Cooperative Adaptive Cruise Control: Critical Human Factors Issues and Research Questions

As traffic volume and delay on highways increase each year, new solutions are required to meet travel demand and ease congestion. One possible solution, Cooperative Adaptive Cruise Control, permits vehicles and infrastructure to communicate, providing the capability to maintain safety while increasing travel lane capacity. The technical capabilities have been demonstrated, but as important to ensuring successful implementation is an understanding of the potential human factors-related issues. Use of automation in the driving environment can have numerous pitfalls, which are heavily influenced by a variety of both deliberate and reflexive human judgments and decisions known to be error-prone. This paper examines these potential issues and identifies research areas and questions that may guide future research to evaluate the safety, efficacy, and acceptance of this new technology

Bacterial community profiles and Vibrio parahaemolyticus abundance in individual oysters and their association with estuarine ecology

Oysters naturally harbor the human gastric pathogen Vibrio parahaemolyticus, but the nature of this association is unknown. Because microbial interactions could influence the accumulation of V. parahaemolyticus in oysters, we investigated the composition of the microbiome in water and oysters at two ecologically unique sites in the Great Bay Estuary, New Hampshire using 16s rRNA profiling. We then evaluated correlations between bacteria inhabiting the oyster with V. parahaemolyticus abundance quantified using a most probable number (MPN) analysis. Even though oysters filter-feed, their microbiomes were not a direct snapshot of the bacterial community in overlaying water, suggesting they selectively accumulate some bacterial phyla. The microbiome of individual oysters harvested more centrally in the bay were relatively more similar to each other and had fewer unique phylotypes, but overall more taxonomic and metabolic diversity, than the microbiomes from tributary-harvested oysters that were individually more variable with lower taxonomic and metabolic diversity. Oysters harvested from the same location varied in V. parahaemolyticus abundance, with the highest abundance oysters collected from one location. This study, which to our knowledge is the first of its kind to evaluate associations of V. parahaemolyticus abundance with members of individual oyster microbiomes, implies that sufficient sampling and depth of sequencing may reveal microbiome members that could impact V. parahaemolyticus abundance

Evolution of Medical Students\u27 Understanding of Systems-Based Practice: A Qualitative Account

Reflective writing is a useful tool in medical education to analyze student experiences and measure development of certain skills. This tool is particularly useful in identifying skill components of systems-based practice. These skills are necessary for any practicing physician, but are of particular importance as they are a required residency competency. There is now additional focus on systems-based practice with the passage of the Patient Protection and Affordable Care Act (ACA). In this qualitative, grounded theory study, the reflective writings of students at a United States medical school were analyzed using the constant comparative method to explore how the focus of a medical student progresses through the clinical curriculum. The interprofessional team of researchers specifically sought to determine if areas of medical student focus evolve vertically across the curriculum and if in the process students develop an understanding of systems-based practice. The data supported both of these objectives, and actively supports future research to identify ways, both inside and outside the curriculum, to leverage the students’ natural progression of focus in order to expand systems-based practice education

Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep-wake phase disorder in a sleep clinic population.

Study objectivesReport the first prevalence estimates of advanced sleep phase (ASP), familial advanced sleep phase (FASP), and advanced sleep-wake phase disorder (ASWPD). This can guide clinicians on the utility of screening for extreme chronotypes both for clinical decision-making and to flag prospective participants in the study of the genetics and biology of FASP.MethodsData on morning or evening sleep schedule preference (chronotype) were collected from 2422 new patients presenting to a North American sleep center over 9.8 years. FASP was determined using a severity criterion that has previously identified dominant circadian mutations in humans. All patients were personally seen and evaluated by one of the authors (C.R.J.).ResultsOur results demonstrate an ASP prevalence of 0.33%, an FASP prevalence of 0.21%, and an ASWPD prevalence of at least 0.04%. Most cases of young-onset ASP were familial.ConclusionsAmong patients presenting to a sleep clinic, conservatively 1 out of every 300 patients will have ASP, 1 out of every 475 will have FASP, and 1 out of every 2500 will have ASWPD. This supports obtaining a routine circadian history and, for those with extreme chronotypes, obtaining a family history of circadian preference. This can optimize treatment for evening sleepiness and early morning awakening and lead to additional circadian gene discovery. We hope these findings will lead to improved treatment options for a wide range of sleep and medical disorders in the future

