389 research outputs found

    User behaviour analysis and personalized TV content recommendation

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    Nowadays, there are many channels and television (TV) programs available, and when the viewer is confronted with this amount of information has difficulty in deciding which wants to see. However, there are moments of the day that viewers see always the same channels or programs, that is, viewers have TV content consumption habits. The aim of this paper was to develop a recommendation system that to be able to recommend TV content considering the viewer profile, time and weekday. For the development of this paper, were used Design Science Research (DSR) and Cross Industry Standard Process for Data Mining (CRISP-DM) methodologies. For the development of the recommendation model, two approaches were considered: a deterministic approach and a Machine Learning (ML) approach. In the ML approach, K-means algorithm was used to be possible to combine STBs with similar profiles. In the deterministic approach the behaviors of the viewers are adjusted to a profile that will allow you to identify the content you prefer. Here, recommendation system analyses viewer preferences by hour and weekday, allowing customization of the system, considering your historic, recommending what he wants to see at certain time and weekday. ML approach was not used due to amount of data extracted and computational resources available. However, through deterministic methods it was possible to develop a TV content recommendation model considering the viewer profile, the weekday and the hour. Thus, with the results it was possible to understand which viewer profiles where the ML can be used.COMPETE: POCI-01-0145-FEDER-007043 and FCT (Fundação para a CiĂȘncia e Tecnologia) within the Project Scope: UID/CEC/00319/2013 and was developed in partnership with AlticeLab

    Social media engagement and organic post effectiveness: A roadmap for increasing the effectiveness of social media use in hospitality industry

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    The present study assessed the social media use behavior of luxury hospitality facilities and offers suggestions to improve organic post effectiveness. All five-star tourism facilities operating in Turkey were incorporated into the study and publicly available post data on Facebook accounts of 441 facilities (out of a total of 612) were examined in the high tourist season (August) for one month. Data on 2,012 Facebook posts were obtained manually and filtered down to 1,847. The collected post data were subsequently coded using a content analysis form and analyzed via ordinal regression. The results highlighted the positive effects of interactive content and vivid content as well as the significance of the content type in achieving higher interaction among followers. The facility location and category (hotel, holiday village, thermal hotel) also emerged as significant factors affecting follower interactions

    Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq

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    Mesenchymal stem cells (MSC) are capable of multipotent differentiation into connective tissues and as such are an attractive source for autologous cell-based regenerative medicine and tissue engineering. Epigenetic mechanisms, like DNA methylation, contribute to the changes in gene expression in ageing. However there was a lack of sufficient knowledge of the role that differential methylation plays during chondrogenic, osteogenic and tenogenic differentiation from ageing MSCs. This study undertook genome level determination of the effects of DNA methylation on expression in engineered tissues from chronologically aged MSCs. We compiled unique DNA methylation signatures from chondrogenic, osteogenic, and tenogenic engineered tissues derived from young; n = 4 (21.8 years ± 2.4 SD) and old; n = 4 (65.5 years±8.3SD) human MSCs donors using the Illumina HumanMethylation 450 Beadchip arrays and compared these to gene expression by RNA sequencing. Unique and common signatures of global DNA methylation were identified. There were 201, 67 and 32 chondrogenic, osteogenic and tenogenic age-related DE protein-coding genes respectively. Findings inferred the nature of the transcript networks was predominantly for ‘cell death and survival’, ‘cell morphology’, and ‘cell growth and proliferation’. Further studies are required to validate if this gene expression effect translates to cell events. Alternative splicing (AS) was dysregulated in ageing with 119, 21 and 9 differential splicing events identified in chondrogenic, osteogenic and tenogenic respectively, and enrichment in genes associated principally with metabolic processes. Gene ontology analysis of differentially methylated loci indicated age-related enrichment for all engineered tissue types in ‘skeletal system morphogenesis’, ‘regulation of cell proliferation’ and ‘regulation of transcription’ suggesting that dynamic epigenetic modifications may occur in genes associated with shared and distinct pathways dependent upon engineered tissue type. An altered phenotype in engineered tissues was observed with ageing at numerous levels. These changes represent novel insights into the ageing process, with implications for stem cell therapies in older patients. In addition we have identified a number of tissue-dependant pathways, which warrant further studies

    A Blockchain-Based Approach Towards Overcoming Financial Fraud in Public Sector Services

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    In financial markets it is common for companies and individuals to invest into foreign companies. To avoid the double taxation of investors on dividend payment - both in the country where the profit is generated as well as the country of residence - most governments have entered into bilateral double taxation treaties, whereby investors can claim a tax refund in the country where the profit is generated. Due to easily forgeable documents and insufficient international exchange of information between tax authorities, investors illegitimately apply for these tax returns causing an estimated damage of 1.8 billion USD, for example, in Denmark alone. This paper assesses the potential of a blockchain database to provide a feasible solution for overcoming this problem against the backdrop of recent advances in the public sector and the unique set of blockchain capacities. Towards this end, we develop and evaluate a blockchain-based prototype system aimed at eliminating this type of tax fraud and increasing transparency regarding the flow of dividends. While the prototype is based on the specific context of the Danish tax authority, we discuss how it can be generalized for tracking international and interorganizational transactions

