2,254 research outputs found

    The Absolution of Reynolds: The Constitutionality of Religious Polygamy

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    The ancient practice of polygamy became prevalent in parts of the United States in the mid-nineteenth century, when the Mormon Church canonized the doctrine of polygamy and encouraged its practice among its members. Today, there are nearly 40, 000 polygamists in the United States, mostly living in Utah. The Supreme Court has ruled on polygamy several times in decisions and dicta, each time finding it to be unconstitutional within the United States. In Reynolds v. United States, a 1878 decision upholding a statute that criminalized polygamy, the Court introduced the belief/action distinction that controls religious First Amendment doctrine today. This Note discusses the history of religious polygamy and argues that the Court should reexamine its previous rulings and should declare the practice of religious polygamy constitutional under the Free Exercise Clause of the First Amendment and the right to privacy within a marriage

    The 8-13 micron observations of Titan

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    Narrow band observations of Titan at selected wavelengths in the 8-13 micron range show evidence for a strong temperature inversion and the existence of at least one more spectroscopically active component in the atmosphere in addition to H2 and CH4

    PDB26 MODELLING COST EFFECTIVENESS OF BEHAVIOUR MODIFICATION PROGRAMMES AND EFFECTS ON MEDICATION: CASE STUDY OF EDUCATION PROGRAMMES IN DIABETES

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    PDB19 ESTIMATING THE COST EFFECTIVENESS IN THE UK OF VILDAGLIPTIN COMPARED TO PIOGLITAZONE AS ADD-ON THERAPY TO METFORMIN USING THE SHEFFIELD TYPE 2 DIABETES MODEL

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    Hemostasis biomarkers and incident cognitive impairment: the REGARDS study

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    Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related to incident CI over 3.5 years. Adjusted for other risk factors, 2+ abnormal markers (but not single ones) led to higher risk. SUMMARY: Background Vascular risk factors are associated with cognitive impairment, a condition that imposes a substantial public health burden. We hypothesized that hemostasis biomarkers related to vascular disease would be associated with the risk of incident cognitive impairment. Methods We performed a nested case-control study including 1082 participants with 3.5 years of follow-up in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a longitudinal cohort study of 30 239 black and white Americans aged ≥ 45 years. Participants were free of stroke or cognitive impairment at baseline. Baseline D-dimer, fibrinogen, factor VIII and protein C levels were measured in 495 cases who developed cognitive impairment during follow-up (based on abnormal scores on two or more of three cognitive tests) and 587 controls. Results Unadjusted odds ratios (ORs) for incident cognitive impairment were 1.32 (95% confidence interval [CI] 1.02-1.70) for D-dimer > 0.50 μg mL-1 , 1.83 (95% CI 1.24-2.71) for fibrinogen > 90th percentile, 1.63 (95% CI 1.11-2.38) for FVIII > 90th percentile, and 1.10 (95% CI 0.73-1.65) for protein C < 10th percentile. There were no differences in associations by race or region. Adjustment for demographic, vascular and health behavior risk factors attenuated these associations. However, having at least two elevated biomarkers was associated with incident cognitive impairment, with an adjusted OR of 1.73 (95% CI 1.10-2.69). Conclusion Elevated D-dimer, fibrinogen and FVIII levels were not associated with the occurrence of cognitive impairment after multivariable adjustment; however, having at least two abnormal biomarkers was associated with the occurrence of cognitive impairment, suggesting that the burden of these biomarkers is relevant

    Study of state-of-the-art static inverter design Final report, 6 Jan. - 6 Jun. 1966

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    Multiple purpose inverter design based on phase demodulated inverter circuit selected from state-of-the-art assessment of ten inverter circuit

    The Sensitivity of the Proportionality between Temperature Change and Cumulative CO2 Emissions to Ocean Mixing

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    The ratio of global mean surface air temperature change to cumulative CO2 emissions, referred to as transient climate response to cumulative CO2 emissions (TCRE), has been shown to be approximately constant on centennial time scales. The mechanisms behind this constancy are not well understood, but previous studies suggest that compensating effects of ocean heat and carbon fluxes, which are governed by the same ocean mixing processes, could be one cause for this approximate constancy. This hypothesis is investigated by forcing different versions of the University of Victoria Earth System Climate Model, which differ in the ocean mixing parameterization, with an idealized scenario of 1% annually increasing atmospheric CO2 until quadrupling of the preindustrial CO2 concentration and constant concentration thereafter. The relationship between surface air warming and cumulative emissions remains close to linear, but the TCRE varies between model versions, spanning the range of 1.2°–2.1°C EgC−1 at the time of CO2 doubling. For all model versions, the TCRE is not constant over time while atmospheric CO2 concentrations increase. It is constant after atmospheric CO2 stabilizes at 1120 ppm, because of compensating changes in temperature sensitivity (temperature change per unit radiative forcing) and cumulative airborne fraction. The TCRE remains approximately constant over time even if temperature sensitivity, determined by ocean heat flux, and cumulative airborne fraction, determined by ocean carbon flux, are taken from different model versions with different ocean mixing settings. This can partially be explained with temperature sensitivity and cumulative airborne fraction following similar trajectories, which suggests ocean heat and carbon fluxes scale approximately linearly with changes in vertical mixing
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