5,732 research outputs found
Promotions and Game Attendance: A Case Study of Collegiate Hockey in the South
Undergraduate
Applie
The distinctive challenges and opportunities for creating leadership within social enterprises
Purpose
The purpose of this study is to present a systematic assessment of the distinctive challenges and opportunities associated with creating leadership within the realm of social enterprise. A modified and expanded form of Grintâs leadership lenses heuristic framework (i.e. person, position, process, performance, purpose and place) is used to examine and highlight what is particular about creating leadership in social enterprises by virtue of their distinctive missions, strategic contexts, legal forms and organisational structures and cultures. Based on this initial exploration, five research priorities are identified to better understand and then develop leadership practice in the social enterprise realm.
Design/methodology/approach
An enhanced heuristic framework for systematically examining leadership within the social enterprise research literature has been applied, drawing on the leadership practice literature. The application is illustrated through six instrumental case studies.
Findings
While there are a number of similarities between leading in the social enterprise realm and leading within the private, public and not-for-profit sectors, the levels of complexity, ambiguity and the lack of an established theoretical and practical knowledge base makes creating leadership in the social enterprise sector that much more challenging. On the positive side of the ledger, the fact that the purpose is at the core of social enterprise means that it is relatively easier to use the purpose to create a basis for common meaningful action, compared to leadership within the private and public sectors. Related to this, given the strongly local or âglocalâ nature of social enterprise, a ready opportunity exists for leaders to draw upon a place as a strategic resource in mobilising followers and other stakeholders. The novel, uncertain and pioneering nature of a social enterprise is also arguably more tolerant and accommodating of a leadership mindset that focuses on posing questions regarding âwickedâ problems compared to public, private for-profit and, indeed, traditional not-for-profit sector organisations.
Originality/value
As far as we can ascertain, this is the first systematic attempt to examine the distinctive challenges and opportunities associated with creating leadership within the social enterprise realm. The application of the heuristic framework leads to the identification of five key inter-related lines of empirical research into leadership practices within social enterprises.
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Patent Laws of the United States and Canada: Similarities and Differences
Canada-United States Economic Ties: The Technology Context, patent law in Canada and United States (similarities and differences
Some considerations on the disease rheumatism
The term Rheumatism is one of great antiquity,
going as far "back as the time of Hippocrates; and,
as the name indicates, it was employed by the early
authors to denote a
flowing, or catarrh.From these early times, down to the present
time, the term has been used to denote many and
various conditions; indeed, there is probably no
word in the whole, of medical nomenclature that has
been so freely used and abused. The name of rheumatism, like that of gout, carries with it the impress of humoral pathology.It cannot but be admitted that the modern view
defines the province of the disease with a clearness, such as never before was the case. This view
dispels all that mustiness and vagueness which are
part and parcel of such expressions as "constitutional", "diathesis". It does not permit the term
"rheumatism" to symbolise all forms of arthritis,
and all "cold" caused affections.A firmer mental grasp can be taken of this conception of the disease; it can be viewed as a composite whole. The conception of the disease in
short, is more scientific.This conception is the result of further knowledge of the disease obtained by clinical and pathological study.This further knowledge combined with pathological and clinical knowledge of other diseases has
resulted in the formation of the infective theory
as to the etiology and pathology of rheumatism.
No other theory gas yet been advanced which accounts so fully and completely for the phenomena
of rheumatism. No other theory has yet been advanced which is so near to being proved.It was remarked above that many writers of
text-books had placed rheumatism among the Infectious diseases, and that it marked an advance in
the right direction. There is, however, still
left something to be desired in the description of
the disease. With many writers, acute rheumatic
arthritis, or rheumatic fever, is still represented
as being typically the rheumatic process. The
rheumatism of childhood, or subacute rheumatism, does
not get dealt with as it ought. It cannot be insisted too strongly that subacute rheumatism is as
important, if not more important, than acute rheumatism.Some of the manifestations are mentioned chiefly as complications.
Some show a
lingering regard for pseudorheumatic affections. Even gout is described,
either immediately before, or immediately after,
rheumatism, by some writers.It must be remembered, however, that rheumatism is a disease of great antiquity; that it has
long held a position firmly established in the
medical mind, as well as the lay public mind;
that traditions die hard; that allowance must be
made for peculiar obstacles, beliefs, and prejudrices.If it be that rheumatism as a disease, is on
the eve of being put in its proper place in Medicine, it can, truly, be said that the history of
the progress of our knowledge of rheumatism affords
one more instance of -"Science moves, but slowly slowly,
Creeping on from point to point.
Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis
Objective: The recent Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) trial suggested that implantable cardioverter defibrillators (ICDs) do not reduce overall mortality in patients with non-ischaemic cardiomyopathy (NICM), despite reducing sudden cardiac death. We performed an updated meta-analysis to examine the impact of ICD therapy on mortality in NICM patients.
