29 research outputs found

    Transfer of Mathematical Knowledge: Series

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    The aim of this study is to explain students’ ability to transfer their knowledge about mathematical series to the problems that they encounter. The data of the study were obtained by using two different tests, namely “Problem Solving Test (PST)” and “Series Character Identification Test (SCT)” which were developed by the researchers. The study was conducted to third- grade students from department of elementary school mathematics education in the 2009-2010 academic year. In view of the analysis of the data, it was observed that the students experienced no difficulty in the SCT which required procedural knowledge. They experienced difficulty in the PST which required skill to transfer their knowledge about the series to the circumstances that they encounter. According to these results, it was determined that the students experienced difficulty in transforming real life problems to series and interpreting these problems

    Real-world efficacy and safety of Ledipasvir plus Sofosbuvir and Ombitasvir/Paritaprevir/Ritonavir +/- Dasabuvir combination therapies for chronic hepatitis C: A Turkish experience

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    Background/Aims: This study aimed to evaluate the real-life efficacy and tolerability of direct-acting antiviral treatments for patients with chronic hepatitis C (CHC) with/without cirrhosis in the Turkish population.Material and Methods: A total of 4,352 patients with CHC from 36 different institutions in Turkey were enrolled. They received ledipasvir (LDV) and sofosbuvir (SOF)+/- ribavirin (RBV) ombitasvir/paritaprevir/ritonavir +/- dasabuvir (PrOD)+/- RBV for 12 or 24 weeks. Sustained virologic response (SVR) rates, factors affecting SVR, safety profile, and hepatocellular cancer (HCC) occurrence were analyzed.Results: SVR12 was achieved in 92.8% of the patients (4,040/4,352) according to intention-to-treat and in 98.3% of the patients (4,040/4,108) according to per-protocol analysis. The SVR12 rates were similar between the treatment regimens (97.2%-100%) and genotypes (95.6%-100%). Patients achieving SVR showed a significant decrease in the mean serum alanine transaminase (ALT) levels (50.90 +/- 54.60 U/L to 17.00 +/- 14.50 U/L) and model for end-stage liver disease (MELD) scores (7.51 +/- 4.54 to 7.32 +/- 3.40) (p<0.05). Of the patients, 2 were diagnosed with HCC during the treatment and 14 were diagnosed with HCC 37.0 +/- 16.0 weeks post-treatment. Higher initial MELD score (odds ratio [OR]: 1.92, 95% confidence interval [CI]: 1.22-2.38; p=0.023]), higher hepatitis C virus (HCV) RNA levels (OR: 1.44, 95% CI: 1.31-2.28; p=0.038), and higher serum ALT levels (OR: 1.38, 95% CI: 1.21-1.83; p=0.042) were associated with poor SVR12. The most common adverse events were fatigue (12.6%), pruritis (7.3%), increased serum ALT (4.7%) and bilirubin (3.8%) levels, and anemia (3.1%).Conclusion: LDV/SOF or PrOD +/- RBV were effective and tolerable treatments for patients with CHC and with or without advanced liver disease before and after liver transplantation. Although HCV eradication improves the liver function, there is a risk of developing HCC.Turkish Association for the Study of The Liver (TASL

    Behçet hastalığında koklear ve vestibüler fonksiyonlar

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    TEZ809Tez (Uzmanlık) -- Çukurova Üniversitesi, Adana, 1990.Kaynakça (s. 29-34) var.34 s. ; 30 cm.

    Cinsel işlev bozuklukarında psikososyal etmenler

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    TEZ3309Tez (Uzmanlık) -- Çukurova Üniversitesi, Adana, 1999.Kaynakça (s. 49-53) var.vi, 65 s. ; 30 cm.

    Behavioural-systemic approach to couple therapy: A case report

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    Amaç: Davranışçı-sistemik eş terapileri, eşlerin birbirlerine daha iyi uyum sağlayabilmelerini ve ilişkilerinde daha esnek olabilmelerini hedefler. Bu temel hedeflere varabilmek için eşlerin uzlaşma becerilerini arttırmak, daha yapıcı tartışabilmelerini ve daha iyi iletişim kurabilmelerim sağlamak, bireysel sınır ve sorumlulukları göstermek ve eşlerin davranış repertuarlarını genişletebilmek gerekir. Hangi çifte hangi tür müdahalenin daha uygun olacağını belirlemekte bir rehber gibi kullanılabilen Müdahale Seçenekleri Çizelgesi (ALI-Alternative levels of intervention) temel hedeflere ulaşmada hangi müdahalenin seçileceği konusunda önemli bilgiler verir. Bu olgu sunumunda evlilik içi sorunların yanısıra eşlerden birinin depresyon tanısı ile etiketlendiği bir çiftin tedavisi sunulmuş ve tartışılmıştır.Behavioral -systemic approach to couple therapy aims a better adjustment of the partners to each other and greater flexibility in their interaction as the main goals. Ability to negotiate, better communication, to argue successfully; better acceptance of personal boundaries and individual responsibilty and a greater repertoire of responses are the elements of these goals. To achieve these goals, ALI (Alternative Levels of Intervention) seems to be a practical guide as part of the behavioral-systems approach. In this case report, we presented and discussed a couple having marital relationship problems as well as one being stigmatized as having depression
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