    Steps towards online monitoring systems and interoperability

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    In the health area, there is, on a daily basis, an enormous amount of data being produced and disseminated. The fast-growing amount of collected data and the rich knowledge, possibly life-saving, that could be extracted from these data has demanded the search of new ways to ensure the reliability and availability of the information with an emphasis on the efficient use of information technology tools. Although the main focus of the information systems is the health professionals who contact directly with the patient, it is also imperative to have tools for the background of the health units (information services, managers of systems, etc.). The main purpose of this work is the development of an innovative and interactive web platform for the daily monitoring of the web services activities of a Portuguese hospital, Centro Hospitalar do Porto (CHP). This platform is a web application developed in React that aims to ensure the correct functioning of the web services, that are responsible for numerous tasks within the hospital environment, and which failure could result in disastrous consequences, both for the health institution and for the patients. The development of the web application followed the six stages of the Design Science Research (DSR) methodology and was submitted to the Strengths Weaknesses Opportunities and Threats (SWOT) analysis, which results were considered optimistic.This work has been supported by FCT – Fundação para a CiĂȘncia e Tecnologia within the Project Scope: UID/CEC/00319/201

    TrivPlat - A monitoring, management and evaluation tool for electronic public procurement

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    Bad decisions in public procurement processes have two negative effects: price increase of public goods and services with an impact on public expenditure, and adversely effects on competition, with the negative result of loss of efficiency and social welfare. Electronic public procurement (EPP) has been considered an important tool for promoting competition, simplifying and ensuring transparency in decision-making processes, thus ensuring significant time and money gains. In Portugal, EPP replaced paper-based pre-contractual procedures for communication and processing based on information technologies and systems. Interested in this phenomenon, the authors of this paper structured the TrivPlat project, a tool of free access for monitoring, managing and evaluating electronic public procurement. This paper aims to present the TrivPlat project and its contributions to the discussion about additional efforts needed to be implemented in order to efficiently promote a more transparent and accountable governance, in the defense of public interest.This work is funded by FEDER funds through the Operational Program for Competitiveness Factors -COMPETE and National Funds through FCT -Foundation for Science and Technology under the Project: FCOMP-01-0124-FEDER-022674 and PEst-OE/CJP/UI0758/2013-1

    ON COMPUTER SIMULATION AS A COMPONENT IN INFORMATION SYSTEMS RESEARCH

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    Computer simulation is widely regarded as a useful activity during various phases of research. However, depending on its context, the meaning, definition, and focus of the term can vary: In traffic planning, for example, simulation is used to determine useful configurations of a road network, thus focusing on the environment. An entirely different perspective is used within multi-agent systems. In such settings, the environment of the agents remains static, while the interesting research questions concern the behavior of the agents themselves. The research focuses on the microscopic level and the resulting emergent behavior. This article puts such diverse meanings in the context of a research process that treats descriptive and prescriptive research as two sides of the same coin. We develop a framework to classify different types of simulation, based on the actual research activity they are intended to be used for. Two case studies supplement the framework

    Identification of Equid herpesvirus 2 in tissue-engineered equine tendon

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    Background: Incidental findings of virus-like particles were identified following electron microscopy of tissue-engineered tendon constructs (TETC) derived from equine tenocytes. We set out to determine the nature of these particles, as there are few studies which identify virus in tendons per se, and their presence could have implications for tissue-engineering using allogenic grafts. Methods: Virus particles were identified in electron microscopy of TETCs. Virion morphology was used to initially hypothesise the virus identity.  Next generation sequencing was implemented to identify the virus. A pan herpesvirus PCR was used to validate the RNASeq findings using an independent platform. Histological analysis and biochemical analysis was undertaken on the TETCs. Results: Morphological features suggested the virus to be either a retrovirus or herpesvirus. Subsequent next generation sequencing mapped reads to Equid herpesvirus 2 (EHV2). Histological examination and biochemical testing for collagen content revealed no significant differences between virally affected TETCs and non-affected TETCs. An independent set of equine superficial digital flexor tendon tissue (n=10) examined using designed primers for specific EHV2 contigs identified at sequencing were negative. These data suggest that EHV is resident in some equine tendon. Conclusions: EHV2 was demonstrated in equine tenocytes for the first time; likely from in vivo infection. The presence of EHV2 could have implications to both tissue-engineering and tendinopathy
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