Methods: A systematic search for studies that examined the effect of ICDs on outcomes in NICM was performed. Our analysis compared patients randomised to an ICD with those randomised to no ICD, and examined the endpoint of overall mortality.
Results: Six primary prevention trials and two secondary prevention trials were identified that met the pre-specified search criteria. Using a fixed-effects model, analysis of primary prevention trials revealed a reduction in overall mortality with ICD therapy (RR 0.76, 95%âCI 0.65 to 0.91).
Conclusions: Although our updated meta-analysis demonstrates a survival benefit of ICD therapy, the effect is substantively weakened by the inclusion of the DANISH trialâwhich is both the largest and most recent of the analysed trialsâindicating that the residual pooled benefit of ICDs may reflect the risk of sudden death in older trials which included patients treated sub-optimally by contemporary standards. As such, these data must be interpreted cautiously. The results of the DANISH trial emphasise that there is no âone size fits allâ indication for primary prevention ICDs in NICM patients, and clinicians must consider age and comorbidity on an individual basis when determining whether a defibrillator is appropriate
Geometric stability of topological lattice phases.
The fractional quantum Hall (FQH) effect illustrates the range of novel phenomena which can arise in a topologically ordered state in the presence of strong interactions. The possibility of realizing FQH-like phases in models with strong lattice effects has attracted intense interest as a more experimentally accessible venue for FQH phenomena which calls for more theoretical attention. Here we investigate the physical relevance of previously derived geometric conditions which quantify deviations from the Landau level physics of the FQHE. We conduct extensive numerical many-body simulations on several lattice models, obtaining new theoretical results in the process, and find remarkable correlation between these conditions and the many-body gap. These results indicate which physical factors are most relevant for the stability of FQH-like phases, a paradigm we refer to as the geometric stability hypothesis, and provide easily implementable guidelines for obtaining robust FQH-like phases in numerical or real-world experiments.R. R. acknowledges support from the Sloan Foundation. G. M. acknowledges support from the Leverhulme Trust under grant no. ECF-2011-565, from the Newton Trust of the University of Cambridge, and from the Royal Society under grant UF120157. This work used computational and storage services associated with the Hoffman2 Shared Cluster provided by UCLA Institute for Digital Research and Educationâs Research Technology Group. Part of our numerical work was performed using the Darwin Supercomputer of the University of Cambridge High Performance Computing Service funded by Strategic Research Infrastructure Funding from the Higher Education Funding Council for England and funding from the Science and Technology Facilities Council.This is the final version of the article. It first appeared from Nature Publishing Group via http://dx.doi.org/10.1038/ncomms962
Barriers to the use of a diagnostic oral microbiology laboratory by general dental practitioners
OBJECTIVE: To identify barriers on the use of diagnostic microbiology facilities in general dental practice. DESIGN: A cross-sectional survey using a postal questionnaire. SETTING: Primary/secondary care interface between the diagnostic oral microbiology laboratory, University of Glasgow Dental Hospital and School, Glasgow and dental practitioners within the surrounding health boards, 1998. SUBJECTS: All GDPs (797) within Argyll and Clyde, Ayrshire and Arran, Lanarkshire and Greater Glasgow Health Boards. MAIN OUTCOME MEASURES: The responses were expressed as both absolute and relative frequencies. RESULTS: Responses were received from 430 (55%). The most frequent reason for failure to use the service was lack of information, with more than half of the respondents claiming to be unaware of the facility. Lack of request forms and sampling equipment were also viewed as barriers to using the service. CONCLUSIONS: The laboratory is failing to successfully communicate its role in addressing the growing burden of antibiotic resistance in the community and must be more proactive in encouraging appropriate use and increasing accessibility of the service to GDPs
Amperometric Screen-Printed Galactose Biosensor for Cell Toxicity Applications
© 2016, Copyright © Taylor & Francis Group, LLC. ABSTRACT: This paper reports the development and application of a biosensor for the amperometric determination of galactose in the presence of human hepatocellular carcinoma cells with and without a hepatotoxic agent. The biosensor was fabricated by drop-coating 1.5% cellulose acetate on a 3Ă3mm screen-printed carbon electrode followed by depositing 2 U of galactose oxidase. The electrodes dimensions were reduced to 3Ă0.5mm before measurements. Hepatocellular carcinoma cells were utilized for in vitro toxicity testing by evaluating the effect of paracetamol on galactose uptake. The amperometric responses to galactose indicated that the inhibition of uptake was directly proportional to the concentration of paracetamol following 24h of exposure to the hepatocellular carcinoma cells. These results demonstrate that the fabricated biosensor may be used for the real-time monitoring of cell metabolism and toxicity
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