1,298 research outputs found
Using Recovery Coaches in Substance Use Disorder Treatment
A Recovery Coach is a person who helps remove the personal and environmental obstacles to recovery, links the newly recovering person to the recovering community and serves as a personal guide and mentor in the management of personal and family recovery. In this webinar you will learn what motivational interviewing is and how it aids in the change process and communicates acceptance. Rich and Rob will present an overview of the Recovery Coaching program at the University of Massachusetts Medical Center. They will also share the data they have collected from their program about the use of recovery coaching in the treatment of substance use disorder.
Learning Objectives: Learn about the UMassMemorial Medical Center’s Recovery Coaching program as a method to treat substance use disorder. Learn what motivational interviewing is and how to use motivational interviewing in goal-centered, and client-centered situations. Learn what is measured when evaluating whether recovery coaching is a successful treatment for substance use disorder. Understand the data that has been collected about the success of the Recovery Coaching program at the UMassMemorial Medical Center
A clinical study of solitary nodule of thyroid
BACKGROUND AND OBJECTIVES:
Solitary nodule of thyroid has increased in incidence in the present day as
compared to two decades before. Because of possibility of malignancy, some
clinicians especially those in surgical subspecialties recommended that all
nodules have to be removed. This study aimed to determine the propotion of
solitary nodule of thyroid in general population and in relation to age and sex, the
propotion of solitary nodule of thyroid turning out to be multi-nodular goiter, the
propotion of euthyroid, hyperthyroid or hypothyroid states in patients presenting
with solitary nodule of thyroid, to study the role of FNAC in the management of
solitary nodule of thyroid and to determine the incidence of neoplastic and nonneoplastic
conditions as a cause of solitary nodule of thyroid in Govt.
Royapettah Hospital, Chennai.
METHODS:
This prospective study includes 50 patients, presenting in Govt. Royapettah
Hospital, Chennai who were clinically diagnosed as solitary nodule of thyroid
between November 2014 to September 2015. All patients were admitted and were
subjected to thyroid profile, USG and FNAC. All patients were operated
appropriately depending on the FNAC report.
Histopathological examination of the operated specimen was done for all
the patients. Depending on the histo-pathological report appropriate postoperative
therapies were administered to all the patients and all the patients were followed
up appropriately.
RESULTS:
Commonest presentation of solitary thyroid nodule was asymptomatic. The
peak incidence of solitary nodule was observed in 3rd to 5th decade, constituting
60% of the cases studied. Females predominated in number over males in
occurrence of solitary nodule in ratio of 1:5.25. 33% of all clinically solitary
nodule turned out to be multi-nodular goiter. The common causes of solitary
nodule was MNG (26%),follicular adenoma (24%),adenomatous goiter(24%).
95% 0f cases presented with euthyroid state. Incidence of malignancy in solitary
thyroid nodule was 18%. Male to female ratio in case of malignant nodule
was1:5. Incidence of carcinoma in males presenting as solitary nodule was
higher (16.67%) compared to that of females (10.20%). The most common
cause of malignancy was papillary carcinoma (55%) followed by follicular
carcinoma (45%).
INTERPRETATION AND CONCLUSION:
Solitary nodule of thyroid is more common in 3rd to 5th decades. Solitary
nodule of thyroid are more common in females. Most of the patients presenting
with solitary nodule of thyroid are euthyroid and only a small percentage of
patient with toxicity or hypothyroidism . USG can be accurately used to detect
patients with multinodulary goiter who clinically present as solitary nodule of
thyroid. Common causes of solitary nodule of thyroid are MNG, follicular
adenoma and adenomatous goiter. Incidence of malignancy in male patients
presenting with solitary nodule of thyroid is more when compared to
female. The most common cause of malignancy in solitary nodule is papillary
carcinoma followed by follicular carcinoma
Unmanned Aircraft System (UAS) Delegation of Separation in NextGen Airspace
The purpose of this study was to determine the feasibility of unmanned aircraft systems (UAS) performing delegated separation in the national airspace system (NAS). Delegated separation is the transfer of responsibility for maintaining separation between aircraft or vehicles from air navigation service providers to the relevant pilot or flight operator. The effects of delegated separation and traffic display information level were collected through performance, workload, and situation awareness measures. The results of this study show benefits related to the use of conflict detection alerts being shown on the UAS operator's cockpit situation display (CSD), and to the use of full delegation. Overall, changing the level of separation responsibility and adding conflict detection alerts on the CSD was not found to have an adverse effect on performance as shown by the low amounts of losses of separation. The use of conflict detection alerts on the CSD and full delegation responsibilities given to the UAS operator were found to create significantly reduced workload, significantly increased situation awareness and significantly easier communications between the UAS operator and air traffic controller without significantly increasing the amount of losses of separation
Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals.
