Why Are Ring Galaxies Interesting?

Compared with ordinary spirals, the ISM in ring galaxies experiences markedly different physical conditions and evolution. As a result, ring galaxies provide interesting perspectives on the triggering/quenching of large scale star formation and the destructive effects of massive stars on molecular cloud complexes. We use high resolution radio, sub-millimeter, infrared, and optical data to investigate the role of gravitational stability in star formation regulation, factors influencing the ISM's molecular fraction, and evidence of peculiar star formation laws and efficiencies in two highly evolved ring galaxies: Cartwheel and the Lindsay-Shapley ring.Comment: 6 pages with 4 figures (2 color). To appear in the conference proceedings for "Galaxy Wars: Stellar Populations and Star Formation in Interacting Galaxies"

Feminist Geopolitics: Material States

No abstract available

Determinants and outcomes of motivation in health professions education: a systematic review based on self-determination theory

Purpose: This study aimed at conducting a systematic review in health professions education of determinants, mediators and outcomes of students’ motivation to engage in academic activities based on the self-determination theory’s perspective. Methods: A search was conducted across databases (MEDLINE, CINHAL, EMBASE, PsycINFO, and ERIC databases), hand-search of relevant journals, grey literature, and published research profile of key authors. Quantitative and qualitative studies were included if they reported research in health professions education focused on determinants, mediators, and/or outcomes of motivation from the self-determination and if meeting the quality criteria. Results: A total of 17 studies met the inclusion and quality criteria. Articles retrieved came from diverse locations and mainly from medical education and to a lesser extent from psychology and dental education. Intrapersonal (gender and personality traits) and interpersonal determinants (academic conditions and lifestyle, qualitative method of selection, feedback, and an autonomy supportive learning climate) have been reported to have a positive influence on students’ motivation to engage in academic activities. No studies were found that tested mediation effects between determinants and students’ motivation. In turn, students’ self-determined motivation has been found to be positively associated with different cognitive, affective, and behavioural outcomes. Conclusion: This study has found that generally, motivation could be enhanced by changes in the educational environment and by an early detection of students’ characteristics. Doing so may support future health practitioners’ self-determined motivation and positively influence how they process information and their emotions and how they approach their learning activities

Isolation, characterisation and experimental evolution of phage that infect the horse chestnut tree pathogen, Pseudomonas syringae pv. aesculi

Bleeding canker of horse chestnut trees is a bacterial disease, caused by the bacterium Pseudomonas syringae pv. aesculi, estimated to be present in ~ 50% of UK horse chestnut trees. Currently, the disease has no cure and tree removal can be a common method of reducing inoculum and preventing spread. One potential method of control could be achieved using naturally occurring bacteriophages infective to the causative bacterium. Bacteriophages were isolated from symptomatic and asymptomatic horse chestnut trees in three locations in the South East of England. The phages were found to be belonging to both the Myoviridae and Podoviridae families by RAPD PCR and transmission electron microscopy. Experimental coevolution was carried out to understand the dynamics of bacterial resistance and phage infection and to determine whether new infective phage genotypes would emerge. The phages exhibited different coevolution patterns with their bacterial hosts across time. This approach could be used to generate novel phages for use in biocontrol cocktails in an effort to reduce the potential emergence of bacterial resistance

