158 research outputs found

    Nelinearno upravljanje s unutarnjim modelom za pogon s prekidačkim reluktantnim motorom bez oscilacija momenta

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    Based on the nonlinear internal-model control (IMC), associated with the suitable commutation strategy, a novel control solution for switched reluctance motor (SRM) is formulated and designed. The commutation strategy uses a definite critical rotor position as commutation point, which reduces the computational burden. The nonlinear IMC-based voltage control scheme for SRM extracts the simplicity of the feedback linearization control and the robustness of IMC structure, which ensures the torque ripple-free and the drive\u27s robustness in spite of the plant-model mismatch disturbances. Some important properties are presented. Simulation results show that the high-performance control for SRM has been achieved.Predloženo je i razrađeno novo rješenje za upravljanje sklopnim reluktantnim motorom (SRM) zasnovano na nelinearnom upravljanju s unutarnjim modelom (IMC) i prikladnoj strategiji komutacije. Strategija komutacije koristi definiranu kritičnu poziciju rotora kao točku komutacije što doprinosi smanjenju računskih zahtjevnosti. Shema za upravljanje naponom SRM-a zasnovana na nelinearnom IMC-u osigurava linearizaciju zatvorenog sustava i robusnost IMC strukture što rezultira ukupnom robusnošću pogona bez oscilacija momenta unatoč nepodudaranju modela smetnji sa stvarnim smetnjama. Opisana su neka važna svojstva ovoga načina upravljanja. Simulacijskim se rezultatima pokazuje visoka kvaliteta upravljanja SRM-a

    An effective diagnosis method for single and multiple defects detection in gearbox based on nonlinear feature selection and kernel-based extreme learning machine

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    Gear transmissions have been widely used in most of today’s manufacturing and production industries; however, they often suffer from deteriorations and damages on gear pairs. Severe damages of the machinery caused by the failures of gears account for 48 %, leading to significant economic losses. Therefore it is crucial to implement fault diagnosis procedure for gearboxes. The gear meshing motion is a kind of typical strong nonlinear movement, and the related vibration signals are the nonlinear mixtures of different kinds of vibration source, leading to great difficulty in the fault feature extraction and fault detection. In order to improve the fault detection of gearboxes, a new method based on the nonlinear fault feature selection and intelligent fault identification is proposed in this work. The blind source separation (BSS) procedure was firstly employed to eliminate the influence of noise signal sources. The useful information related to the fault vibration was hence separated by the independent component analysis (ICA). Then the spectral regression (SR) was used as a nonlinear feature selection technique for the separated vibration sources. Hence, distinct fault features can be obtained. Lastly, the kernel-based extreme learning machine (KELM) was applied for the pattern recognition of single and multiply faults of the gearbox. The fault vibration data acquired from a gearbox fault experimental tester was used to valuate the proposed diagnostic method. The experiment results show that useful fault vibration signals can be separated by the new method, and the fault detection rate of the proposed method is superior to the existing approaches with an increase of 4.4 % or better. Hence, this new development will produce considerable savings by reducing unplanned outages of machinery so a company can get the full benefit from condition monitoring

    A Petunia homeodomain-leucine zipper protein, PhHD-Zip, plays an important role in flower senescence.

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    Flower senescence is initiated by developmental and environmental signals, and regulated by gene transcription. A homeodomain-leucine zipper transcription factor, PhHD-Zip, is up-regulated during petunia flower senescence. Virus-induced gene silencing of PhHD-Zip extended flower life by 20% both in unpollinated and pollinated flowers. Silencing PhHD-Zip also dramatically reduced ethylene production and the abundance of transcripts of genes involved in ethylene (ACS, ACO), and ABA (NCED) biosynthesis. Abundance of transcripts of senescence-related genes (SAG12, SAG29) was also dramatically reduced in the silenced flowers. Over-expression of PhHD-Zip accelerated petunia flower senescence. Furthermore, PhHD-Zip transcript abundance in petunia flowers was increased by application of hormones (ethylene, ABA) and abiotic stresses (dehydration, NaCl and cold). Our results suggest that PhHD-Zip plays an important role in regulating petunia flower senescence

    The nuclear factor-κB inhibitor pyrrolidine dithiocarbamate reduces polyinosinic-polycytidilic acid-induced immune response in pregnant rats and the behavioral defects of their adult offspring

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    <p>Abstract</p> <p>Background</p> <p>Epidemiological studies have indicated that maternal infection during pregnancy may lead to a higher incidence of schizophrenia in the offspring. It is assumed that the maternal infection increases the immune response, leading to neurodevelopmental disorders in the offspring. Maternal polyinosinic-polycytidilic acid (PolyI:C) treatment induces a wide range of characteristics in the offspring mimicking some schizophrenia symptoms in humans. These observations are consistent with the neurodevelopmental hypothesis of schizophrenia.</p> <p>Methods</p> <p>We examined whether suppression of the maternal immune response could prevent neurodevelopmental disorders in adult offspring. PolyI:C or saline was administered to early pregnant rats to mimic maternal infection, and the maternal immune response represented by tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) levels was determined by enzyme-linked immunosorbent assays (ELISA). The NF-κB inhibitor pyrrolidine dithiocarbamate (PDTC) was used to suppress the maternal immune response. Neurodevelopmental disorders in adult offspring were examined by prepulse inhibition (PPI), passive avoidance, and active avoidance tests.</p> <p>Results</p> <p>PolyI:C administration to early pregnant rats led to elevated serum cytokine levels as shown by massive increases in serum TNF-α and IL-10 levels. The adult offspring showed defects in prepulse inhibition, and passive avoidance and active avoidance tests. PDTC intervention in early pregnant rats suppressed cytokine increases and reduced the severity of neurodevelopmental defects in adult offspring.</p> <p>Conclusions</p> <p>Our findings suggest that PDTC can suppress the maternal immune response induced by PolyI:C and partially prevent neurodevelopmental disorders of adult offspring.</p

