The effect of luteal phase gonadotropin-releasing hormone antagonist administration on IVF outcomes in women at risk of OHSS

Gonadotropin-releasing hormone (GnRH) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta. Objective: The aim of this study was to evaluate the effect of GnRH antagonist administration on pregnancy outcomes in early implantation period. Materials and Methods: In this retrospective study, 94 infertile women undergoing GnRH antagonist protocol who were at risk of ovarian hyperstimulation syndrome (OHSS) were included. Sixty-seven patients (group I) received Cetrorelix 0.25 mg/daily in the luteal phase for 3 days while in 27 participants (group II), it was not administered. Pregnancy outcomes were assessed based on chemical and clinical pregnancy rates. Results: The pregnancy outcomes were not significantly different between two groups (p=0.224). Conclusion: The present study proposed that luteal phase GnRH antagonist administration does not influence the chance of successful pregnancy outcomes

Comparison of the effects of vaginal royal jelly and vaginal estrogen on quality of life, sexual and urinary function in postmenopausal women

Introduction: Several causes can disturb the quality of life in postmenopausal women. Stress, urinary incontinence is one of the factors that can influence the quality of life of women, since they evade social activities and limit their behavior. Vulvovaginal disorders adversely impacts sexual action, psychosocial health, and partner relationships. Aim: The aim of this study was to examine the therapeutic properties of vaginal cream of royal jelly and estrogen on quality of life, sexual and urinary problems in postmenopausal women. Materials and Methods: This study was a randomized controlled clinical trial that was done on 90 married postmenopausal women 50 to 65-year-old. A total of 90 women were randomly distributed to three groups and were treated with vaginal cream of royal jelly 15%, lubricant, and conjugated estrogens for three months. Before and after intervention, quality of life and vaginal cytology were evaluated. Data was analysed by SPSS 16 using ANOVA and Tukey tests. Results: The results expressed that vaginal royal jelly is considerably more effective than conjugated estrogens and lubricant in improvement of quality of life and sexual and urinary function in postmenopausal women (p<0.05). Results of Pap smear showed that improvement of vaginal atrophy in conjugated estrogens group was better than other groups (p<0.001), and there was no significant difference between lubricant and royal jelly groups (p=0.89). Conclusion: The effectiveness of vaginal royal jelly in treatment of sexual and urinary problems of postmenopausal women is related to its estrogenic properties and could be suitable in promotion of life quality in postmenopausal women. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved

Melissa officinalis L: A Review Study With an Antioxidant Prospective.

Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail. This review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases up to 2016. The search terms used were "Melissa officinalis L," "antioxidant properties," oxidative stress," "oxidative damage", "ROS." Articles whose full texts were not available were excluded from the study. In this study, firstly, traditional usage of this herb was reviewed, including antimicrobial activity (antiparasitic, antibacterial, antiviral, etc), antispasmodic, and insomnia properties. Then, its antioxidant properties were overviewed. Various studies have shown that Melissa officinalis L possesses high amount of antioxidant activity through its chemical compounds including high amount of flavonoids, rosmaric acid, gallic acid, phenolic contents. Many studies confirmed the antioxidative effects of Melissa officinalis; thus, its effect in preventing and treating oxidative stress-related diseases might be reliable

Space Harpoon Projectile Analysis for Space Debris Capture

Space debris will become a more prevalent issue in this decade as technological advancements and greater dependencies on communications require more satellites in orbit, with some companies already hosting mega-constellations. Mitigating the debris using a space-tether is the most viable method to construct a space debris capture regime with current technology levels. Harpoon heads for the tethers are key design interests as these will penetrate through the satellites and/or debris. The focus of this paper is the analysis of an aluminium 6082, flat and conical head design, used to perforate aluminium 1050A plates using a gas gun laboratory. The aim is to conduct experiments to achieve a low Minimum Ballistic Velocity (MBV) where this velocity is the minimum velocity needed to perforate a material. Maximum perforation intertwined with minimal fragmentation is the desired balance sought from the designs. A high-speed camera records times taken for the events before and after perforation which deduces the MBV. 10 bar, 12.5 bar, and 15 bar of pressure were used, as well as 3mm, 1.5mm and 1mm Aluminium plate thickness, to provide diverse results for analysis. The MBV was calculated at 49.54m/s for 3mm thickness, with the conical head. The plates were cooled using dry ice to mimic space-like environments where tensile and yield strength increased with the cooler climates, resulting in higher MBVs. After impact, perforation profiles are analysed using a DSLR camera, resulting in ‘punches’ of material with the flat head and ‘petaling’ for the conical head. Conical perforation allows for material to be retained within the plate whilst flat head designs possess the potential for further space debris creation. The results retain reliability through validation checks with an oscilloscope and taking tolerances throughout the experiment. The results feed as a foundation to venture into future work with further ergonomic and bespoke designs

Efficacy of intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial

Background: Although pregnancy rate in in vitro fertilization-embryo transfer (IVF-ET) cycles has been increased over the preceding years, but the majority of IVF-ET cycles still fail. Granulocyte colony stimulating factor (GCSF) is a glycoprotein that stimulates cytokine growth factor and induces immune system which may improve pregnancy rate in women with history of implantation failure. Objective: The aim of this study was to evaluate GCSF ability to improve pregnancy rate in women with history of implantation failure Materials and Methods: 0.5 ml (300 μg/ml) GCSF was infused intrauterine in intervention group. Pregnancy outcomes were assessed based on clinical pregnancy. Results: The mean age of participants was 31.95±4.71 years old. There were no significant differences between demographic characteristics in two groups (p>0.05). The pregnancy outcome in GCSF group was improved significantly (p=0.043). Conclusion: GCSF can improve pregnancy outcome in patients with history of implantation failur

