6,284 research outputs found
A method of calculating compressible turbulent boundary layers
Equations of motion for calculating compressible turbulent boundary layer
Performance Evaluation of Sparse Matrix Multiplication Kernels on Intel Xeon Phi
Intel Xeon Phi is a recently released high-performance coprocessor which
features 61 cores each supporting 4 hardware threads with 512-bit wide SIMD
registers achieving a peak theoretical performance of 1Tflop/s in double
precision. Many scientific applications involve operations on large sparse
matrices such as linear solvers, eigensolver, and graph mining algorithms. The
core of most of these applications involves the multiplication of a large,
sparse matrix with a dense vector (SpMV). In this paper, we investigate the
performance of the Xeon Phi coprocessor for SpMV. We first provide a
comprehensive introduction to this new architecture and analyze its peak
performance with a number of micro benchmarks. Although the design of a Xeon
Phi core is not much different than those of the cores in modern processors,
its large number of cores and hyperthreading capability allow many application
to saturate the available memory bandwidth, which is not the case for many
cutting-edge processors. Yet, our performance studies show that it is the
memory latency not the bandwidth which creates a bottleneck for SpMV on this
architecture. Finally, our experiments show that Xeon Phi's sparse kernel
performance is very promising and even better than that of cutting-edge general
purpose processors and GPUs
Computer program for calculating laminar and turbulent boundary layer development in compressible flow
A computer program is described which performs a numerical integration of the equations of motion for a compressible two-dimensional boundary layer. Boundary layer calculations may be carried out for both laminar and turbulent flow for arbitrary Reynolds number and free stream Mach number distribution on planar or axisymmetric bodies with wall heating or cooling, longitudinal wall curvature, wall suction or blowing, and a rough or a smooth wall. A variety of options are available as initial conditions. The program can generate laminar initial conditions such as Falkner-Skan similarity solutions (so that initial wedge flows can be simulated including Blasius or stagnation point flow) or approximate equilibrium turbulent profiles. Alternatively, initial profile input data can be utilized
Sequence of the mouse Q4 class I gene and characterization of the gene product
The Q4 class I gene has been shown to participate
in gene conversion events within the mouse major
histocompatibility complex. Its complete genomic nucleotide
sequence has been determined. The 5' half of Q4
resembles H-2 genes more strongly than other Q genes.
Its 3' end, in contrast, is Q-like and contains a translational
stop signal in exon 5 which predicts a polypeptide with
an incomplete membrane spanning segment. The presence
of two inverted B1 repeats suggests that part of the Q4
gene may be mobile within the genome. Gene transfer experiments
have shown that the Q4 gene encodes a
ß2-microglobulin associated polypeptide of Mr 41 000. A
similar protein was found in activated mouse spleen cells.
The Q4 polypeptide was found to be secreted both by
spleen cells and by transfected fibroblasts and was not detectable
on the cell surface. Antibody binding and twodimensional
gel electrophoresis indicate that the Q4
molecule is identical to a mouse class I polypeptide, Qb-1,
which has been previously described
Welfare-aligned Sentience: Enhanced Capacities to Experience, Interact, Anticipate, Choose and Survive
The focus of this opinion is on the key features of sentience in animals which can experience different states of welfare encapsulated by the new term ‘welfare-aligned sentience’. This term is intended to exclude potential forms of sentience that do not enable animals in some taxa to have the subjective experiences which underlie different welfare states. As the scientific understanding of key features of sentience has increased markedly during the last 10 to 15 years, a major purpose here is to provide up-to-date information regarding those features. Eleven interconnected statements about sentience-associated body functions and behaviour are therefore presented and explained briefly. These statements are sequenced to provide progressively more information about key scientifically-supported attributes of welfare-aligned sentience, leading, in their entirety, to a more comprehensive understanding of those attributes. They are as follows: (1) Internal structure–function interactions and integration are the foundations of sentience; (2) animals possess a capacity to respond behaviourally to a range of sensory inputs; (3) the more sophisticated nervous systems can generate subjective experiences, that is, affects; (4) sentience means that animals perceive or experience different affects consciously; (5) within a species, the stage of neurobiological development is significant; (6) during development