DECA: A new model for assessing the foliar uptake of atmospheric lead by vegetation, using Lactuca sativa as an example

In the context of peri-urban atmospheric pollution by industrial lead recycling emissions, metal can transfer to plant shoots. Home gardeners consuming their produce can therefore be exposed to metal pollution. The Human Health Risk Assessment Protocol (HHRAP) model from the United States Environmental Protection Agency (US EPA) classically used in risk assessment provides foliar metal uptake predictions for large farms but is not adapted to cultures in kitchen gardens. Thus, this study developed a new model, entitled “DECA”, which includes individually measured parameters and the washing of vegetables before human consumption. Results given by DECA and HHRAP models were compared with experimental measurements of lettuce. The data calculated by the DECA model were highly correlated with the measured values; the HHRAP model overestimates foliar lead uptake. Moreover, strong influences of factor of washing and time-dependent variations of loss coefficient were highlighted. Finally, the DECA model provided important risk assessment data regarding consumption of vegetables from kitchen gardens

Diversity-Multiplexing Tradeoff for the MIMO Static Half-Duplex Relay

In this work, we investigate the diversity-multiplexing tradeoff (DMT) of the multiple-antenna (MIMO) static half-duplex relay channel. A general expression is derived for the DMT upper bound, which can be achieved by a compress-and-forward protocol at the relay, under certain assumptions. The DMT expression is given as the solution of a minimization problem in general, and an explicit expression is found when the relay channel is symmetric in terms of number of antennas, i.e. the source and the destination have n antennas each, and the relay has m antennas. It is observed that the static half-duplex DMT matches the full-duplex DMT when the relay has a single antenna, and is strictly below the full-duplex DMT when the relay has multiple antennas. Besides, the derivation of the upper bound involves a new asymptotic study of spherical integrals (that is, integrals with respect to the Haar measure on the unitary group U(n)), which is a topic of mathematical interest in itself.Comment: 19 pages, 2 figures, submitted to the IEEE Transactions on Information Theor

Intensification or Diversification: Responses by Anti Health-Pass Entrepreneurs to French Government Announcements

We study the extent to which French entrepreneurs mobilized in an online collective action against the generalization of the health-pass policy in summer 2021. We document the dynamics of registrations on the website Animap.fr where entrepreneurs could claim they would not check the health-pass of their clients. We first note an over-representation of complementary and alternative medicine (CAM) practitioners among the mobilized people. We also suggest that professionals related to the touristic industry mobilized on the website. Second, we show that the government announcements led to an increase in the mobilization. However, they did not affect the diversity of the entrepreneurs joining the action. This lack of diversity may have restricted the pool of potential participants as well as limited the identification of the “public opinion” to the mobilization

An objective rationale for the choice of regularisation parameter with application to global multiple-frequency S -wave tomography

In a linear ill-posed inverse problem, the regularisation parameter (damping) controls the balance between minimising both the residual data misfit and the model norm. Poor knowledge of data uncertainties often makes the selection of damping rather arbit

Ethical thinking machines in surgery and the requirement for clinical leadership

No abstract available

Macro-Architectures in Spinal Cord Scaffold Implants Influence Regeneration

Abstract Biomaterial scaffold architecture has not been investigated as a tunable source of influence on spinal cord regeneration. This study compared regeneration in a transected spinal cord within various designed-macro-architecture scaffolds to determine if these architectures alone could enhance regeneration. Three-dimensional (3-D) designs were created and molds were built on a 3-D printer. Salt-leached porous poly(ε-caprolactone) was cast in five different macro-architectures: cylinder, tube, channel, open-path with core, and open-path without core. The two open-path designs were created in this experiment to compare different supportive aspects of architecture provided by scaffolds and their influence on regeneration. Rats received T8 transections and implanted scaffolds for 1 and 3 months. Overall morphology and orientation of sections were characterized by H&E, luxol fast blue, and cresyl violet staining. Borders between intact gray matter and non-regenerated defect were observed from GFAP immunolabeling. Nerve fibers and regenerating axons were identified with Tuj-1 immunolabeling. The open-path designs allowed extension of myelinated fibers along the length of the defect both exterior to and inside the scaffolds and maintained their original defect length up to 3 months. In contrast, the cylinder, tube, and channel implants had a doubling of defect length from secondary damage and large scar and cyst formation with no neural tissue bridging. The open-path scaffold architectures enhanced spinal cord regeneration compared to the three other designs without the use of biological factors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63279/1/neu.2007.0473.pd

Characterization and regulation of the expression of scyllatoxin (Leiurotoxin I) receptors in the human neuroblastoma cell line NB-OK 1

Abstract125I-[Tyr2]scyllatoxin allowed to label a single class of high-affinity receptors in membranes from the human neuroblastoma cell line NB-OK 1. The Kd of these receptors was 60 pM for scyllatoxin (Leiurotoxin I) and 20 pM for apamin and the Bmax was low (3.8 fmol/mg membrane protein). K+ increased toxin binding at low concentrations but exerted opposite effects at high concentrations. Ca2+, guanidinium and Na+ exerted only inhibitory effects on binding. Scyllatoxin binding sites were overexpressed 2.5-fold after a 24-h cell pretreatment with 2 mM butyrate. This effect was suppressed by cycloheximide