We explored the possible augmenting effect of traumatic brain injury (TBI) history on HIV (human immunodeficiency virus) associated neurocognitive complications. HIV-infected participants with self-reported history of definite TBI were compared to HIV patients without TBI history. Groups were equated for relevant demographic and HIV-associated characteristics. The TBI group evidenced significantly greater deficits in executive functioning and working memory. N-acetylaspartate, a putative marker of neuronal integrity, was significantly lower in the frontal gray matter and basal ganglia brain regions of the TBI group. Together, these results suggest an additional brain impact of TBI over that from HIV alone. One clinical implication is that HIV patients with TBI history may need to be monitored more closely for increased risk of HIV-associated neurocognitive disorder signs or symptoms
Characterization of woodstove briquettes from torrefied biomass and coal
peer-reviewedUsing waste biomass materials offers the potential to reduce the greenhouse gas emissions from fossil fuels. Torrefaction is very useful for improving the fuel properties of biomass in order to better match those of coal. The aim of this work is to compare the properties of torrefied low quality biomass briquettes against coal equivalents. The composition of the briquettes was characterized by 13C CP/MAS, proximate analysis, and X-ray diffraction and the results were compared with equilibrium calculations. In addition to these techniques, we report for the first time on the use of XμCT for characterizing such materials. The XμCT analysis showed that the briquette structure contains carbon, binder and inorganic matter, with quartz retained from the original feedstock in torrefied biomass and coal briquettes. The CO2 reactivity of pulverized briquettes was investigated by thermogravimetric analysis. Results showed that the inorganic matter influences the reactivity less than the organic composition and porosity. Importantly from a technological standpoint, the increase in binder concentration and replacement of starch with resin binder did not influence the reactivity and calorific value of a pulverized briquette
Sleep abnormalities in the synaptopathies—SYNGAP1-related intellectual disability and Phelan–McDermid syndrome
Neurodevelopmental disorders are frequently associated with sleep disturbances. One class of neurodevelopmental disorders, the genetic synaptopathies, is caused by mutations in genes encoding proteins found at the synapse. Mutations in these genes cause derangement of synapse development and function. We utilized a validated sleep instrument, Children’s Sleep Habits Questionnaire (CSHQ) to examine the nature of sleep abnormalities occurring in individuals with two synaptopathies—Phelan–McDermid syndrome (PMD) (N = 47, male = 23, female = 24, age 1–46 years) and SYNGAP1-related intellectual disability (SYNGAP1-ID) (N = 64, male = 31, female = 33, age 1–64 years), when compared with unaffected siblings (N = 61, male = 25, female = 36, age 1–17 years). We found that both PMD and SYNGAP1-ID have significant sleep abnormalities with SYNGAP1-ID having greater severity of sleep disturbance than PMD. In addition, sleep disturbances were more severe for PMD in individuals 11 years and older compared with those less than 11 years old. Individuals with either disorder were more likely to use sleep aids than unaffected siblings. In conclusion, sleep disturbances are a significant phenotype in the synaptopathies PMD and SYNGAP1-ID. Improved sleep is a viable endpoint for future clinical trials for these neurodevelopmental disorders
Measurement of the hadronic activity in events with a Z and two jets and extraction of the cross section for the electroweak production of a Z with two jets in pp collisions at s√=7 TeV
This is the publisher's version, also available electronically from http://link.springer.com/article/10.1007%2FJHEP10%282013%29062.The first measurement of the electroweak production cross section of a Z boson with two jets (Zjj) in pp collisions at s√=7 TeV is presented, based on a data sample recorded by the CMS experiment at the LHC with an integrated luminosity of 5 fb(−1). The cross section is measured for the ℓℓjj (ℓ = e, μ) final state in the kinematic region m(ℓℓ) > 50 GeV, m(jj) > 120 GeV, transverse momenta p(j)(T)>25 GeV and pseudorapidity |η(j)| < 4.0. The measurement, combining the muon and electron channels, yields σ = 154 ± 24 (stat.) ± 46 (exp. syst.) ± 27 (th. syst.) ± 3 (lum.) fb, in agreement with the theoretical cross section. The hadronic activity, in the rapidity interval between the jets, is also measured. These results establish an important foundation for the more general study of vector boson fusion processes, of relevance for Higgs boson searches and for measurements of electroweak gauge couplings and vector boson scattering
