Digital and programmable economy applications: A smart cities congestion case by fuzzy sets

Currently, cities are facing great challenges such as the population growing, citizen wellbeing, externalities management or environmental deterioration. The search for solutions are making significant inroads into the incorporation of ICT in them and subsequent large-scale digitalization such as programmable economy (PE) applications, offering the possibility to develop new approaches over these issues, in particular which related to sustainability management. Operating under a fuzzy numbers methodology and FIS (Fuzzy Inference System), the present exploratory work shows a new approach to city urban congestion management by deploying PE applications, which include some disruptive inputs such as the Internet of value, blockchain/DLT (distributed ledger, technology), smarts contracts, digital assets and the monetization, all of this combined with the human motivation

Changes in iron metabolism and oxidative status in STZ-induced diabetic rats treated with bis(maltolato) oxovanadium(IV) as an antidiabetic agent

The role of vanadium as a micronutrient and hypoglycaemic agent has yet to be fully clarified. The present study was undertaken to investigate changes in the metabolism of iron and in antioxidant defences of diabetic STZ rats following treatment with vanadium. Four groups were examined: control; diabetic; diabetic treated with 1 mgV/day; and Diabetic treated with 3 mgV/day. The vanadium was supplied in drinking water as bis(maltolato) oxovanadium (IV) (BMOV). The experiment had a duration of five weeks. Iron was measured in food, faeces, urine, serum, muscle, kidney, liver, spleen, and femur. Superoxide dismutase, catalase, NAD(P)H: quinone-oxidoreductase-1 (NQO1) activity, and protein carbonyl group levels in the liver were determined. In the diabetic rats, higher levels of Fe absorbed, Fe content in kidney, muscle, and femur, and NQO1 activity were recorded, together with decreased catalase activity, in comparison with the control rats. In the rats treated with 3 mgV/day, there was a significant decrease in fasting glycaemia, Fe content in the liver, spleen, and heart, catalase activity, and levels of protein carbonyl groups in comparison with the diabetic group. In conclusion BMOV was a dose-dependent hypoglycaemic agent. Treatment with 3 mgV/day provoked increased Fe deposits in the tissues, which promoted a protein oxidative damage in the liver.The authors are grateful for support received from the Consejería de Innovación, Ciencia y Empresa, Andalusian Regional Government (Project P06-CTS-01435)

Sinorhizobium fredii Strains HH103 and NGR234 Form Nitrogen Fixing Nodules With Diverse Wild Soybeans (Glycine soja) From Central China but Are Ineffective on Northern China Accessions

Sinorhizobium fredii indigenous populations are prevalent in provinces of Central China whereas Bradyrhizobium species (Bradyrhizobium japonicum, B. diazoefficiens, B. elkanii, and others) are more abundant in northern and southern provinces. The symbiotic properties of different soybean rhizobia have been investigated with 40 different wild soybean (Glycine soja) accessions from China, Japan, Russia, and South Korea. Bradyrhizobial strains nodulated all the wild soybeans tested, albeit efficiency of nitrogen fixation varied considerably among accessions. The symbiotic capacity of S. fredii HH103 with wild soybeans from Central China was clearly better than with the accessions found elsewhere. S. fredii NGR234, the rhizobial strain showing the broadest host range ever described, also formed nitrogen-fixing nodules with different G. soja accessions from Central China. To our knowledge, this is the first report describing an effective symbiosis between S. fredii NGR234 and G. soja. Mobilization of the S. fredii HH103 symbiotic plasmid to a NGR234 pSym-cured derivative (strain NGR234C) yielded transconjugants that formed ineffective nodules with G. max cv. Williams 82 and G. soja accession CH4. By contrast, transfer of the symbiotic plasmid pNGR234a to a pSym-cured derivative of S. fredii USDA193 generated transconjugants that effectively nodulated G. soja accession CH4 but failed to nodulate with G. max cv. Williams 82. These results indicate that intra-specific transference of the S. fredii symbiotic plasmids generates new strains with unpredictable symbiotic properties, probably due to the occurrence of new combinations of symbiotic signals.España, Junta de Andalucía P11-CVI-7500España Ministerio de Economía y Competitividad BIO2016-78409-

Normativa de elaboración del Trabajo Final de Master: guía del estudiante

Normativa i procediment d'ajuda als estudiants, per l'elaboració del Treball Final de Màster (TFM) del Màster en Direcció d'Empreses de l'Esport de la UBREDICE (2014-15) 14-72

L'aprenentatge basat en el joc: aplicació a l'assignatura de Gestió de la Qualitat

L'objectiu d'aquest article és explicar l'experiència de creació i aplicació d'un joc de pregunta-resposta similar al Trivial Pursuit, però adaptant-lo al contingut de l'assignatura de Gestió de la Qualitat. S'intenta proporcionar a l'alumnat una metodologia d'aprenentatge diferent, més distesa i en equip, que li permeti interioritzar el coneixement de l'assignatura de manera més fàcil i entenedora. El joc s'ha creat modificant preguntes test multiopció de cursos anteriors a preguntes obertes. Els participants, que són 165 alumnes dels tres grups de l'assignatura de Gestió de la Qualitat dels graus d'Administració i Direcció d'Empreses i Empresa Internacional que duien a terme les activitats d'avaluació continuada, han valorat l'experiència com a molt positiva. Els resultats demostren que, tot i que l'alumnat està satisfet amb el joc i l'ha ajudat a interioritzar millor el coneixement de l'assignatura, només han treballat la competència de «treball en equip»; per tant, el joc no permet desenvolupar ni millorar les competències de l'assignatura, però sí l'aprenentatge. Aquest article és un dels primers que presenta una experiència d'aprenentatge basat en el joc en aquests graus

