Cutaneous sarcoidosis: A rare case report

Sarcoidosis is a Greek word (Sarco means flesh and Eido means type or like). Cutaneous sarcoidosis occurs in up to one third of patients with systemic sarcoidosis. This disease is characterised by the presence of non – caseating epitheloid cell granulomas in the skin. Cutaneous sarcoidosis presents as a diagnostic challenge to the dermatopathologists due to its varied presentations and almost identical histologic pictures. Hence, exclusion of infectious causes and compatibility with clinical and radiologic picture serve as significant criteria to come up to a diagnosis. Sometimes; skin lesions are the first manifestation of systemic sarcoidosis. This is not a contagious or allergic disease. There is a risk of development of systemic manifestations at a later date; for which a close follow up is a must. We are presenting a case of cutaneous sarcoidosis, which later on progress to sarcoidosis with systemic manifestations.\ud \u

(SI10-062) Comprehensive Study on Methodology of Orthogonal Interleavers

Interleaving permutes the data bits by employing a user defined sequence to reduce burst error which at times exceeds the minimum hamming distance. It serves as the sole medium to distinguish user data in the overlapping channel and is the heart of Interleave Division Multiple Access (IDMA) scheme. Versatility of interleavers relies on various design parameters such as orthogonality, correlation, latency and performance parameters like bit error rate (BER), memory occupancy and computation complexity. In this paper, a comprehensive study of interleaving phenomenon and discussion on numerous interleavers is presented. Also, the BER performance of interleavers using IDMA scheme is displayed

Ultra-Stretchable Interconnects for High-Density Stretchable Electronics

The exciting field of stretchable electronics (SE) promises numerous novel applications, particularly in-body and medical diagnostics devices. However, future advanced SE miniature devices will require high-density, extremely stretchable interconnects with micron-scale footprints, which calls for proven standardized (complementary metal-oxide semiconductor (CMOS)-type) process recipes using bulk integrated circuit (IC) microfabrication tools and fine-pitch photolithography patterning. Here, we address this combined challenge of microfabrication with extreme stretchability for high-density SE devices by introducing CMOS-enabled, free-standing, miniaturized interconnect structures that fully exploit their 3D kinematic freedom through an interplay of buckling, torsion, and bending to maximize stretchability. Integration with standard CMOS-type batch processing is assured by utilizing the Flex-to-Rigid (F2R) post-processing technology to make the back-end-of-line interconnect structures free-standing, thus enabling the routine microfabrication of highly-stretchable interconnects. The performance and reproducibility of these free-standing structures is promising: an elastic stretch beyond 2000% and ultimate (plastic) stretch beyond 3000%, with 10 million cycles at 1000% stretch with <1% resistance change. This generic technology provides a new route to exciting highly-stretchable miniature devices.Comment: 13 pages, 5 figure, journal publicatio

Essential oil composition and antimicrobial activity of Lobelia pyramidalis Wall

The essential oil of Lobelia pyramidalis was analyzed by GC and GC-MS. A total of 21 con-stituents comprising 77.88 % of the total oil were identified. Perilla ketone constituted 25.61 % of the oil followed by camphorquinone (12.16 %), dibutyl phthalate (10.66 %) and allyl nonanoate (8.47 %). The antimicrobial activity of the oil was evaluated using the disc diffusion method and the microdilution technique. The results showed that the oil exhibited moderate antimicrobial activity

Sustainable Construction by Provisions of Bio-Sanitation

Stepping into the 21st century, coupled with enormous scientific development we also face a grave threat of resource depletion and pollution leading to poor health conditions. The most significant contribution of this pollution comes from various construction activities. From pre-construction to post-construction activities, huge amount of resources are spent on erecting as well as maintaining a building. Even with all leading innovations concerning sustainable construction, we have left out the extensive role of sanitation that could prove to be a pivotal path towards obtaining sustainable buildings. Thus, this paper aims at the innovative use of Bio-toilets in collaboration with Bio-Gas to unveil their use and adaption to not only traditional buildings, but even high rise structures

Quantitative measures of personal response device effectiveness

Presented at the 232nd National Meeting of the American Chemical Society. San Francisco, CA.The use of personal response devices (or “clickers”) in the classroom is becoming more frequent. Quantitative results have been used to assess clicker effectiveness in both general and physical chemistry. Changes in classroom engagement were investigated in the general chemistry classes. In one term, the clicker use was optional, while in the other term, clicker use was tied to a participation grade. In all classes, exam grades for students who consistently used clickers were higher than those for students who didn’t. Information retention was tested with a comparison of student performance on clicker questions and related exam questions. In some cases, a clicker question was used as an exam question. In most cases, student performance improved on the exams relative to the in-class performance (as recorded with clickers)

