Keberkesanan aktiviti dakwah dalam aplikasi tiktok terhadap akhlak mahasiswa

This trend of modernization is getting more lively with unlimited sharing. The dai need to be aware that their duties not only in the real world but also in the virtual world need to be continued so that they can preach with the will of mad'u but still remain with the concept of Amar maaruf nahi mungkar. The TikTok application is a new space for dais to venture into a more creative da'wah field. This study aims to examine the involvement of students in preaching on the Tiktok application. This study was conducted using a quantitative approach which is in the form of a survey. This study uses a quantitative method which is a survey based on instruments submitted through a questionnaire. The instrument distribution method involved a total of 45 respondents among specialized students at the Faculty of Islamic Studies Civilization, KUIS. This study shows that Tiktok can be used for preaching purposes such as live, video, and others. This, finds the effectiveness of online preaching, especially the Tiktok application on the morals of students, and should be emphasized by every student. The researcher hopes that future researchers can study the effectiveness of preaching in the YouTube application against families to achieve greater objectives and more extensive research findings

Identifying Lung Cancer Using CT Scan Images Based On Artificial Intelligence

Lung cancer appears to be the common reason behind the death of human beings at some stage on the planet. Early detection of lung cancers can growth the possibility of survival amongst human beings. The preferred 5-years survival rate for lung most cancers sufferers will increase from 16% to 50% if the disease is detected in time. Although computerized tomography (CT) is frequently more efficient than X-ray. However, the problem regarded to merge way to time constraints in detecting this lung cancer concerning the numerous diagnosing strategies used. Hence, a lung cancer detection system that usage of image processing is hired to categorize lung cancer in CT images. In image processing procedures, procedures like image pre-processing, segmentation, and have extraction are mentioned intimately. This paper is pointing to set off the extra precise comes approximately through making use of distinctive improve and department procedures. In this proposal paper, the proposed method is built in some filter and segmentation that pre-process the data and classify the trained data. After the classification and trained WONN-MLB method is used to reduce the time complexity of finding result. Therefore, our research goal is to get the maximum result of lung cancer detection

Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis

South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome sequencing, followed by bioinformatic analysis using a commercial software package to determine resistance to selected drugs used for Mycobacterium tuberculosis treatment in our setting. Whole genome sequencing shows potential as a diagnostic platform for the detection of drug resistance in Mycobacterium tuberculosis with the provision of information for several drugs simultaneously

Drug resistant tuberculosis in Africa: Current status, gaps and opportunities

Background: The World Health Organization End TB Strategy targets for 2035 are ambitious and drug resistant tuberculosis is an important barrier, particularly in Africa, home to over a billion people. Objective: We sought to review the current status of drug resistant tuberculosis in Africa and highlight key areas requiring improvement. Methods: Available data from 2016 World Health Organization global tuberculosis database were extracted and analysed using descriptive statistics. Results: The true burden of drug resistant tuberculosis on the continent is poorly described with only 51% of countries having a formal survey completed. In the absence of this data, modelled estimates were used and reported 92 629 drug resistant tuberculosis cases with 42% of these occurring in just two countries: Nigeria and South Africa. Of the cases estimated, the majority of patients (70%) were not notified, representing ‘missed cases’. Mortality among patients with multi-drug resistant tuberculosis was 21%, and was 43% among those with extensively drug resistant tuberculosis. Policies on the adoption of new diagnostic tools was poor and implementation was lacking. A rifampicin result was available for less than 10% of tuberculosis cases in 23 of 47 countries. Second-line drug resistance testing was available in only 60% of countries. The introduction of the short multi-drug resistant tuberculosis regimen was a welcome development, with 40% of countries having implemented it in 2016. Bedaquiline has also been introduced in several countries. Conclusion: Drug resistant tuberculosis is largely missed in Africa and this threatens prospects to achieve the 2035 targets. Urgent efforts are required to confirm the true burden of drug resistant tuberculosis in Africa. Adoption of new tools and drugs is essential if the 2035 targets are to be met

Fundamental of Entrepreneurship ENT 300 : Bottle Up! / Afiqah Amran... [et al.]

