646 research outputs found
Bank regulation, financial crisis and the announcement effects of seasoned equity offerings of US commercial banks
This paper studies the differences in the announcement effects of seasoned equity offerings (SEOs) of commercial banks and non-banks, and explores the influence of bank regulation and the financial crisis on such differences. We find that abnormal stock returns on SEO announcements for US commercial banks are significantly higher than those of non-banks, consistent with the hypothesis that bank regulations reduce the likelihood that bank SEOs signal overpriced equity. The propensity score matching-based difference-in-difference analysis indicates that the differences in stock returns between banks and non-banks decreased during the 2007–2009 financial crisis period and increased after the passage of the Dodd-Frank Act in 2010
DNA-Interacting Characteristics of the Archaeal Rudiviral Protein SIRV2_Gp1
Whereas the infection cycles of many bacterial and eukaryotic viruses have been characterized in detail, those of archaeal viruses remain largely unexplored. Recently, studies on a few model archaeal viruses such as SIRV2 (Sulfolobus islandicus rod-shaped virus) have revealed an unusual lysis mechanism that involves the formation of pyramidal egress structures on the host cell surface. To expand understanding of the infection cycle of SIRV2, we aimed to functionally characterize gp1, which is a SIRV2 gene with unknown function. The SIRV2_Gp1 protein is highly expressed during early stages of infection and it is the only protein that is encoded twice on the viral genome. It harbours a helix-turn-helix motif and was therefore hypothesized to bind DNA. The DNA-binding behavior of SIRV2_Gp1 was characterized with electrophoretic mobility shift assays and atomic force microscopy. We provide evidence that the protein interacts with DNA and that it forms large aggregates, thereby causing extreme condensation of the DNA. Furthermore, the N-terminal domain of the protein mediates toxicity to the viral host Sulfolobus. Our findings may lead to biotechnological applications, such as the development of a toxic peptide for the containment of pathogenic bacteria, and add to our understanding of the Rudiviral infection cycle.status: publishe
Quantifying the pathway and predicting spontaneous emulsification during material exchange in a two phase liquid system
Kinetic restriction of a thermodynamically favourable equilibrium is a common theme in materials processing. The interfacial instability in systems where rate of material exchange is far greater than the mass transfer through respective bulk phases is of specific interest when tracking the transient interfacial area, a parameter integral to short processing times for productivity streamlining in all manufacturing where interfacial reaction occurs. This is even more pertinent in high-temperature systems for energy and cost savings. Here the quantified physical pathway of interfacial area change due to material exchange in liquid metal-molten oxide systems is presented. In addition the predicted growth regime and emulsification behaviour in relation to interfacial tension as modelled using phase-field methodology is shown. The observed in-situ emulsification behaviour links quantitatively the geometry of perturbations as a validation method for the development of simulating the phenomena. Thus a method is presented to both predict and engineer the formation of micro emulsions to a desired specification
Appendix D. Results of repeated-measures analysis and ANOVA on stem growth using plant cohort (plants existed before the burns vs. only after), fire treatment, and block as independent variables.
Results of repeated-measures analysis and ANOVA on stem growth using plant cohort (plants existed before the burns vs. only after), fire treatment, and block as independent variables
Three-Dimensional Paper Microfluidic Devices Assembled Using the Principles of Origami
We report a method, based on the principles of origami (paper folding), for fabricating three-dimensional (3-D) paper microfluidic devices. The entire 3-D device is fabricated on a single sheet of flat paper in a single photolithographic step. It is assembled by simply folding the paper by hand. Following analysis, the device can be unfolded to reveal each layer. The applicability of the device to chemical analysis is demonstrated by colorimetric and fluorescence assays using multilayer microfluidic networks
Paper-Based Electrochemical Sensing Platform with Integral Battery and Electrochromic Read-Out
We report a battery-powered, microelectrochemical sensing
platform
that reports its output using an electrochromic display. The platform
is fabricated based on paper fluidics and uses a Prussian blue spot
electrodeposited on an indium-doped tin oxide thin film as the electrochromic
indicator. The integrated metal/air battery powers both the electrochemical
sensor and the electrochromic read-out, which are in electrical contact
via a paper reservoir. The sample activates the battery and the presence
of analyte in the sample initiates the color change of the Prussian
blue spot. The entire system is assembled on the lab bench, without
the need for cleanroom facilities. The applicability of the device
to point-of-care sensing is demonstrated by qualitative detection
of 0.1 mM glucose and H<sub>2</sub>O<sub>2</sub> in artificial urine
samples
Appendix C. Results of Kaplan-Meier survival curves analysis and logistic regression on survival using plant cohort, fire treatment, and block as predictors.
Results of Kaplan-Meier survival curves analysis and logistic regression on survival using plant cohort, fire treatment, and block as predictors
Appendix A. Verification of plant names and native status.
Verification of plant names and native status
Appendix B. Chi-square test results on plant naturalization patterns.
Chi-square test results on plant naturalization patterns
Paper-Based Electrochemical Sensing Platform with Integral Battery and Electrochromic Read-Out
We report a battery-powered, microelectrochemical sensing
platform
that reports its output using an electrochromic display. The platform
is fabricated based on paper fluidics and uses a Prussian blue spot
electrodeposited on an indium-doped tin oxide thin film as the electrochromic
indicator. The integrated metal/air battery powers both the electrochemical
sensor and the electrochromic read-out, which are in electrical contact
via a paper reservoir. The sample activates the battery and the presence
of analyte in the sample initiates the color change of the Prussian
blue spot. The entire system is assembled on the lab bench, without
the need for cleanroom facilities. The applicability of the device
to point-of-care sensing is demonstrated by qualitative detection
of 0.1 mM glucose and H<sub>2</sub>O<sub>2</sub> in artificial urine
samples
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