29,788 research outputs found

    Special tool kit aids heavily garmented workers

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    Triangular aluminum tool kit, filled with polyurethane is constructed to receive various tools and hold them in a snug but quick-release fit as an aid to heavily gloved workers. The kit is designed to allow mounting within easily accessable reach and to provide protection of the tools during storage

    Behaviour change interventions to influence antimicrobial prescribing: a cross-sectional analysis of reports from UK state-of-the-art scientific conferences

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    Background To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration has been recommended. We analysed major UK scientific research conferences to investigate AMS behaviour change intervention reporting. Methods Leading UK 2015 scientific conference abstracts for 30 clinical specialties were identified and interrogated. All AMS and/or antimicrobial resistance(AMR) abstracts were identified using validated search criteria. Abstracts were independently reviewed by four researchers with reported behavioural interventions classified using a behaviour change taxonomy. Results Conferences ran for 110 days with >57,000 delegates. 311/12,313(2.5%) AMS-AMR abstracts (oral and poster) were identified. 118/311(40%) were presented at the UKā€™s infectious diseases/microbiology conference. 56/311(18%) AMS-AMR abstracts described behaviour change interventions. These were identified across 12/30(40%) conferences. The commonest abstract reporting behaviour change interventions were quality improvement projects [44/56 (79%)]. In total 71 unique behaviour change functions were identified. Policy categories; ā€œguidelinesā€ (16/71) and ā€œservice provisionā€ (11/71) were the most frequently reported. Intervention functions; ā€œeducationā€ (6/71), ā€œpersuasionā€ (7/71), and ā€œenablementā€ (9/71) were also common. Only infection and primary care conferences reported studies that contained multiple behaviour change interventions. The remaining 10 specialties tended to report a narrow range of interventions focusing on ā€œguidelinesā€ and ā€œenablementā€. Conclusion Despite the benefits of behaviour change interventions on antimicrobial prescribing, very few AMS-AMR studies reported implementing them in 2015. AMS interventions must focus on promoting behaviour change towards antimicrobial prescribing. Greater focus must be placed on non-infection specialties to engage with the issue of behaviour change towards antimicrobial use

    Two-sample Bayesian Nonparametric Hypothesis Testing

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    In this article we describe Bayesian nonparametric procedures for two-sample hypothesis testing. Namely, given two sets of samples y(1)ā€…ā€Š\mathbf{y}^{\scriptscriptstyle(1)}\;\stackrel{\scriptscriptstyle{iid}}{\s im}ā€…ā€ŠF(1)\;F^{\scriptscriptstyle(1)} and y(2)ā€…ā€Š\mathbf{y}^{\scriptscriptstyle(2 )}\;\stackrel{\scriptscriptstyle{iid}}{\sim}ā€…ā€ŠF(2)\;F^{\scriptscriptstyle( 2)}, with F(1),F(2)F^{\scriptscriptstyle(1)},F^{\scriptscriptstyle(2)} unknown, we wish to evaluate the evidence for the null hypothesis H0:F(1)ā‰”F(2)H_0:F^{\scriptscriptstyle(1)}\equiv F^{\scriptscriptstyle(2)} versus the alternative H1:F(1)ā‰ F(2)H_1:F^{\scriptscriptstyle(1)}\neq F^{\scriptscriptstyle(2)}. Our method is based upon a nonparametric P\'{o}lya tree prior centered either subjectively or using an empirical procedure. We show that the P\'{o}lya tree prior leads to an analytic expression for the marginal likelihood under the two hypotheses and hence an explicit measure of the probability of the null Pr(H0āˆ£{y(1),y(2)})\mathrm{Pr}(H_0|\{\mathbf {y}^{\scriptscriptstyle(1)},\mathbf{y}^{\scriptscriptstyle(2)}\}\mathbf{)}.Comment: Published at http://dx.doi.org/10.1214/14-BA914 in the Bayesian Analysis (http://projecteuclid.org/euclid.ba) by the International Society of Bayesian Analysis (http://bayesian.org/
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