Basically, our company is basically introducing a new way to reduce the expenses of any household appliances by buying less and earn more whereby in a business context, it is a win-win situation between a provider and the buyer. In a much more wider scope, our business insist to highlight the concept of 3R which is reuse, reduce and recycle and also we prohibited the use of plastic as it can pollute the environment. With that, to develop a more thriving and triumph company, we have asserted all of our objectives to make it as a benchmark to reach all of our goals as a successful and acknowledge company that is known to others because we striving for the excellency in terms of our customers' need and the quality of our products which the chemical are toxic-free and affordable in price for everyone to buy

Evaluation of preparation times of waveone gold reciprocating instruments compared to two analogous counterparts

Manufacturers are constantly developing new products to optimise endodontic treatment. These newer file systems are often associated with increasing expenditure of instrumentation and can affect the cost effectiveness of root canal treatment. Recently, companies have emerged that claim to have successfully reproduced many of the more established endodontic file systems manufactured by Dentsply Sirona (Ballaigues, Switzerland). EdgeEndo (Albuquerque, New Mexico, USA) and Pac- Dent (Brea, CA, USA), which manufacture files similar in design to that of Dentsply Sirona, claim that they are similar and sell them at a lower price. A performance comparison of the replica file systems to their original is of clinical importance. The aim of this ex vivo study was to compare the total glide path and canal preparation times of WaveOne Gold Glider (Dentsply Sirona) combined with the Primary WaveOne Gold (Dentsply Sirona), Edge GlidePath (Edge Endo, Albuquerque, New Mexico, USA) followed by the Primary EdgeOne Fire (EdgeEndo); and One File G Glide Path (Pac-Dent, Brea, CA, USA) file combined with the Primary One File G (Pac-Dent) Shaping file. Sixty curved untreated canals of extracted, human, mandibular molars were randomly divided into three groups of 20 canals each for mechanical glide path enlargement and root canal shaping. Group 1 (WaveOne Gold Glider + Primary WaveOne Gold); Group 2 (Edge Glide- Path + Primary EdgeOne Fire); and Group 3 (One File G Reciprocating Glide Path File + Primary One File G Reciprocating shaping file). The total time taken to prepare a glide path and to complete the root canal preparation of each canal was recorded (in seconds) by means of an iPhone stopwatch (Apple Inc., Cupertino, California). The time taken to change files was not recorded. Throughout the instrumentation process, RC Prep was used as a lubricant, and 5 mL 3% sodium hypochlorite was used as irrigation solution. Mean and standard deviations were determined for each group, and analysis of variance was used to statistically compare the mean glide path preparation times for the three groups. The fastest final canal preparation time was achieved by WOGG/PWOG (41.78±10.58 s), followed by OFGP/ POFS (42.02±12.16 s) and then EGP/PEOF (42.49± 10.44 s). There were no statistically significant differences between the canal preparation times of the three combination groups (p>0.05).https://www.sada.co.za/the-sadjam2022Odontolog

Antimicrobial activity analysis of extracts of Acacia modesta, Artimisia absinthium, Nigella sativa and Saussurea lappa against Gram positive and Gram negative microorganisms

Antimicrobial activity of extracts of certain herbs including Acacia modesta (leaf and stem), Artimisia absinthium (leaf and stem), Nigella sativa (seeds) and i (root) was evaluated against three Gram positive and two Gram negative microorganisms. The Gram positive organisms included Bacillus subtalis (ATCC 6633), Entereococcus faecalis (ATCC 14506) and Staphylococcus aureus (ATCC 6538) and the Gram negative organisms included Pseudomonas aeruginosa (ATCC 27853) and Salmonella typhi (ATCC 14028). Methanolic, hot water and cold water extracts of these plants were taken for antibacterial assay through Discs agar diffusion technique using commercial filter paper discs applied on inoculated Muellar Hinton agar plates. The objective of this study was to explore the curative powers of these herbs that exist in nature as a tool to counter disease causing agents. The maximum zone of inhibition of 18 mm of methanolic extract of N. sativa was observed against B. subtalis and S. aureus. Similarly, the maximum zone of inhibition of 18 mm of cold water extract of N. sativa against S. aureus and methanolic extract of Saussurea lappa against S. aureus and Pseudomonas aeruginosa was also observed. The antibacterial action was compared with the effect of ceftriaxone, ceftriaxone sodium, cefuroxine, ciprofloxacin, gentamycine, levofloxacin, metronidazole and tranexamic acid that were used as standered drugs. Based on the results obtained in this study, it may be concluded that plant extracts of A. modesta, A. absinthium, N. sativa and Saussurea lappa have a stronger and broader spectrum of antimicrobial activity against a number of food borne bacteria.Key words: Herbs, methanolic extract, Acacia modesta, Bacillus subtalis, gentamycine, gram negative, gram positive

