The maintenance of sex in bacteria is ensured by its potential to reload genes

Why sex is maintained in nature is a fundamental question in biology. Natural genetic transformation (NGT) is a sexual process by which bacteria actively take up exogenous DNA and use it to replace homologous chromosomal sequences. As it has been demonstrated, the role of NGT in repairing deleterious mutations under constant selection is insufficient for its survival, and the lack of other viable explanations have left no alternative except that DNA uptake provides nucleotides for food. Here we develop a novel simulation approach for the long-term dynamics of genome organization (involving the loss and acquisition of genes) in a bacterial species consisting of a large number of spatially distinct populations subject to independently fluctuating ecological conditions. Our results show that in the presence of weak inter-population migration NGT is able to subsist as a mechanism to reload locally lost, intermittently selected genes from the collective gene pool of the species through DNA uptake from migrants. Reloading genes and combining them with those in locally adapted genomes allow individual cells to re-adapt faster to environmental changes. The machinery of transformation survives under a wide range of model parameters readily encompassing real-world biological conditions. These findings imply that the primary role of NGT is not to serve the cell with food, but to provide homologous sequences for restoring genes that have disappeared from or become degraded in the local population.Comment: 16 pages with 3 color figures. Manuscript accepted for publication in Genetics (www.genetics.org

On the validity of the 5-dimensional Birkhoff theorem: The tale of an exceptional case

The 5-dimensional (5d) Birkhoff theorem gives the class of 5d vacuum space-times containing spatial hypersurfaces with cosmological symmetries. This theorem is violated by the 5d vacuum Gergely-Maartens (GM) space-time, which is not a representant of the above class, but contains the static Einstein brane as embedded hypersurface. We prove that the 5d Birkhoff theorem is still satisfied in a weaker sense: the GM space-time is related to the degenerated horizon metric of certain black-hole space-times of the allowed class. This result resembles the connection between the Bertotti-Robinson space-time and the horizon region of the extremal Reissner-Nordstrom space-time in general relativity.Comment: 13 pages; v2: title amended, to be published in Classical and Quantum Gravit

Effect Of Orius insidiosus (Hemiptera: Anthocoridae) And Spinosad (Conserve®) On Western Flower Thrips, Frankliniella occidentalis (Thysanoptera: Thripidae), Populations In Transvaal Daisy Flowers

Western flower thrips (WFT), Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), is a major insect pest of greenhouse-grown horticultural crops. Greenhouse producers typically apply insecticides to suppress WFT populations. However, continual reliance on insecticides can lead to the development of resistant in WFT populations. The insidious flower bug, Orius insidiosus (Say) (Hemiptera: Anthocoridae), is a commercially available predatory bug of WFT that offers an alternative to using insecticides for WFT suppression. Therefore, we investigated the efficacy of one or two O. insidiosus adults compared to spray applications of the standard insecticide, spinosad (Conserve®) in suppressing WFT adult populations in transvaal daisy (Gerbera jamesonii), cut-flowers under greenhouse conditions. Percent adult WFT mortality was significantly lower when one or two O. insidiosus adults were released into the flowers (mean range: 32 to 34%; n=747), compared to the untreated and water control (8 to 9%; n=431). The highest percent mortality of WFT adults was associated with the spinosad (Conserve®) treatment (100%; n= 203)

Non-uniform Braneworld Stars: an Exact Solution

The first exact interior solution to Einstein's field equations for a static and non-uniform braneworld star with local and non-local bulk terms is presented. It is shown that the bulk Weyl scalar ${\cal U}(r)$ is always negative inside the stellar distribution, in consequence it reduces both the effective density and the effective pressure. It is found that the anisotropy generated by bulk gravity effect has an acceptable physical behaviour inside the distribution. Using a Reissner-N\"{o}rdstrom-like exterior solution, the effects of bulk gravity on pressure and density are found through matching conditions.Comment: 22 pages, 3 figures, version to be published in International Journal of Modern Physics D (IJMPD

A Spherically Symmetric Closed Universe as an Example of a 2D Dilatonic Model

We study the two-dimensional (2D) dilatonic model describing a massless scalar field minimally coupled to the spherically reduced Einstein-Hilbert gravity. The general solution of this model is given in the case when a Killing vector is present. When interpreted in four dimensions, the solution describes either a static or a homogeneous collision of incoming and outgoing null dust streams with spherical symmetry. The homogeneous Universe is closed.Comment: 5 pages, 2 figures, to appear in Physical Review

The geometry of the Barbour-Bertotti theories II. The three body problem

We present a geometric approach to the three-body problem in the non-relativistic context of the Barbour-Bertotti theories. The Riemannian metric characterizing the dynamics is analyzed in detail in terms of the relative separations. Consequences of a conformal symmetry are exploited and the sectional curvatures of geometrically preferred surfaces are computed. The geodesic motions are integrated. Line configurations, which lead to curvature singularities for $N\neq 3$, are investigated. None of the independent scalars formed from the metric and curvature tensor diverges there.Comment: 16 pages, 2 eps figures, to appear in Classical and Quantum Gravit

The inference of gene trees with species trees

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are tightly linked, they are seldom identical, because genes duplicate, are lost or horizontally transferred, and because alleles can co-exist in populations for periods that may span several speciation events. Building models describing the relationship between gene and species trees can thus improve the reconstruction of gene trees when a species tree is known, and vice-versa. Several approaches have been proposed to solve the problem in one direction or the other, but in general neither gene trees nor species trees are known. Only a few studies have attempted to jointly infer gene trees and species trees. In this article we review the various models that have been used to describe the relationship between gene trees and species trees. These models account for gene duplication and loss, transfer or incomplete lineage sorting. Some of them consider several types of events together, but none exists currently that considers the full repertoire of processes that generate gene trees along the species tree. Simulations as well as empirical studies on genomic data show that combining gene tree-species tree models with models of sequence evolution improves gene tree reconstruction. In turn, these better gene trees provide a better basis for studying genome evolution or reconstructing ancestral chromosomes and ancestral gene sequences. We predict that gene tree-species tree methods that can deal with genomic data sets will be instrumental to advancing our understanding of genomic evolution.Comment: Review article in relation to the "Mathematical and Computational Evolutionary Biology" conference, Montpellier, 201