Survey on Ayurvedic formulations used for treatment of various diseases

Ayur' means 'Life' and 'Veda' means 'Science'. Thus Ayurveda is the 'Science of Life'. Ayurveda helps the healthy person to maintain health and the diseased person to regain health. Also currently various scientists are moving towards Ayurveda to find out the treatment of various diseases and also due to various side effects concerned with allopathic system of medication.The current aim of our project work was to perform a survey on the ayurvedic formulations used for treatment of various diseases like Fever, Arthritis, Alopecia and Nephrolithiasis. For the purpose of the study a questionnaire was prepared and survey was performed on various selected areas in which various Ayurveda practitioners were asked about various formulations for the treatment of these diseases. The responses obtained from the doctors were arranged in the tabular format and arranged graphically to find out various inferences.As the result of the survey it was found that most of the people Ayurvedic medicines as almost all ayurvedic medicine has no any side effect and no drug dependence and drug tolerance which is very common in allopathic medicine. Also ayurvedic medication system is traditional and has a good history of recovery from the ancient time.Â

Central Composite Designed Formulation, Characterization and In-Vitro Cytotoxic effect of Erlotinib Loaded Chitosan Nanoparticulate System

© 2019 Elsevier B.V. The most common cause of deaths due to cancers nowadays is lung cancer. The objective of this study was to prepare erlotinib loaded chitosan nanoparticles for their anticancer potential. To study the effect of formulation variables on prepared nanoparticles using central composite design. Erlotinib loaded chitosan nanoparticles were prepared by ionic gelation method using probe sonication technique. It was found that batch NP-7 has a maximum loading capacity and entrapment efficiency with a particle size (138.5 nm) which is ideal for targeting solid tumors. Analysis of variance was applied to the particle size, entrapment efficiency and percent cumulative drug release to study the fitting and the significance of the model. The batch NP-7 showed 91.57% and 39.78% drug release after 24 h in 0.1 N hydrochloric acid and Phosphate Buffer (PB) pH 6.8, respectively. The IC50 value of NP-7 evaluated on A549 Lung cancer cells was found to be 6.36 μM. The XRD of NP-7 displayed the existence of erlotinib in the amorphous pattern. The optimized batch released erlotinib slowly in comparison to the marketed tablet formulation. Erlotinib loaded chitosan nanoparticles were prepared successfully using sonication technique with suitable particle size, entrapment efficiency and drug release. The formulated nanoparticles can be utilized for the treatment of lung cancer

Seasonal analysis of submicron aerosol in Old Delhi using high-resolution aerosol mass spectrometry: chemical characterisation, source apportionment and new marker identification

We present the first real-time composition of submicron particulate matter (PM1) in Old Delhi using high-resolution aerosol mass spectrometry (HR-AMS). Old Delhi is one of the most polluted locations in the world, and PM1 concentrations reached ∼ 750 µg m−3 during the most polluted period, the post-monsoon period, where PM1 increased by 188 % over the pre-monsoon period. Sulfate contributes the largest inorganic PM1 mass fraction during the pre-monsoon (24 %) and monsoon (24 %) periods, with nitrate contributing most during the post-monsoon period (8 %). The organics dominate the mass fraction (54 %–68 %) throughout the three periods, and, using positive matrix factorisation (PMF) to perform source apportionment analysis of organic mass, two burning-related factors were found to contribute the most (35 %) to the post-monsoon increase. The first PMF factor, semi-volatility biomass burning organic aerosol (SVBBOA), shows a high correlation with Earth observation fire counts in surrounding states, which links its origin to crop residue burning. The second is a solid fuel OA (SFOA) factor with links to local open burning due to its high composition of polyaromatic hydrocarbons (PAHs) and novel AMS-measured marker species for polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). Two traffic factors were resolved: one hydrocarbon-like OA (HOA) factor and another nitrogen-rich HOA (NHOA) factor. The N compounds within NHOA were mainly nitrile species which have not previously been identified within AMS measurements. Their PAH composition suggests that NHOA is linked to diesel and HOA to compressed natural gas and petrol. These factors combined make the largest relative contribution to primary PM1 mass during the pre-monsoon and monsoon periods while contributing the second highest in the post-monsoon period. A cooking OA (COA) factor shows strong links to the secondary factor, semi-volatility oxygenated OA (SVOOA). Correlations with co-located volatile organic compound (VOC) measurements and AMS-measured organic nitrogen oxides (OrgNO) suggest SVOOA is formed from aged COA. It is also found that a significant increase in chloride concentrations (522 %) from pre-monsoon to post-monsoon correlates well with SVBBOA and SFOA, suggesting that crop residue burning and open waste burning are responsible. A reduction in traffic emissions would effectively reduce concentrations across most of the year. In order to reduce the post-monsoon peak, sources such as funeral pyres, solid waste burning and crop residue burning should be considered when developing new air quality policy