A 15-Kiloparsec X-Ray Disk in the Elliptical Galaxy NGC 1700

We present Chandra observations of the young elliptical galaxy NGC 1700. The X-ray isophotes are highly flattened between semimajor axes of 30 and 80 arcseconds, reaching a maximum ellipticity of approximately 0.65 at 60 arcsec (15 kpc). The surface brightness profile in the spectrally soft, flattened region is shallower than that of the starlight, indicating that the emission comes from hot gas rather than stellar sources. The flattening is so extreme that the gas cannot be in hydrostatic equilibrium in any plausible potential. A likely alternative is that the gas has significant rotational support. A simple model, representing isothermal gas distributed about a particular angular momentum, can reproduce the X-ray morphology while staying consistent with stellar kinematics. The specific angular momentum of the gas matches that of the stars in the most isophotally distorted outer part of the galaxy, and its cooling time matches the time since the last major merger. We infer that the gas was acquired in that merger, which involved a pre-existing elliptical galaxy with a hot ISM. The hot gas carried the angular momentum of the encounter, and has since gradually settled into a rotationally flattened, cooling disk.Comment: 11 pages, 2 figures, AASTeX 5.0. Accepted for publication in The Astrophysical Journa

The Genetic Component of the Forced Diving Bradycardia Response in Mammals

We contrasted the forced diving bradycardia between two genetically similar (inbred) rat strains (Fischer and Buffalo), compared to that of outbred rats (Wistar). The animals were habituated to forced diving for 4 weeks. Each animal was then tested during one 40 s dive on each of 3 days. The heart rate (fH) was measured before, during, and after each dive. Fischer and Buffalo exhibited marked difference in dive bradycardia (Fischer: 120.9 ± 14.0 beats min−1 vs. Buffalo: 92.8 ± 12.8 beats min−1, P < 0.05). Outbred rats showed an intermediate response (103.0 ± 30.9 beats min−1) but their between-animal variability in mean dive fH and pre-diving resting fH were higher than the inbred strains (P < 0.05), which showed no difference (P > 0.05). The decreased variability in fH in inbred rats as compared with the outbred group indicates that reduced genetic variability minimizes variability of the diving bradycardia between individuals. Heritability within strains was assessed by the repeatability (R) index and was 0.93 ± 0.05 for the outbred, 0.84 ± 0.16 for Buffalo, and 0.80 ± 0.12 for Fischer rats for fH during diving. Our results suggest that a portion of the mammalian diving bradycardia may be a heritable trait

Report on Recent Upgrades to the Curved Duct Test Rig at NASA Langley Research Center

The Curved Duct Test Rig (CDTR) is an experimental facility that is designed to assess the acoustic and aerodynamic performance of aircraft engine nacelle liners in close to full scale. The test section is between 25% and 100% of the scale of aft bypass ducts of aircraft engines ranging in size from business jet to large commercial passenger jet. The CDTR has been relocated and now shares space with the Grazing Flow Impedance Tube in the Liner Technology Facility at NASA Langley Research Center. As a result of the relocation, research air is supplied to the CDTR from a 50,000 cfm centrifugal fan. This new air supply enables testing of acoustic liner samples at up to Mach 0.500. This paper documents experiments and analysis on a baseline liner sample, which the authors had analyzed and reported on prior to the move to the new facility. In the present paper, the experimental results are compared to those obtained previously in order to ensure continuity of the experimental capability. Experiments that take advantage of the facility s expanded capabilities are also reported. Data analysis features that enhance understanding of the physical properties of liner performance are introduced. The liner attenuation is shown to depend on the mode that is incident on the liner test section. The relevant parameter is the mode cut-on ratio, which determines the angle at which the sound wave is incident on the liner surface. The scattering of energy from the incident mode into higher order, less attenuated modes is demonstrated. The configuration of the acoustic treatment, in this case lined on one surface and hard wall on the opposite surface, is shown to affect the mode energy redistribution

Configuration Effects on Liner Performance

The acoustic performance of a duct liner depends not only on the intrinsic properties of the liner but also on the configuration of the duct in which it is used. A series of experiments is performed in the NASA Langley Research Center Curved Duct Test Rig (at Mach 0.275) to evaluate the effect of duct configuration on the acoustic performance of single degree of freedom perforate-over-honeycomb liners. The liners form the sidewalls of the duct's test section. Variations of duct configuration include: asymmetric (liner on one side and hard wall opposite) and symmetric (liner on both sides) wall treatment; inlet and exhaust orientation, in which the sound propagates either against or with the flow; and straight and curved flow path. The effect that duct configuration has on the overall acoustic performance, particularly the shift in frequency and magnitude of peak attenuation, is quantified. The redistribution of incident mode content is shown. The liners constitute the side walls of the liner test section and the scatter of incident horizontal order 1 mode by the asymmetric treatment and order 2 mode by the symmetric treatment into order 0 mode is shown. Scatter of order 0 incident modes into higher order modes is also shown. This redistribution of mode content is significant because it indicates that the liner design can be manipulated such that energy is scattered into more highly attenuated modes, thus enhancing liner performance