MOLECULAR ANALYSIS OF CHEMOKINE RECEPTOR TYPE 5 (CCR5) CODING REGIONS IN HIV-1\AIDS SUDANESE PATIENTS

Chemokine receptors are a subclass of seven transmembrane Gprotein coupled receptors, a number of which act as co-receptors with CD4 for HIV1 infection, different polymorphisms within chemokine receptor genes were found to associate with susceptibility to HIV-1 infection and its progression. Analysis of CCR5 for genetic variants in different populations has identified several rare alleles, however most detected polymorphisms in the CC- chemokine receptor 5 (CCR5) gene were specific to different populations

Stability of dental implants placed in healed bony sites of hyperlipidemic patients: A case series

Background: The effect of elevated levels of serum fats ­­-hyperlipidemia- on the long-term implant stability and bone quality has been heavily examined in animal-model studies. This human-based case series is the first clinical study which aimed at clinical and radiographic evaluation of dental implant stability and the changes in bone density in patients with high lipid profile. Materials and Methods: Twelve female patients, each had a single healed bony site which indicated for implantation together with high serum fasting (Low-density lipoprotein) LDL level (≥160 mg/dl) were included in this study. The clinical implant stability values (ISQ) which were measured using the Resonance Frequency Analysis (RFA) method, and CBCT changes were recorded at baseline and six months post-implant insertion. Results: All patients showed implant success after six months. There was a significant increase of implant stability after 6 months from (65.92 ± 6.39 ISQ) to (74.42±6.20 ISQ) (p<0.001)