−го типа в зависимости от функционального класса хронической сердечной недостаточности (ХСН). Нарастание проявлений сердечной декомпенсации у больных с НС и СД 2−го типа ассоциируется с высокой активностью провоспалительного цитокинового звена, представленного фактором некроза опухолей−α и интерлейкином−6. Повышение функционального класса ХСН характеризуется увеличением инсулинорезистентности у больных с НС и СД 2−го типа.Проаналізовано стан прозапальної ланки цитокінів у хворих із нестабільною стенокардією (НС) та супутнім цукровим діабетом (ЦД) 2−го типу залежно від функціонального класу хронічної серцевої недостатності (ХСН). Наростання проявів серцевої декомпенсації у хворих із НС та СД 2−го типу асоціюється з високою активністю прозапальної цитокінової ланки, представленої фактором некрозу пухлин−α та інтерлейкіном−6. Підвищення функціонального класу ХСН характеризується зростанням інсулінорезистентності у хворих із НС та ЦД 2−го типу.The state of pro−inflammatory cytokines in patients with unstable angina (UA) and associated type 2 diabetes mellitus (DM) was analyzed depending on the functional class of chronic heart failure (CHF). The increase in manifestations of cardiac decompensation in patients with UA and type 2 DM is associated with high activity of pro−inflammatory cytokine level represented by tumor necrosis factor−β and interleukin−6. Increase of functional class of CHF is characterized by increased insulin resistance in patients with UA and type 2 DM
A taxonomy of information-centric networking architectures based on data routing and name resolution approaches
This study presents a vast coverage of current Information-Centric Network (ICN) submission by evaluating eight distinct and popular routing and name resolution approaches.Internet build-up and initial deposition were based on a host-driven approach.With the increasing demands for mediadriven data flooding the cost of the Internet, a new semantic and paradigm shift was envisioned known as ICN.Information Centrism is an approach that partly dissociates the host dependencies by referring to contents by unique identifiers called name.However, to benefit from the content network, forwarding, naming and routing, among other issues are still in its developmental stages.The taxonomy serves as a basis for research directions, challenges, implementation and future studies for standardizing the ICN routing and naming. Routing and Name Resolution were themed in categories of strategies, contributions, issues and drawbacks. The major findings of this paper are providing a classification and review of the data routing and name resolutions approaches that are proposed on eight ICN architectures; presenting drawback areas in the selected architectures; and finally highlighting some challenges of ICN routing for the ICN research community vending
TextANIMAR: Text-based 3D Animal Fine-Grained Retrieval
3D object retrieval is an important yet challenging task, which has drawn
more and more attention in recent years. While existing approaches have made
strides in addressing this issue, they are often limited to restricted settings
such as image and sketch queries, which are often unfriendly interactions for
common users. In order to overcome these limitations, this paper presents a
novel SHREC challenge track focusing on text-based fine-grained retrieval of 3D
animal models. Unlike previous SHREC challenge tracks, the proposed task is
considerably more challenging, requiring participants to develop innovative
approaches to tackle the problem of text-based retrieval. Despite the increased
difficulty, we believe that this task has the potential to drive useful
applications in practice and facilitate more intuitive interactions with 3D
objects. Five groups participated in our competition, submitting a total of 114
runs. While the results obtained in our competition are satisfactory, we note
that the challenges presented by this task are far from being fully solved. As
such, we provide insights into potential areas for future research and
improvements. We believe that we can help push the boundaries of 3D object
retrieval and facilitate more user-friendly interactions via vision-language
technologies.Comment: arXiv admin note: text overlap with arXiv:2304.0573
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