CFD Simulations of Supersonic Highly Swirling Flow Exiting a Turbine Vane Row Compared with Experimental Observations
Marshall Space Flight Center (MSFC) has been heavily involved in developing the J2-X engine. The Center has been testing a Work Horse Gas Generator (WHGG) to supply gas products to J2-X turbine components at realistic flight-like operating conditions. Three-dimensional time accurate CFD simulations and analytical fluid analysis have been performed to support WHGG tests at MSFC. The general purpose CFD program LOCI/Chem was utilized to simulate flow of products from the WHGG through a turbine manifold, a stationary row of turbine vanes, into a Can and orifice assembly used to control the back pressure at the turbine vane row and finally through an aspirator plate and flame bucket. Simulations showed that supersonic swirling flow downstream of the turbine imparted a much higher pressure on the Can wall than expected for a non-swirling flow. This result was verified by developing an analytical model that predicts wall pressure due to swirling flow. The CFD simulations predicted that the higher downstream pressure would cause the pressure drop across the nozzle row to be approximately half the value of the test objective. With CFD support, a redesign of the Can orifice and aspirator plate was performed. WHGG experimental results and observations compared well with pre-test and post-test CFD simulations. CFD simulations for both quasi-static and transient test conditions correctly predicted the pressure environment downstream of the turbine row and the behavior of the gas generator product plume as it exited the WHGG test article, impacted the flame bucket and interacted with the external environment
Driver Persistence, Safety and Older Adult Self-efficacy: Addressing Driving Challenges Using Innovative Multimodal Communication Concepts
New assisted driving technology provides a solution to enabling driver persistence while also addressing older adult fitness to drive issues. The proposed driver assistance system follows a detailed literature review, an analysis of secondary data, and the specification of a solution using human machine interaction (HMI) design methods. Overall, the assisted driving concept follows from a principled/ethical perspective in relation to promoting self-efficacy and enablement for older adults. The system is conceptualized as a supportive friend or ‘co-pilot’. It is argued that the use of new car-based sensors, along with machine learning intelligence and novel multimodal HMI communication methods will enable driver persistence while also promoting older adult self-efficacy and positive ageing
Shuttle Ground Support Equipment (GSE) T-0 Umbilical to Space Shuttle Program (SSP) Flight Elements Consultation
The NASA Engineering and Safety Center (NESC) was tasked with assessing the validity of an alternate opinion that surfaced during the investigation of recurrent failures at the Space Shuttle T-0 umbilical interface. The most visible problem occurred during the Space Transportation System (STS)-112 launch when pyrotechnics used to separate Solid Rocket Booster (SRB) Hold-Down Post (HDP) frangible nuts failed to fire. Subsequent investigations recommended several improvements to the Ground Support Equipment (GSE) and processing changes were implemented, including replacement of ground-half cables and connectors between flights, along with wiring modifications to make critical circuits quad-redundant across the interface. The alternate opinions maintained that insufficient data existed to exonerate the design, that additional data needed to be gathered under launch conditions, and that the interface should be further modified to ensure additional margin existed to preclude failure. The results of the assessment are contained in this report
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