Molecular Gas and Star Formation in the Cartwheel

Atacama Large Millimeter/submillimeter Array (ALMA) 12CO(J=1-0) observations are used to study the cold molecular ISM of the Cartwheel ring galaxy and its relation to HI and massive star formation (SF). CO moment maps find $(2.69\pm0.05)\times10^{9}$ M$_{\odot}$ of H$_2$ associated with the inner ring (72%) and nucleus (28%) for a Galactic I(CO)-to-N(H2) conversion factor ($\alpha_{\rm CO}$). The spokes and disk are not detected. Analysis of the inner ring's CO kinematics show it to be expanding ($V_{\rm exp}=68.9\pm4.9$ km s$^{-1}$) implying an $\approx70$ Myr age. Stack averaging reveals CO emission in the starburst outer ring for the first time, but only where HI surface density ($\Sigma_{\rm HI}$) is high, representing $M_{\rm H_2}=(7.5\pm0.8)\times10^{8}$ M$_{\odot}$ for a metallicity appropriate $\alpha_{\rm CO}$, giving small $\Sigma_{\rm H_2}$ ($3.7$ M$_{\odot}$ pc$^{-2}$), molecular fraction ($f_{\rm mol}=0.10$), and H$_2$ depletion timescales ($\tau_{\rm mol} \approx50-600$ Myr). Elsewhere in the outer ring $\Sigma_{\rm H_2}\lesssim 2$ M$_{\odot}$ pc$^{-2}$, $f_{\rm mol}\lesssim 0.1$ and $\tau_{\rm mol}\lesssim 140-540$ Myr (all $3\sigma$). The inner ring and nucleus are H$_2$-dominated and are consistent with local spiral SF laws. $\Sigma_{\rm SFR}$ in the outer ring appears independent of $\Sigma_{\rm H_2}$, $\Sigma_{\rm HI}$ or $\Sigma_{\rm HI+H_2}$. The ISM's long confinement in the robustly star forming rings of the Cartwheel and AM0644-741 may result in either a large diffuse H$_2$ component or an abundance of CO-faint low column density molecular clouds. The H$_2$ content of evolved starburst rings may therefore be substantially larger. Due to its lower $\Sigma_{\rm SFR}$ and age the Cartwheel's inner ring has yet to reach this state. Alternately, the outer ring may trigger efficient SF in an HI-dominated ISM.Comment: 10-pages text; 5-figure

Spitzer Observations of Tidal Dwarf Galaxies

We present Spitzer observations of Tidal Dwarf Galaxies (TDGs) in three interacting systems: NGC 5291, Arp 105 & Stephan’s Quintet. The spectra show bright emission from polyaromatic hydrocarbons (PAHs), nebular lines and warm molecular hydrogen, characteristic of recent episodes of star formation. The PAH emission that falls in the IRAC 8.0 µm band leads to the TDGs having an extremely red IRAC color, with [4.5] − [8.0] \u3e 3. The emission from PAHs is characterized by a model with mainly neutral 100-C PAH atoms

Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi.

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% to 40% after 1 and 3 months of a high-fructose diet (both P < 0.001 vs. baseline). During fructose-induced metabolic dysregulation, plasma ANGPTL3 concentrations were positively correlated with circulating indices of insulin resistance [assessed with fasting insulin and the homeostatic model assessment of insulin resistance (HOMA-IR)], hypertriglyceridemia, adiposity (assessed as leptin), and systemic inflammation [C-reactive peptide (CRP)] and negatively correlated with plasma levels of the insulin-sensitizing hormone adropin. Multiple regression analyses identified a strong association between circulating APOC3 and ANGPTL3 concentrations. Higher baseline plasma levels of both ANGPTL3 and APOC3 were associated with an increased risk for fructose-induced insulin resistance. Fish oil previously shown to prevent insulin resistance and hypertriglyceridemia in this model prevented increases of ANGPTL3 without affecting systemic inflammation (increased plasma CRP and interleukin-6 concentrations). ANGPTL3 RNAi lowered plasma concentrations of ANGPTL3, triglycerides (TGs), VLDL-C, APOC3, and APOE. These decreases were consistent with a reduced risk of atherosclerosis. In summary, dietary sugar-induced increases of circulating ANGPTL3 concentrations after metabolic dysregulation correlated positively with leptin levels, HOMA-IR, and dyslipidemia. Targeting ANGPTL3 expression with RNAi inhibited dyslipidemia by lowering plasma TGs, VLDL-C, APOC3, and APOE levels in rhesus macaques