Coordination of subjects in the program as a formative activity of the multidisciplinary educational team for the degree in Pharmacy

La Universidad de Granada, dentro del Plan Estratégico y el Contrato Programa 2007-2011 de las Universidades Públicas de Andalucía puso en marcha la convocatoria de apoyo a la formación del profesorado principiante y mejora de la docencia por el Vicerrectorado para la Garantía de la Calidad (http://calidad.ugr.es/pages/secretariados/form_apoyo_calidad/apoyo_formacion_principiante/convoca toria). En el proyecto participan 15 profesores, 5 profesores experimentados y 10 profesores noveles de seis departamentos diferentes.. Entre los objetivos se incluye la optimización de la actividad docente de profesorado principiante. En este sentido se estudió la situación en el nuevo plan de estudio de Grado en Farmacia de las asignaturas que dichos profesores impartimos, así como la relación entre ellas y la posible existencia de solapamientos de contenidos docentes. Las fichas docentes muestran ciertos solapamientos de competencias y carencias en algunos casos. Esto supuso una revisión exhaustiva para llevar a cabo una correcta coordinación entre los profesores que le permita al alumnado un aprendizaje organizado y coherente.The University of Granada, inside the Strategic Plan and the Contract Program 2007-2011 of the Public Universities of Andalusia started a public call to improve the formation of young lecturers and the teaching activity (http://calidad.ugr.es/pages/secretariados/form_apoyo_calidad/apoyo_formacion_principiante/convoca toria). In the project there take part 15 lecturers, 5 experienced and 10 young lecturers from six different departments. Within the objectives it is included the optimisation of the teaching activity of young lecturers. In this sense, it was studied the situation of the subjects that the above mentioned lecturers give within the new degree in Pharmacy, as well as the relation between they and the possible existence of any overlapping in the contents. The teaching contents showed the existence of certain overlapping within competences and deficiencies in some cases. This supposed an exhaustive review to carry out the correct coordination between the different lecturers so that it will allow the organized and coherent learning of the students

Transcriptomic studies of the effect of nod gene-inducing molecules in rhizobia: Different weapons, one purpose

Simultaneous quantification of transcripts of the whole bacterial genome allows the analysis of the global transcriptional response under changing conditions. RNA-seq and microarrays are the most used techniques to measure these transcriptomic changes, and both complement each other in transcriptome profiling. In this review, we exhaustively compiled the symbiosis-related transcriptomic reports (microarrays and RNA sequencing) carried out hitherto in rhizobia. This review is specially focused on transcriptomic changes that takes place when five rhizobial species, Bradyrhizobium japonicum (=diazoefficiens) USDA 110, Rhizobium leguminosarum biovar viciae 3841, Rhizobium tropici CIAT 899, Sinorhizobium (=Ensifer) meliloti 1021 and S. fredii HH103, recognize inducing flavonoids, plant-exuded phenolic compounds that activate the biosynthesis and export of Nod factors (NF) in all analysed rhizobia. Interestingly, our global transcriptomic comparison also indicates that each rhizobial species possesses its own arsenal of molecular weapons accompanying the set of NF in order to establish a successful interaction with host legumes.Ministerio de Economía y Competitividad BIO2016-78409-R, AGL2016-77163-

A transcriptomic analysis of the effect of genistein on Sinorhizobium fredii HH103 reveals novel rhizobial genes putatively involved in symbiosis

Sinorhizobium fredii HH103 is a rhizobial soybean symbiont that exhibits an extremely broad host-range. Flavonoids exuded by legume roots induce the expression of rhizobial symbiotic genes and activate the bacterial protein NodD, which binds to regulatory DNA sequences called nod boxes (NB). NB drive the expression of genes involved in the production of molecular signals (Nod factors) as well as the transcription of ttsI, whose encoded product binds to tts boxes (TB), inducing the secretion of proteins (effectors) through the type 3 secretion system (T3SS). In this work, a S. fredii HH103 global gene expression analysis in the presence of the flavonoid genistein was carried out, revealing a complex regulatory network. Three groups of genes differentially expressed were identified: i) genes controlled by NB, ii) genes regulated by TB, and iii) genes not preceded by a NB or a TB. Interestingly, we have found differentially expressed genes not previously studied in rhizobia, being some of them not related to Nod factors or the T3SS. Future characterization of these putative symbiotic-related genes could shed light on the understanding of the complex molecular dialogue established between rhizobia and legumes.España, Ministerio de Economía y Competitividad BIO2011-30229-C01España, Ministerio de Economía y Competitividad AGL2012-38831Junta de Andalucía, P11-CVI-7050Junta de Andalucía P11-CVI-750

Normativa de seguiment i tutoria del Treball Final de Màster – guia dels tutors –

En el procés d’elaboració del Treball Final de Màster (TFM) la supervisió i guia del tutor/a designat, per a realitzar correctament aquest treball esdevé una ajuda fonamental. El tutor/a orienta, fa el seguiment del projecte i assessora l’estudiant en el temps de treball, el motiva i garanteix la qualitat del treball per poder passar a la seva defensa i avaluació

Normativa d’avaluació del Treball Final de Màster – guia del tribunal d’avaluació–

El procés d'avaluació del Treball Final de Màster (TFM) és la darrera etapa d'aquesta singular assignatura que és el TFM. És el moment d'avaluar el treball realitzat per un tribunal extern. Cal tenir en compte les opinions dels professors/es que han realitzat les tutories, alhora que pensem que no ha de condicionar el procés d'avaluació global que realitza el tribunal