Analisis putusan pengadilan nomor 14/PID.SUS-ANAK/2018/PN.JKT.UTR tentang pencurian dengan pemberatan dihubungkan dengan pasal 85 undang-undang RI nomor 11 tahun 2012 tentang sistem peradilan anak

Fenomena kejahatan yang dilakukan oleh anak-anak akhir-akhir ini menunjukan gejala yang sangat mengkhawatirkan. Pada penelitian ini menganalisis hukuman yang ditetapkan kepada Alif Akbar Alwafi bin Kardiyono yang melakukan pencurian dengan pemberatan, sebagaimana telah diatur dalam pasal 363 ayat (1) ke-4 KUH Pidana jo Undang-Undang RI No 11 Tahun 2012 “tentang Sistem Peradilan Pidana Anak”. Namun pada kenyataannya dalam Putusan Pengadilan No 14/Pid.Sus-Anak/2018/PN.JKT.UTR tentang Pencurian dengan Pemberatan pelaku dijatuhi hukuman berdasarkan pasal 363 ayat (1) KUH Pidana, Undang-Undang Nomor 3 Tahun 1997 Tentang Pengadilan Anak, yang mana pada pasal 106 Undang-Undang RI Nomor 11 Tahun 2012 disebutkan bahwa Undang-Undang Nomor 3 Tahun 1997 tentang Peradilan Anak sudah dicabut dan dinyatakan tidak berlaku. Tujuan penelitian ini untuk mengetahui isi putusan hakim dalam kasus pencurian dengan pemberatan yang dilakukan oleh anak. Kemudian untuk mengetahui pertimbangan hukum hakim dan menganalisis Putusan Pengadilan Nomor 14/Pid.Sus-Anak/2018/PN.JKT.UTR, tentang “Pencurian dengan Pemberatan, serta mengetahui akibat hukum dari Putusan Pengadilan Nomor 14/Pid.Sus-Anak/2018/PN.JKT.UTR dihubungkan dengan Pasal 85 Undang-Undang RI Nomor 11 Tahun 2012 Tentang Sistem Peradilan Pidana Anak. Konsep berpikir penelitian ini berdasarkan pada Undang-Undang Dasar Tahun 1945 Pasal 28D Ayat (1), Teori “Perlindungan Masyarakat”, Peraturan Undang-Undang Nomor 3 Tahun 1997 Tentang Peradilan Anak, Undang-Undang RI Nomor 11 Tahun 2012 Tentang Sistem Peradilan Pidana Anak, dan KUH Pidana Pasal 363 Ayat (1) ke 4. Penelitian ini dilakukan dengan metode deskriptif-analisis, yaitu metode yang digunakan untuk menggambarkan atau menganalisis suatu hasil penelitian, serta analis data Putusan Pengadilan Nomor 14/Pid.Sus-Anak/2018/PN.JKT.UTR, tentang Pencurian dengan Pemberatan yang dihubungkan dengan Pasal 85 Undang-Undang RI Nomor 11 Tahun 2012 Tentang Sistem Peradilan Pidana Anak. Berdasarkan hasil analisis terhadap Putusan Pengadilan Nomor 14/Pid.Sus-Anak/2018/PN.JKT.UTR, tentang Pencurian dengan Pemberatan dapat disimpulkan bahwa Hakim menjatuhkan hukuman pidana penjara terhadap terdakwa berdasarkan Pasal 363 ayat (1) KUH Pidana, Undang-Undang Nomor 3 tahun 1997 tentang pengadilan anak. Dalam analisis, penulis lebih melihat pada tuntutan yang diberikan Jaksa Penuntut Umum sebagaimana diatur dalam Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak, Akibat hukumnya anak yang dijatuhi pidana penjara seharusnya ditempatkan di LPKA (Lembaga Pembinaan Khusus Anak)

Conjugate Effects of Radiation and Viscous Dissipation on Natural Convection flow over a Sphere with Pressure Work

ABSTRACT The effects of viscous dissipation and radiation on natural convection flow along a sphere with pressure work have been investigated. The governing equations are transformed into dimensionless non-similar equations by using set of suitable transformations and solved numerically by the finite difference method along with Newton&apos;s linearization approximation. We have focused our attention on the evaluation of velocity profiles, temperature profiles, shear stress in terms of local skin friction and the rate of heat transfer in terms of local Nusselt number for different values of radiation parameter, Prandlt number, heat generation parameter, magnetic parameter, joule heating parameter and viscous dissipation parameter and the numerical results have been shown graphically

Micronutrients and Anaemia

Micronutrient deficiencies and anaemia remain as major health concerns for children in Bangladesh. Among the micronutrient interventions, supplementation with vitamin A to children aged less than five years has been the most successful, especially after distribution of vitamin A was combined with National Immunization Days. Although salt sold in Bangladesh is intended to contain iodine, much of the salt does not contain iodine, and iodine deficiency continues to be common. Anaemia similarly is common among all population groups and has shown no sign of improvement even when iron-supplementation programmes have been attempted. It appears that many other causes contribute to anaemia in addition to iron deficiency. Zinc deficiency is a key micronutrient deficiency and is covered in a separate paper because of its importance among new child-health interventions