the onset of cortically-based consciousness is accompanied by cognitively-enhanced capacities to respond behaviourally to unpredictable postnatal environments; (7) sentience includes capacities to communicate with others and to interact with the environment; (8) sentience incorporates experiences of negative and positive affects; (9) negative and positive affective experiences ‘matter’ to animals for various reasons; (10) acknowledged obstacles inherent in anthropomorphism are largely circumvented by new scientific knowledge, but caution is still required; and (11) there is increasing evidence for sentience among a wider range of invertebrates. The science-based explanations of these statements provide the foundation for a brief definition of ‘welfare-aligned sentience’, which is offered for consideration. Finally, it is recommended that when assessing key features of sentience, the same emphasis should be given to positive and negative affective experiences in the context of their roles in, or potential impacts on animal welfare
High-resolution 3D weld toe stress analysis and ACPD method for weld toe fatigue crack initiation
Weld toe fatigue crack initiation is highly dependent on the local weld toe stress-concentrating geometry including any inherent flaws. These flaws are responsible for premature fatigue crack initiation (FCI) and must be minimised to maximise the fatigue life of a welded joint. In this work, a data-rich methodology has been developed to capture the true weld toe geometry and resulting local weld toe stress-field and relate this to the FCI life of a steel arc-welded joint. To obtain FCI lives, interrupted fatigue test was performed on the welded joint monitored by a novel multi-probe array of alternating current potential drop (ACPD) probes across the weld toe. This setup enabled the FCI sites to be located and the FCI life to be determined and gave an indication of early fatigue crack propagation rates. To understand fully the local weld toe stress-field, high-resolution (5 mu m) 3D linear-elastic finite element (FE) models were generated from X-ray micro-computed tomography (mu-CT) of each weld toe after fatigue testing. From these models, approximately 202 stress concentration factors (SCFs) were computed for every 1 mm of weld toe. These two novel methodologies successfully link to provide an assessment of the weld quality and this is correlated with the fatigue performance
Tail Docking of Canine Puppies: Reassessment of the Tail’s Role in Communication, the Acute Pain Caused by Docking and Interpretation of Behavioural Responses
Laws, regulations and professional standards increasingly aim to ban or restrict non-therapeutic tail docking in puppies. These constraints have usually been justified by reference to loss of tail participation in communication between dogs, the acute pain presumed to be caused during docking itself, subsequent experiences of chronic pain and heightened pain sensitivity, and the occurrence of other complications. These areas are reconsidered here. First, a scientifically robust examination of the dynamic functional foundations, sensory components and key features of body language that are integral to canine communication shows that the role of the tail has been greatly underestimated. More specifically, it shows that tail behaviour is so embedded in canine communication that docking can markedly impede unambiguous interactions between different dogs and between dogs and people. These interactions include the expression of wide ranges of both negative and positive emotions, moods and intentions that are of daily significance for dog welfare. Moreover, all docked dogs may experience these impediments throughout their lives, which challenges assertions by opponents to such bans or restrictions that the tail is a dispensable appendage. Second, and in contrast, a re-examination of the sensory capacities of puppies reveals that they do not consciously experience acute or chronic pain during at least the first week after birth, which is when they are usually docked. The contrary view is based on questionable between-species extrapolation of information about pain from neurologically mature newborns such as calves, lambs, piglets and human infants. These newborns can consciously experience pain in response to injury compared to neurologically immature puppies which remain non-sentient and unable to experience pain until about two weeks after birth. It is argued that the present analysis strengthens the rationale for bans or restrictions on docking the tails of puppies by clarifying which of several justifications previously used are and are not scientifically supportable. In particular, it highlights the major roles the tail plays in canine communication, as well as the lifetime handicaps to communication caused by docking. Thus, it is concluded that non-therapeutic tail docking of puppies represents an unnecessary removal of a necessary appendage and should therefore be banned or restricted
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