The GRAAL high resolution BGO calorimeter and its energy calibration and monitoring system

We describe the electromagnetic calorimeter built for the GRAAL apparatus at the ESRF. Its monitoring system is presented in detail. Results from tests and the performance obtained during the first GRAAL experiments are given. The energy calibration accuracy and stability reached is a small fraction of the intrinsic detector resolution.Comment: 19 pages, 14 figures, submitted to Nuclear Instruments and Method

Differential cross section measurement of eta photoproduction on the proton from threshold to 1100 MeV

The differential cross section for the reaction p(gamma, eta p) has been measured from threshold to 1100 MeV photon laboratory energy. For the first time, the region of the S11(1535) resonance is fully covered in a photoproduction experiment and allows a precise extraction of its parameters at the photon point. Above 1000 MeV, S-wave dominance vanishes while a P-wave contribution is observed whose nature will have to be clarified. These high precision data together with the already measured beam asymmetry data will provide stringent constraints on the extraction of new couplings of baryon resonances to the eta meson.Comment: 10 pages, 5 figures, submitted to Phys. Letters B. Typos corrected. Some more information on the S11(1535) parameter

Eta photoproduction on the neutron at GRAAL: Measurement of the differential cross section

In this contribution, we will present our first preliminary measurement of the differential cross section for the reaction gamma+n->eta+n. Comparison of the reactions gamma+p->eta+p for free and bound proton (D2 target) will also be discussed.Comment: 6 pages, 4 figures, Proceedings of the 10th International Symposium on Meson-Nucleon Physics and the Structure of the Nucleon, August 29-September 4 2004, Beijing, Chin

Shedding New Light on Kaon-Nucleon/Nuclei Interaction and Its Astrophysical Implications with the AMADEUS Experiment at DAFNE

The AMADEUS experiment deals with the investigation of the low-energy kaon-nuclei hadronic interaction at the DA{\Phi}NE collider at LNF-INFN, which is fundamental to respond longstanding questions in the non-perturbative QCD strangeness sector. The antikaon-nucleon potential is investigated searching for signals from possible bound kaonic clusters, which would open the possibility for the formation of cold dense baryonic matter. The confirmation of this scenario may imply a fundamental role of strangeness in astrophysics. AMADEUS step 0 consisted in the reanalysis of 2004/2005 KLOE dataset, exploiting K- absorptions in H, 4He, 9Be and 12C in the setup materials. In this paper, together with a review on the multi-nucleon K- absorption and the particle identification procedure, the first results on the {\Sigma}0-p channel will be presented including a statistical analysis on the possible accomodation of a deeply bound stateComment: 6 pages, 2 figure, 1 table, HADRON 2015 conferenc

Lowering the Light Speed Isotropy Limit: European Synchrotron Radiation Facility Measurements

The measurement of the Compton edge of the scattered electrons in GRAAL facility in European Synchrotron Radiation Facility (ESRF) in Grenoble with respect to the Cosmic Microwave Background dipole reveals up to 10 sigma variations larger than the statistical errors. We now show that the variations are not due to the frequency variations of the accelerator. The nature of Compton edge variations remains unclear, thus outlining the imperative of dedicated studies of light speed anisotropy

Platelets and Hepatocellular Cancer: Bridging the Bench to the Clinics

Growing interest is recently being focused on the role played by the platelets in favoring hepatocellular cancer (HCC) growth and dissemination. The present review reports in detail both the experimental and clinical evidence published on this topic. Several growth factors and angiogenic molecules specifically secreted by platelets are directly connected with tumor progression and neo-angiogenesis. Among them, we can list the platelet-derived growth factor, the vascular endothelial growth factor, the endothelial growth factor, and serotonin. Platelets are also involved in tumor spread, favoring endothelium permeabilization and tumor cells\u2019 extravasation and survival in the bloodstream. From the bench to the clinics, all of these aspects were also investigated in clinical series, showing an evident correlation between platelet count and size of HCC, tumor biological behavior, metastatic spread, and overall survival rates. Moreover, a better understanding of the mechanisms involved in the platelet\u2013tumor axis represents a paramount aspect for optimizing both current tumor treatment and development of new therapeutic strategies against HCC

Unprecedented studies of the low-energy negatively charged kaons interactions in nuclear matter by AMADEUS

The AMADEUS experiment aims to provide unique quality data of $K^-$ hadronic interactions in light nuclear targets, in order to solve fundamental open questions in the non-perturbative strangeness QCD sector, like the controversial nature of the $\Lambda(1405)$ state, the yield of hyperon formation below threshold, the yield and shape of multi-nucleon $K^-$ absorption, processes which are intimately connected to the possible existence of exotic antikaon multi-nucleon clusters. AMADEUS takes advantage of the DA$\Phi$NE collider, which provides a unique source of monochromatic low-momentum kaons and exploits the KLOE detector as an active target, in order to obtain excellent acceptance and resolution data for $K^-$ nuclear capture on H, ${}^4$He, ${}^{9}$Be and ${}^{12}$C, both at-rest and in-flight. During the second half of 2012 a successful data taking was performed with a dedicated pure carbon target implemented in the central region of KLOE, providing a high statistic sample of pure at-rest $K^-$ nuclear interactions. For the future dedicated setups involving cryogenic gaseous targets are under preparation.Comment: 14 pages, 6 figure

Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAFNE

The study of the KbarN system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAFNE electron-positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with Z=1 and Z=2, taking advantage of the low-energy charged kaons from Phi-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon-nucleon interaction, measurements of Kp and of Kd are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: Y(K_tot)<0.0143 and Y(K_alpha)<0.0039 (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced.Comment: Accepted by Nuclear Physics

A new limit on the light speed isotropy from the GRAAL experiment at the ESRF

When the electrons stored in the ring of the European Synchrotron Radiation Facility (ESRF, Grenoble) scatter on a laser beam (Compton scattering in flight) the lower energy of the scattered electron spectra, the Compton Edge (CE), is given by the two body photon-electron relativistic kinematics and depends on the velocity of light. A precision measurement of the position of this CE as a function of the daily variations of the direction of the electron beam in an absolute reference frame provides a one-way test of Relativistic Kinematics and the isotropy of the velocity of light. The results of GRAAL-ESRF measurements improve the previously existing one-way limits, thus showing the efficiency of this method and the interest of further studies in this direction.Comment: Proceed. MG12 meeting, Paris, July, 200