164 research outputs found

    A Comprehensive Literature Review of American Sexual Assault Culture and the Status of Women\u27s Self-Defense

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    According to the National Organization for Women (NOW), 232,960 American women were raped or sexually assaulted in 2006, equating to more than 600 women daily (2012). American women furthermore experience about 4.8 million intimate partner-related physical assaults and rapes each year (NOW, 2012). Violence toward women is also evident on American college and university campuses. The U.S. National Institute of Justice (NIJ), for example, states that 35 of every 1,000 female students are victims of rape—either completed or attempted—in a given nine-month academic year (National Institute of Justice, 2005). With more than 600 women being raped daily, the pervasiveness of partner-related offenses, and the frequency of sexual violence occurring on American college campuses, the time is past due for American society to seriously confront, at all levels of discourse and implementation, the emotional, social, and spiritual devastation of sexual assault. This project aims to address American sexual assault and offers a potential solution. It is an extensive literature review regarding the prevalence of sexual assault, its different types, and its influential cultural factors in the United States. In addition, this review explores available preventative strategies and investigates, specifically, the current status of women’s self-defense programs en route to promoting women’s self-defense as a viable approach to minimizing America’s sexual assault culture

    Perinatal Air Pollutant Exposures and Autism Spectrum Disorder in the Children of Nurses’ Health Study II Participants

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    Objective: Air pollution contains many toxicants known to affect neurological function and to have effects on the fetus in utero. Recent studies have reported associations between perinatal exposure to air pollutants and autism spectrum disorder (ASD) in children. We tested the hypothesis that perinatal exposure to air pollutants is associated with ASD, focusing on pollutants associated with ASD in prior studies. Methods: We estimated associations between U.S. Environmental Protection Agency–modeled levels of hazardous air pollutants at the time and place of birth and ASD in the children of participants in the Nurses’ Health Study II (325 cases, 22,101 controls). Our analyses focused on pollutants associated with ASD in prior research. We accounted for possible confounding and ascertainment bias by adjusting for family-level socioeconomic status (maternal grandparents’ education) and census tract–level socioeconomic measures (e.g., tract median income and percent college educated), as well as maternal age at birth and year of birth. We also examined possible differences in the relationship between ASD and pollutant exposures by child’s sex. Results: Perinatal exposures to the highest versus lowest quintile of diesel, lead, manganese, mercury, methylene chloride, and an overall measure of metals were significantly associated with ASD, with odds ratios ranging from 1.5 (for overall metals measure) to 2.0 (for diesel and mercury). In addition, linear trends were positive and statistically significant for these exposures (p < .05 for each). For most pollutants, associations were stronger for boys (279 cases) than for girls (46 cases) and significantly different according to sex. Conclusions: Perinatal exposure to air pollutants may increase risk for ASD. Additionally, future studies should consider sex-specific biological pathways connecting perinatal exposure to pollutants with ASD

    Formation and Evolution of the Disk System of the Milky Way: [alpha/Fe] Ratios and Kinematics of the SEGUE G-Dwarf Sample

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    We employ measurements of the [alpha/Fe] ratio derived from low-resolution (R~2000) spectra of 17,277 G-type dwarfs from the SEGUE survey to separate them into likely thin- and thick-disk subsamples. Both subsamples exhibit strong gradients of orbital rotational velocity with metallicity, of opposite signs, -20 to -30 km/s/dex for the thin-disk and +40 to +50 km/s/dex for the thick-disk population. The rotational velocity is uncorrelated with Galactocentric distance for the thin-disk subsample, and exhibits a small trend for the thick-disk subsample. The rotational velocity decreases with distance from the plane for both disk components, with similar slopes (-9.0 {\pm} 1.0 km/s/kpc). Thick-disk stars exhibit a strong trend of orbital eccentricity with metallicity (about -0.2/dex), while the eccentricity does not change with metallicity for the thin-disk subsample. The eccentricity is almost independent of Galactocentric radius for the thin-disk population, while a marginal gradient of the eccentricity with radius exists for the thick-disk population. Both subsamples possess similar positive gradients of eccentricity with distance from the Galactic plane. The shapes of the eccentricity distributions for the thin- and thick-disk populations are independent of distance from the plane, and include no significant numbers of stars with eccentricity above 0.6. Among several contemporary models of disk evolution we consider, radial migration appears to have played an important role in the evolution of the thin-disk population, but possibly less so for the thick disk, relative to the gas-rich merger or disk heating scenarios. We emphasize that more physically realistic models and simulations need to be constructed in order to carry out the detailed quantitative comparisons that our new data enable.Comment: Accepted for publication in ApJ, 18 pages, 12 figures, 2 tables, emulateapj forma

    Justice in a Pandemic Briefing Two : Justice For All and The Economic Crisis

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    The world faces its most threatening economic crisis in almost 100 years. We are already experiencing mass job losses and bankruptcies as part of a sharp economic downturn, and a prolonged global depression is likely as at least 170 countries see their economies shrink. Previous financial crises and natural disasters triggered demand spikes and compounded existing problems in six key justice areas: crime, housing and land, family disputes, unemployment and bankruptcy, money and debt, and access to services. In a survey of 270 justice leaders from 20 countries, employment problems, debt, and bankruptcy were expected to account for the largest increases in justice problems as a result of the COVID-19 virus. It will be difficult for justice systems to meet the increased demand.12 Even before the pandemic, 1.5 billion people had justice problems they were unable to resolve.13 Now, with many formal and informal justice providers suspending services because of the health emergency and likely to face a surge in demand when they reopen, the burden on them will be unprecedented

    Justice in a Pandemic Briefing One : Justice for All and the Public Health Emergency