    Comparison of lignocellulose composition in four major species of Miscanthus

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    Miscanthus is a perennial grass rich in lignocellulose that has attracted interest as a non-food crop for renewable bioenergy with major environmental and economic benefits for China. The lignocellulose composition of whole stems of four major species of Miscanthus was assessed. The average values of total moisture content (TMC) (61.90%) and hemicelluloses (34.86%) were the highest while cellulose (32.71%) and acid detergent lignin (ADL) (8.90%) were the lowest in Miscanthus floridulus. On the contrary, the contents of cellulose (42.11%) and ADL (13.64%) were the highest and total ash (TA) (2.89%) was the lowest in Miscanthus lutarioriparius. The Shannon–Weaver diversity indices of components for the four species showed that hemicellulose content (H’= 2.00±0.11) was the most variable trait followed by cellulose (H’= 1.84±0.07), then ADL (H’= 1.84±0.07). The variational range of each component was relatively higher in Miscanthus sacchariflorus. In M. lutarioriparius, the diversity indices of each component were moderate. The diversity of cellulose was the highest and hemicellulose, ADL, TA and TMC were low in Miscanthus sinensis. By correlation analysis, neutral detergent fiber (NDF) significantly and positively correlated with ADF, cellulose and ADL at P&lt;0.01 as well as the relationship of cellulose and ADL in the four species. Hemicellulose showed significant (P&lt;0.01) but negative correlation with cellulose and ADL in M. floridulus, M. lutarioriparius and M. sacchariflorus. By principal component analysis (PCA), the components ADF and cellulose were the PC1 that were considered the foremost for the evaluation and selection of resource in the four species. The conclusions show that lignocellulose composition contents of Miscanthus culms were different. M. floridulus was more fit to ethanol fermentation. Though the components contents in M. sinensis and M. sacchariflorus were moderate, the range of choice was large. It provided a possible means to screen the appropriate materials according to different utilization. M. lutarioriparius had more superiorities relatively. So the four species of Miscanthus were appropriate for extension as excellent herbaceous energy plants, though, reasonable species choice should be employed according to the conversion approach and the growth characteristics, productivity levels and biomass quality characteristics of these tall grasses.Keywords: Miscanthus, bioenergy, lignocellulose compositions, detergent fiber, diversity analysis, PC

    Interictal Abnormalities of Neuromagnetic Gamma Oscillations in Migraine Following Negative Emotional Stimulation

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    Here, we aimed to investigate brain activity in migraineurs in response to emotional stimulation. Magnetoencephalography (MEG) was used to examine 20 patients with episodic migraine (EM group), 15 patients with chronic migraine (CM group), and 35 healthy participants (control group). Neuromagnetic brain activity was elicited by emotional stimulation using photographs of facial expressions. We analyzed the latency and amplitude of M100 and M170 components and used Morlet wavelet and beamformers to analyze the spectral and spatial signatures of MEG signals in gamma band (30–100 Hz). We found that the timing and frequency of MEG activity differed across the three groups in response negative emotional stimuli. First, peak M170 amplitude was significantly lower in the CM group than in the control group. Second, compared with the control group, the average spectral power was significantly lower in the EM group and CM group at M100 and M170. Third, the average spectral powers of the M100 and M170 in the CM group were negatively correlated with either HAM-D scores or migraine attack frequency. No significant differences across groups was found for positive or neutral emotional stimuli. Furthermore, after negative emotional stimuli, the MEG source analysis demonstrated that the CM group showed a significantly higher percentage of amygdala activation than the control group for M100 and M170. Thus, during headache free phases, migraineurs have abnormal brain activity in the gamma band in response to negative emotional stimuli.Trial Registration:ChiCTR-RNC-17012599. Registered 7 September, 2017

    Effects of oral intake fruit or fruit extract on skin aging in healthy adults: a systematic review and Meta-analysis of randomized controlled trials

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    BackgroundIn recent years, oral various fruits or supplements of fruits natural extracts have been reported to have significant anti-aging effects on the skin (1, 2), However, despite many studies on this topic, there is often no clear evidence to support their efficacy and safety. In this paper, we present a comprehensive review and Meta-analysis of the evidence for the safety and efficacy of oral fruits and fruits extracts in improving skin aging.MethodsFour databases, Pubmed, Embase, Web of Science, and Cochrane Library (CENTRAL), were searched for relevant literature from 2000–01 to 2023–03. Seven randomized controlled trials (RCTs) of fruit intake or fruit extracts associated with anti-skin aging were screened for Meta-analysis.ResultsCompared to placebo, oral intake of fruit or fruit extracts showed significant statistical differences in skin hydration and transepidermal water loss (TEWL), with a significant improvement in skin hydration and a significant decrease in TEWL. No significant statistical difference was observed in minimal erythema dose (MED), overall skin elasticity (R2), or wrinkle depth, and no evidence of significant improvement in skin condition was observed.ConclusionMeta-analysis results suggest that consume administration of fruits or fruit extracts significantly enhances skin hydration and reduces transcutaneous water loss, but there is insufficient evidence to support other outcome recommendations, including minimal erythema dose (MED), overall skin elasticity(R2), and wrinkle depth. Systematic Review Registration PROSPERO (york.ac.uk), identifier CRD42023410382
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