Iqbal Haroon Master, 5 December 1962-15 January 2021

No abstract available.http://www.samj.org.zadm2022Medical Microbiolog

The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design.

During recent decades, Bangladesh has experienced a rapid epidemiological transition from communicable to non-communicable diseases. Coronary heart disease (CHD), with myocardial infarction (MI) as its main manifestation, is a major cause of death in the country. However, there is limited reliable evidence about its determinants in this population. The Bangladesh Risk of Acute Vascular Events (BRAVE) study is an epidemiological bioresource established to examine environmental, genetic, lifestyle and biochemical determinants of CHD among the Bangladeshi population. By early 2015, the ongoing BRAVE study had recruited over 5000 confirmed first-ever MI cases, and over 5000 controls "frequency-matched" by age and sex. For each participant, information has been recorded on demographic factors, lifestyle, socioeconomic, clinical, and anthropometric characteristics. A 12-lead electrocardiogram has been recorded. Biological samples have been collected and stored, including extracted DNA, plasma, serum and whole blood. Additionally, for the 3000 cases and 3000 controls initially recruited, genotyping has been done using the CardioMetabochip+ and the Exome+ arrays. The mean age (standard deviation) of MI cases is 53 (10) years, with 88 % of cases being male and 46 % aged 50 years or younger. The median interval between reported onset of symptoms and hospital admission is 5 h. Initial analyses indicate that Bangladeshis are genetically distinct from major non-South Asian ethnicities, as well as distinct from other South Asian ethnicities. The BRAVE study is well-placed to serve as a powerful resource to investigate current and future hypotheses relating to environmental, biochemical and genetic causes of CHD in an important but under-studied South Asian population.The Gates Cambridge Trust has supported Dr Chowdhury. Epidemiological fieldwork in BRAVE has been supported by grants to investigators at the Cardiovascular Epidemiology Unit, University of Cambridge. The Cardiovascular Epidemiology Unit is underpinned by programme grants from the British Heart Foundation (RG/13/13/30194), the UK Medical Research Council (MR/L003120/1), and the UK National Institute of Health Research Cambridge Biomedical Research Centre. BRAVE has received support for genetic assays from the European Research Council (ERC-2010-AdG-20100317), European Commission Framework 7 (Grant Agreement number: 279233), and the Cambridge British Heart Foundation Centre for Excellence in Cardiovascular Science; We would like to acknowledge the contributions of the following individuals: Cardiology Research Group in Bangladesh Mohammad Afzalur Rahman, Mohammad Abdul Kader Akanda, M Atahar Ali, Mir Jamal Uddin, SM Siddiqur Rahman, Amal Kumar Choudhury, Md. Mamunur Rashid, Nazir Ahmed Chowdhury, Mohammad Abdullahel Baqui, Kajal Kumar Karmoker, Mohammad Golam Azam; Setting up/implementation of fieldwork in Bangladesh Abbas Bhuiya, Susmita Chowdhury, Kamrun Nahar, Neelima Das, Proshon Roy, Sumona Ferdous, Taposh Kumar Biswas, Abu Sadat Mohammad Sayed Sharif, Ranjit Shingha, Rose Jinnath Tomas, Babulal Parshei, Mabubur Rahman, Mohammad Emon Hossain, Akhirunnesa Mily, AK Mottashir Ahmed, Sati Chowdhury, Sushila Roy, Dipak Kanti Chowdhury, Swapan Kumar Roy; Epidemiological/statistical support in Cambridge Stephen Kaptoge, Simon Thompson, Angela Wood, Narinder Bansal, Anna Ramond, Clare Oliver-Williams, Marinka Steur, Linda O’Keeffe, Eleni Sofianopoulou, Setor Kunutsor, Donal Gorman, Oscar H Franco, Malcolm Legget, Pinal Patel, Marc Suhrcke, Sylvaine Bruggraber, Jonathan Powell; Data management Matthew Walker, Steve Ellis, Shawkat Jahangir, Habibur Rahman, Rifat Hasan Shammi, Shafqat Ullah, Mohammad Abdul Matin and Administration Beth Collins, Hannah Lombardi, Binder Kaur, Rachel Henry, Marilena Papanikolaou, Robert Smith, Abdul Wazed, Robert Williams, Julie Jenkins, Keith Hoddy.This is the final published version of the article. It was originally published in the European Journal of Epidemiology (Chowdhury R, et al., European Journal of Epidemiology, 2015, doi:10.1007/s10654-015-0037-2). The final version is available at http://dx.doi.org/10.1007/s10654-015-0037-

Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis : a cross-sectional and longitudinal study

BACKGROUND : Bedaquiline improves outcomes of patients with rifampicin-resistant and multidrug-resistant (MDR) tuberculosis; however, emerging resistance threatens this success. We did a cross-sectional and longitudinal analysis evaluating the epidemiology, genetic basis, and treatment outcomes associated with bedaquiline resistance, using data from South Africa (2015–19). METHODS : Patients with drug-resistant tuberculosis starting bedaquiline-based treatment had surveillance samples submitted at baseline, month 2, and month 6, along with demographic information. Culture-positive baseline and post-baseline isolates had phenotypic resistance determined. Eligible patients were aged 12 years or older with a positive culture sample at baseline or, if the sample was invalid or negative, a sample within 30 days of the baseline sample submitted for bedaquiline drug susceptibility testing. For the longitudinal study, the first surveillance sample had to be phenotypically susceptible to bedaquiline for inclusion. Whole-genome sequencing was done on bedaquiline-resistant isolates and a subset of bedaquiline-susceptible isolates. The National Institute for Communicable Diseases tuberculosis reference laboratory, and national tuberculosis surveillance databases were matched to the Electronic Drug-Resistant Tuberculosis Register. We assessed baseline resistance prevalence, mutations, transmission, cumulative resistance incidence, and odds ratios (ORs) associating risk factors for resistance with patient outcomes. FINDINGS : Between Jan 1, 2015, and July 31, 2019, 8041 patients had surveillance samples submitted, of whom 2023 were included in the cross-sectional analysis and 695 in the longitudinal analysis. Baseline bedaquiline resistance prevalence was 3·8% (76 of 2023 patients; 95% CI 2·9–4·6), and it was associated with previous exposure to bedaquiline or clofazimine (OR 7·1, 95% CI 2·3–21·9) and with rifampicin-resistant or MDR tuberculosis with additional resistance to either fluoroquinolones or injectable drugs (pre-extensively-drug resistant [XDR] tuberculosis: 4·2, 1·7–10·5) or to both (XDR tuberculosis: 4·8, 2·0–11·7). Rv0678 mutations were the sole genetic basis of phenotypic resistance. Baseline resistance could be attributed to previous bedaquiline or clofazimine exposure in four (5·3%) of 76 patients and to primary transmission in six (7·9%). Odds of successful treatment outcomes were lower in patients with baseline bedaquiline resistance (0·5, 0·3–1). Resistance during treatment developed in 16 (2·3%) of 695 patients, at a median of 90 days (IQR 62–195), with 12 of these 16 having pre-XDR or XDR. INTERPRETATION : Bedaquiline resistance was associated with poorer treatment outcomes. Rapid assessment of bedaquiline resistance, especially when patients were previously exposed to bedaquiline or clofazimine, should be prioritised at baseline or if patients remain culture-positive after 2 months of treatment. Preventing resistance by use of novel combination therapies, current treatment optimisation, and patient support is essential.National Institute for Communicable Diseases of South Africa.http://www.thelancet.com/infectionhj2023Medical Microbiolog