381 research outputs found

    Bildung nach Dreeben

    Full text link
    "An den Begriff der Bildung haben sich in mehr als zweihundert Jahren so viele Leistungserwartungen angelagert, dass er fast nur noch historisch und als Symbol ungelöster Probleme oder zu kompakt gestellter Fragen brauchbar scheint. ... Gibt es trotz dieser verfahrenen Lage noch gute Gründe, den Bildungsbegriff zu verwenden? Man kann auch umgekehrt fragen: Wo liegen die Grenzen einer Theorietradition, die von vornherein zum Begriff der Bildung in Distanz gegangen ist?" Mit dieser Frage bezieht sich der Autor auf die soziologische Theorietradition. "Denn anstatt von Bildung zu sprechen, verwenden Soziologen zur Analyse dessen, was in Schulen und Familien geschieht, zumeist die Unterscheidung von Erziehung und Sozialisation." Die Sozialisationstheorie des Unterrichts behandelt der Autor am Beispiel von Robert A. Dreeben. (DIPF/Orig./Un

    Temporal Evolution Of Universal Performance Indicators For Academic Publication

    No full text
    We show universal behaviour for two indicators of the quality of publications taken from two different data sets, papers from a single institution and those on arXiv. We demonstrate this universality for different years and subjects. This distribution is well fitted by a lognormal with a variance of around 1.3, consistent with Radicchi et al (2008). We will also discuss the evolution over time of our measures describing the data and note that simple models do not have the correct temporal behaviour for our parameters. Based on arXiv:1110.3271 with additional new material. Poster given at ECCS 201

    Die Nacht im Menschen - Hegels "Phänomenologie des Geistes": Auszug aus "Hegels Welt" von Jürgen Kaube

    Get PDF

    Hass im Netz: Vorabdruck aus "Die gespaltene Gesellschaft" von Jürgen Kaube und André Kieserling

    Get PDF
    Jürgen Kaube und André Kieserling: Die gespaltene Gesellschaft. Berlin: Rohwolt Berlin 2022. 978-3-7371-0148-

    Nociception-specific blink reflex : pharmacology in healthy volunteers

    Get PDF
    Background: The physiology and pharmacology of activation or perception of activation of pain-coding trigeminovascular afferents in humans is fundamental to understanding the biology of headache and developing new treatments. Methods: The blink reflex was elicited using a concentric electrode and recorded in four separate sessions, at baseline and two minutes after administration of ramped doses of diazepam (final dose 0.07 mg/kg), fentanyl (final dose 1.11 mu g/kg), ketamine (final dose 0.084 mg/kg) and 0.9 % saline solution. The AUC (area under the curve, mu V*ms) and the latency (ms) of the ipsi- and contralateral R2 component of the blink reflex were calculated by PC-based offline analysis. Immediately after each block of blink reflex recordings certain psychometric parameters were assessed. Results: There was an effect due to DRUG on the ipsilateral (F-3,F-60 = 7.3, P < 0.001) AUC as well as on the contralateral (F-3,F-60 = 6.02, P < 0.001) AUC across the study. A significant decrement in comparison to placebo was observed only for diazepam, affecting the ipsilateral AUC. The scores of alertness, calmness, contentedness, reaction time and precision were not affected by the DRUG across the sessions. Conclusion: Previous studies suggest central, rather than peripheral changes in nociceptive trigeminal transmission in migraine. This study demonstrates a robust effect of benzodiazepine receptor modulation of the nociception specific blink reflex (nBR) without any mu-opiate or glutamate NMDA receptor component. The nociception specific blink reflex offers a reproducible, quantifiable method of assessment of trigeminal nociceptive system in humans that can be used to dissect pharmacology relevant to primary headache disorders

    Pain Ratings, Psychological Functioning and Quantitative EEG in a Controlled Study of Chronic Back Pain Patients

    Get PDF
    <div><h3>Objectives</h3><p>Several recent studies report the presence of a specific EEG pattern named Thalamocortical Dysrhythmia (TCD) in patients with severe chronic neurogenic pain. This is of major interest since so far no neuroscientific indicator of chronic pain could be identified. We investigated whether a TCD-like pattern could be found in patients with moderate chronic back pain, and we compared patients with neuropathic and non-neuropathic pain components. We furthermore assessed the presence of psychopathology and the degree of psychological functioning and examined whether the strength of the TCD-related EEG markers is correlated with psychological symptoms and pain ratings.</p> <h3>Design</h3><p>Controlled clinical trial with age and sex matched healthy controls.</p> <h3>Methods</h3><p>Spontaneous EEG was recorded in 37 back pain patients and 37 healthy controls.</p> <h3>Results</h3><p>We were not able to observe a statistically significant TCD effect in the EEG data of the whole patient group, but a subsample of patients with evidence for root damage showed a trend in this direction. Pain patients showed markedly increased psychopathology. In addition, patients' ratings of pain intensity within the last 1 to 12 months showed strong correlations with EEG power, while psychopathology was correlated to the peak frequency.</p> <h3>Conclusion</h3><p>Out of several possible interpretations the most likely conclusion is that only patients with severe pain as well as root lesions with consecutive thalamic deafferentation develop the typical TCD pattern. Our primary method of defining ‘neuropathic pain’ could not reliably determine if such a deafferentation was present. Nevertheless the analysis of a specific subsample as well as correlations between pain ratings, psychopathology and EEG power and peak frequency give some support to the TCD concept.</p> <h3>Trial Registration</h3><p>ClinicalTrials.gov <a href="http://clinicaltrials.gov/ct2/show/NCT00744575">NCT00744575</a></p> </div

    Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception

    Full text link
    • …
    corecore