877 research outputs found
Taxation of the Internet Economy: An Analysis of the Recent Changes to Taxation of Airbnb and Short-Term Rentals in New Jersey
A Participational Managerial Method to Implement and Evaluate Information Security within a Healthcare Organizaton
The use of participational approaches to system design has been debated for a number of years. In some situations it seems that participational approaches are not a suitable or practical method by which to design an Information System or to analyse a problem. Within this paper we describe a framework in which participation plays an active and effective role and describe a method that was used to effectively design information systems and implement computer security countermeasures
The effectiveness of faecal removal methods of pasture management to control the cyathostomin burden of donkeys
Background:
The level of anthelmintic resistance within some cyathostomin parasite populations has increased to the level where sole reliance on anthelmintic-based control protocols is not possible. Management-based nematode control methods, including removal of faeces from pasture, are widely recommended for use in association with a reduction in anthelmintic use to reduce selection pressure for drug resistance; however, very little work has been performed to quantitatively assess the effectiveness of such methods.<p></p>
Methods:
We analysed data obtained from 345 donkeys at The Donkey Sanctuary (Devon, UK), managed under three different pasture management techniques, to investigate the effectiveness of faeces removal in strongyle control in equids. The management groups were as follows: no removal of faeces from pasture, manual, twice-weekly removal of faeces from pasture and automatic, twice-weekly removal of faeces from pasture (using a mechanical pasture sweeper). From turn-out onto pasture in May, monthly faecal egg counts were obtained for each donkey and the dataset subjected to an auto regressive moving average model.<p></p>
Results:
There was little to no difference in faecal egg counts between the two methods of faecal removal; both resulted in significantly improved cyathostomin control compared to the results obtained from the donkeys that grazed pasture from which there was no faecal removal.<p></p>
Conclusions:
This study represents a valuable and unique assessment of the effectiveness of the removal of equine faeces from pasture, and provides an evidence base from which to advocate twice-weekly removal of faeces from pasture as an adjunct for equid nematode control. Widespread adoption of this practice could substantially reduce anthelmintic usage, and hence reduce selection pressure for nematode resistance to the currently effective anthelmintic products.<p></p>
An Open Workflow Environment to Support Learning Data Science
The vast majority of visual tools to learn computing focus on imperative and object-oriented programming. This paper outlines a graphical tool and language which is makes functional programming accessible to inexperienced learners, while also supporting open access to the data and executable results for study and deployment. We believe that both the broadening of the range of programming paradigms and the open approach embedded in the tools make the materials valuable for learning
Nifty with data: can a business intelligence analysis sourced from open data form a nifty assignment?
This paper proposes a *nifty assignment* in data mining and discusses how quality in database assignments differs from other domains in computer science, particularly programming. It then considers the sources of data used, to study whether Open Data can form the basis of more such assignments, and if so how.
In the next sections, we describe the nifty assessment criteria and explain why use them as a standard for quality of assessment. We then propose an assignment which outlines a number of topics related to finding and accessing Open Data, merging sources, and analysing the data using self-service and data mining tools.
Once the assignment is clear, we will reconsider it against the nifty criteria, but also consider how the criteria themselves apply to the area of data mining which has few assignments proposed. Finally, we will consider whether the basis of this assignment, the use of Open Data as a source of data to analyse, can be extended to different cases and examples, and if so how.
Keyword : Nifty assignments; Open Data; Business Intelligence; Computer Science Educatio
Automated CNC Micromachining for Integrated THz Waveguide Circuits
Computer Numerically Controlled (CNC) machining
of splitblock waveguide circuits has become the primary method
of constructing terahertz waveguide circuits. The majority of
these circuits have been made on traditional CNC machining
centers or on custom-made laboratory machining systems. At
both the University of Arizona and Arizona State University, we
have developed techniques for machining splitblock waveguide
circuits using purpose-built ultra high precision CNC
machining centers designed for micromachining. These systems
combine the automation of a traditional CNC machining center,
including a high capacity toolchanger, workpiece and tool
metrology systems and a large work volume, with the precision
of custom laboratory systems. The systems at UofA and ASU
are built by Kern Micro and deliver typical measured
dimensional accuracies of 2-3 microns. Waveguide surface
finish has been measured with a Veeco white light
interferometric microscope to be Ra~75 nm. Tools of sizes
between 25 microns and 10mm are available, with toolchanger
capacities of 24-32 tools
Schwann cell-neuron interactions and axonal strain application in peripheral nervous system regeneration