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    The COVID-19 pandemic is an unprecedented global emergency. It is not only a health crisis but also a human rights crisis. Justice actors face daunting responsibilities as they design, implement, and enforce new measures to prevent the spread of infection. Measures that heighten the risk of human rights abuses can undermine trust, at a time when the justice system most needs to maintain the public’s confidence. For better or for worse, justice systems and justice workers are on the frontline of this pandemic. If we get our response right, societies will be better able to confront the pandemic effectively and fairly. That will build the foundations for reset and recovery. If we get it wrong, it is no exaggeration to say that people will die unnecessarily. In the Justice for All report released last year, the Task Force on Justice noted that 1.5 billion people had a justice problem that they could not resolve. Now as well as before the pandemic, marginalized communities – already poorly served by justice systems – face the highest risks, as do vulnerable groups. The pandemic is widening the justice gap, with a sharp increase in the problems that many people face and the ability of justice actors to respond declining

    Chemical separation of disc components using RAVE

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    © 2016 The Authors. We present evidence from the RAdial Velocity Experiment (RAVE) survey of chemically separated, kinematically distinct disc components in the solar neighbourhood.We apply probabilistic chemical selection criteria to separate our sample into a-low ('thin disc') and a-high ('thick disc') sequences. Using newly derived distances,which will be utilized in the upcoming RAVE DR5, we explore the kinematic trends as a function of metallicity for each of the disc components. For our a-low disc, we find a negative trend in the mean rotational velocity (Vf) as a function of iron abundance ([Fe/H]). We measure a positive gradient ∂Vφ/∂[Fe/H] for the a-high disc, consistent with results from high-resolution surveys.We also find differences between the a-low and a-high discs in all three components of velocity dispersion.We discuss the implications of an a-low, metal-rich population originating from the inner Galaxy, where the orbits of these stars have been significantly altered by radial mixing mechanisms in order to bring them into the solar neighbourhood. The probabilistic separation we propose can be extended to other data sets for which the accuracy in [a/Fe] is not sufficient to disentangle the chemical disc components a priori. For such data sets which will also have significant overlap with Gaia DR1, we can therefore make full use of the improved parallax and proper motion data as it becomes available to investigate kinematic trends in these chemical disc components

    Revisiting the Relationship Between Fault Detection,Test Adequacy Criteria, and Test Set Size

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    The research community has long recognized a complex interrelationship between test set size, test adequacy criteria, and test effectiveness in terms of fault detection. However, there is substantial confusion about the role and importance of controlling for test set size when assessing and comparing test adequacy criteria. This paper makes the following contributions: (1) A review of contradictory analyses of the relationship between fault detection, test suite size, and test adequacy criteria. Specifically, this paper addresses the supposed contradiction of prior work and explains why test suite size is neither a confounding variable, as previously suggested,nor an independent variable that should be experimentally manipulated. (2) An explication and discussion of the experimental design and sampling strategies of prior work, together with a discussion of conceptual and statistical problems, and specific guidelines for future work. (3) A methodology for comparing test-adequacy criteria on an equal basis, which accounts for test suite size by treating it as a covariate. (4) An empirical evaluation that compares the effectiveness of coverage-based and mutation-based testing to one another and random testing. Additionally, this paper proposes probabilistic coupling, a methodology for approximating the representativeness of a set of test goals for a given set of real fault

    DNA Methylation Signatures of Chronic Low-Grade Inflammation Are Associated with Complex Diseases

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    Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade inflammation may reveal novel pathways or therapeutic targets for inflammation. Results: We performed a meta-analysis of epigenome-wide association studies (EWAS) of serum C-reactive protein (CRP), which is a sensitive marker of low-grade inflammation, in a large European population (n = 8863) and trans-ethnic replication in African Americans (n = 4111). We found differential methylation at 218 CpG sites to be associated with CRP (P \u3c 1.15 × 10–7) in the discovery panel of European ancestry and replicated (P \u3c 2.29 × 10–4) 58 CpG sites (45 unique loci) among African Americans. To further characterize the molecular and clinical relevance of the findings, we examined the association with gene expression, genetic sequence variants, and clinical outcomes. DNA methylation at nine (16%) CpG sites was associated with whole blood gene expression in cis (P \u3c 8.47 × 10–5), ten (17%) CpG sites were associated with a nearby genetic variant (P \u3c 2.50 × 10–3), and 51 (88%) were also associated with at least one related cardiometabolic entity (P \u3c 9.58 × 10–5). An additive weighted score of replicated CpG sites accounted for up to 6% inter-individual variation (R2) of age-adjusted and sex-adjusted CRP, independent of known CRP-related genetic variants. Conclusion: We have completed an EWAS of chronic low-grade inflammation and identified many novel genetic loci underlying inflammation that may serve as targets for the development of novel therapeutic interventions for inflammation

    Herbivore metabolism and stoichiometry each constrain herbivory at different organizational scales across ecosystems

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    Plant-herbivore interactions mediate the trophic structure of ecosystems. We use a comprehensive data set extracted from the literature to test the relative explanatory power of two contrasting bodies of ecological theory, the metabolic theory of ecology (MTE) and ecological stoichiometry (ES), for per-capita and population-level rates of herbivory across ecosystems. We found that ambient temperature and herbivore body size (MTE) as well as stoichiometric mismatch (ES) both constrained herbivory, but at different scales of biological organization. Herbivore body size, which varied over 11 orders of magnitude, was the primary factor explaining variation in per-capita rates of herbivory. Stoichiometric mismatch explained more variation in population-level herbivory rates and also in per-capita rates when we examined data from within functionally similar trophic groups (e.g. zooplankton). Thus, predictions from metabolic and stoichiometric theories offer complementary explanations for patterns of herbivory that operate at different scales of biological organization
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