An EMG Keyboard for Forearm Amputees

A high-efficiency, easy-to-use input device is not only important for data entry but also for human-computer interaction. To date, there has been little research on input devices with many degrees of freedom (DOF) that can be used by the handicapped. This paper presents the development of an electromyography (EMG)-based input device for forearm amputees. To overcome the difficulties in analysing EMG and realising high DOF from biosignals, the following were integrated: (1) an online learning method to cope with nonlinearity and the individual difference of EMG signals; (2) a smoothing algorithm to deal with noisy recognition results and transition states; and (3) a modified Huffman coding algorithm to generate the optimal code, taking expected error and input efficiency into consideration. Experiments showed the validity of the system and the possibility for development of a quiet, free-posture (no postural restriction) input device with many DOF for users, including forearm amputees

Constitutive Expression of AID Leads to Tumorigenesis

Genome stability is regulated by the balance between efficiencies of the repair machinery and genetic alterations such as mutations and chromosomal rearrangements. It has been postulated that deregulation of class switch recombination (CSR) and somatic hypermutation (SHM), which modify the immunoglobulin (Ig) genes in activated B cells, may be responsible for aberrant chromosomal translocations and mutations of non-Ig genes that lead to lymphocyte malignancy. However, the molecular basis for these genetic instabilities is not clearly understood. Activation-induced cytidine deaminase (AID) is shown to be essential and sufficient to induce both CSR and SHM in artificial substrates in fibroblasts as well as B cells. Here we show that constitutive and ubiquitous expression of AID in transgenic mice caused both T cell lymphomas and dysgenetic lesions of epithelium of respiratory bronchioles (micro-adenomas) in all individual mice. Point mutations, but not translocations, were massively introduced in expressed T cell receptor (TCR) and c-myc genes in T lymphoma cells. The results indicate that AID can mutate non-Ig genes including oncogenes, implying that aberrant AID expression could be a cause of human malignancy

A Shock-Induced Pair of Superbubbles in the High-Redshift Powerful Radio Galaxy MRC 0406-244

We present new optical spectroscopy of the high-redshift powerful radio galaxy MRC 0406$-$244 at redshift of 2.429. We find that the two extensions toward NW and SE probed in the rest-frame ultraviolet image are heated mainly by the nonthermal continuum of the active galactic nucleus. However, each extension shows a shell-like morphology, suggesting that they are a pair of superbubbles induced by the superwind activity rather than by the interaction between the radio jet and the ambient gas clouds. If this is the case, the intense starburst responsible for the formation of superbubbles could occur $\sim 1 \times 10^9$ yr ago. On the other hand, the age of the radio jets may be of the order of $\sim 10^6$ yr, being much shorter than the starburst age. Therefore, the two events, i.e., the starburst and the radio-jet activities, are independent phenomena. However, their directions of the expanding motions could be governed by the rotational motion of the gaseous component in the host galaxy. This idea appears to explain the alignment effect of MRC 0406$-$244.Comment: 4 pages (emulateapj.sty), Fig. 1 (jpeg) + Fig.2 (eps). Accepted for publications in ApJ (Letters

Industrial Technology Capabilities and Policies in Asian Developing Countries

It has been increasingly recognized in recent years that industrial development is the best strategy that a developing country can adopt to achieve rapid economic progress. It has also been recognized that a key to rapid industrialization can be found in a country’s progress in technological capability. The term technology is commonly used to mean a collection of production techniques, know-how and skills which transform inputs into outputs. Thus, industrial technology is the practical application of technological knowledge in producing marketable goods. Technological capabilities include the ability to acquire (or select) imported or indigenous technologies, assimilate or adapt new technologies, disseminate new technical knowledge, and improve existing production processes and develop new technologies through investment in research and development (R&D)

A SYSTEM OF INPUT-OUTPUT ACCOUNTS FOR OKINAWA

Abstract not availabl