Peripheral nervous system (PNS) injuries affect many people worldwide and if not repaired can leave individuals with the burden of living with chronic pain or motor dysfunction. My thesis focused on understanding the relationship nerves and neurons have with their environment during development and normal function in order to identify means by which the regenerative process might be manipulated and enhanced. The implementation of a two-armed study allowed me to investigate the interactions between Schwann cells (SCs), a vital neuronal support cell, and neurons, as well as, the role strain has in local protein synthesis. First, I detailed the changes in membrane stability within the two cell types. I was able to identify decreased velocity and correlative movement of neuronal membranes compared to SCs suggestive of a higher level of membrane stability. Both cell types saw a decreased trend in both velocity and correlative movement following development of contact with the other pointing to increased cellular membrane stability upon establishment of cellular contact. The next study looked into the development of ribosomal clusters within SC processes, which have been suggested to be a ribosomal source for axons following injury. I found that SCs develop ribosomal distributions early and use anterograde transport to maintain these populations. Upon the initiation of myelination, transport is depressed suggestive of a reduce role of ribosomes within the myelin fraction. The final portion of my work focused on neuronal adaptation to strain. I initially found that nerves are able to accommodate strains by straightening axons in a linear fashion. I further found moderate strain application to nerves upregulates the activation of both mTOR and S6, two molecules integral in enhancing protein synthesis. Additionally, increases in the cytoskeletal proteins β-actin and SMI31 were observed in response to strain. Suppression of the mTOR pathway with rapamycin led to an elimination of the effect on SMI31 but not β-actin. Rapamycin also enabled a strain-dependent reduction in tubulin levels. The results of my thesis contextualize the results of a number of studies that have observed advantageous regenerative outcomes from the use of SCs and strain for PNS recovery
Roundtable: Does All Human-Rights Funding Use a Human Rights-based Approach?
In this session, presenters and attendees will discuss different dimensions of the question, Does All Human-Rights Funding Use a Human Rights-based Approach?
In the U.S., grant strategies and decisions have historically been made by individuals and funders behind closed doors, with little transparency and accountability. Grant seekers, not to mention the public at large, have rarely had insight into how those decisions are made or any influence on the process. What criteria are they using? To whom are they accountable? And how do they make their decisions about what and who they are going to fund?
Replacing traditional hierarchical models of funding, participatory grantmaking applies a human rights-based approach to how funding is determined and who makes the funding decisions. The emphasis is on the practice as well as on the impact of the funds. In this participatory panel presentation, moderated by a staff person from the International Human Rights Funders Group (IHRFG), panelists and audience will explore a range of models for transforming the relationship of social justice actors with funders
The Auditory Comprehension of Unaccusative Verbs in Aphasia
Some persons with aphasia, particularly those diagnosed with a Broca’s aphasia, exhibit a delayed time course of lexical activation in canonically ordered S-V-O sentences (Ferrill et al., 2012) and delayed re-activation of displaced arguments in sentences that contain syntactic dependencies (Love et al., 2008). These patterns support the Delayed Lexical Activation (DLA) hypothesis: Lexical activation is delayed relative to the normal case, and thus lexical activation and syntactic operations are de-synchronized; that is, lexical access is too slow for normally fast-acting syntactic operations. This delay in lexical access leads to what appear to be syntactic comprehension deficits in aphasia. In the current study we further examined lexical activation during sentence comprehension in persons with aphasia by using unaccusative verbs. Unaccusative verbs are a type of intransitive verb with a single argument that is base generated in object position and displaced to the surface subject position, leaving behind a copy or trace (‘gap’) of the movement (see, for example, Burzio, 1986), as in:
1. The girl vanished
Thus there is a syntactic dependency between the two positions. When encountering sentences that contain syntactic dependencies (e.g., object relatives, Wh-questions) neurologically unimpaired individuals immediately reactivate the displaced argument at the gap (Shapiro et al., 1999; Love et al., 2008). In contrast to this immediate reactivation, prior findings indicate that neurologically unimpaired individuals do not reactivate the displaced argument in similar sentences with unaccusative verbs until 750ms downstream from the gap (Friedmann et al., 2008). This built-in delay observed with unaccusative verbs in neurologically healthy participants provides a unique opportunity to further examine lexical delays in individuals with Broca’s aphasia. Importantly, individuals with Broca’s aphasia may have unaccusative verb deficits. Previous research has found that persons with aphasia have difficulty producing unaccusative verbs. Offline truth-value judgment tasks with intransitive sentences containing unaccusative verbs do not reveal comprehension deficits (Lee & Thompson, 2004). However, in a sentence-picture matching task, McAllister et al. (2009) found lower accuracy for intransitive sentences that contained unaccusative verbs than transitive sentences. We entertain the following hypothesis: The delayed lexical access routines better synchronize with the delay of reactivating the argument of unaccusatives, suggesting that individuals with Broca’s aphasia should evince a pattern like that of unimpaired individuals. Alternatively, participants with Broca’s aphasia might show activation even further downstream from the gap, given that in other sentence constructions containing syntactic dependencies they exhibit a delayed pattern of reactivation compared to neurologically unimpaired individuals
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