Reproductive changes among women in their 40s : A cross-sectional study

Introduction: The aim was to describe and compare changes in the reproductive pattern of women in their 40s observed over a decade in Scandinavia. Material and Methods: Cross-sectional study using the total population of women aged 40-49 years between 2008-2018 in Denmark, Norway and Sweden (on average n = 1.5 million). Aggregated data concerning birth and induced abortion rate were collected and analyzed from national health registers. National data on redeemed prescriptions of hormonal contraceptives in the three countries were collected from prescription registers. Births after spontaneous and assisted conceptions were identified by using cross-linked data on deliveries from the Medical Birth Registers and National Registers of Assisted Reproduction in the three countries. Results: Use of hormonal contraception increased among women aged 40-44 years in Denmark from 24% to 31%, in Sweden from 27% to 30%, and in Norway from 22% to 24%. The levonorgestrel-releasing intrauterine device was the most frequently used method in all countries. Birth rates among women 40-44 years increased continuously from 9.5 to 12/1000 women in Denmark and from 11.7 to 14.3/1000 in Sweden, but remained stable in Norway at similar to 11/1000 women. There was a doubling of assisted conceptions in Denmark from 0.71 to 1.71/1000 women, Sweden from 0.43 to 0.81/1000 and Norway from 0.25 to 0.53/1000 women 40-49 years of age. Sweden had the highest induced abortion rate (7.7 to 8.1/1000 women) in women aged 40-49 years during the study period. Conclusions: From 2008 to 2018, birth rates continuously increased among women aged 40-49 years in Denmark and Sweden and births resulting from assisted reproductive technology doubled in all three countries.Peer reviewe

Contraception and unplanned pregnancies

Aims: The overall aim of this thesis was to describe the relationship between contraceptive use, abortion, birth and fertility rates among women in different age groups in Sweden and the other Nordic countries. Material and methods: Data on contraception, fertility, birth, and abortion from 1975-2015 was collected from national databases in the five Nordic countries Denmark, Finland, Iceland, Norway and Sweden (Paper I-III). In Paper IV data on reproductive health and socio-economic status (SES) was collected mainly from questionnaires sent to four cohorts of 19-year-old women resident in Gothenburg between 1981 and 2011. Paper V was a multicentre randomised controlled equivalence study where the impact of immediate versus delayed insertion of an etonogestrel releasing contraceptive implant on complete abortion rates after a medical abortion was evaluated. Results: The user rates of hormonal contraceptives and a copper intrauterine device among all women aged 15-49 years in the Nordic countries varied between 31% and 44%. The highest use was in Denmark and the lowest in Iceland. Combined hormonal contraceptives (CHC) were the most common methods. A small increase of long-acting reversible contraception (LARC) was seen. The user rates of hormonal contraceptives among 18-19 years old teenagers varied between 54% and 63%. CHC were the most common methods, but LARC increased more than in the group of women aged 15-49 years. The overall abortion rates in the Nordic countries fell during the study period. The average fertility and birth rates in the Nordic countries remained stable. Teenage birth and abortion rates declined continuously 1975-2015. There was no clear correlation between higher overall hormonal contraception prevalence and lower abortion rate. Instead other factors have to be considered, such as differences in the proportions of different types of hormonal contraceptives and prevalence in specific age groups. Lower contraceptive use in low SES areas compared to middle and high SES areas was detected in the most recent assessment of 19 years-old women. Equivalence was established for the two insertion modes of a contraceptive implant. Conclusions: On a global scale the Nordic countries have a high prevalence of contraceptive use, low abortions rates and a stable fertility rate, except for teenagers where a steady decline in both births and abortions was found. An association between low SES and low contraceptive use among 19-year-olds in the most recent assessment was found which might imply widening inequalities. A contraceptive implant can be inserted on the same day as administration of mifepristone for early medical abortion without hampering the abortion. It has the potential to increase the number of women who can receive the most effective methods of contraception at the time of abortion

Ecological study on the use of hormonal contraception, abortions and births among teenagers in the Nordic countries

Objectives Compare hormonal contraceptive use, birth and abortion rates among teenagers in the Nordic countries. A secondary aim was to explore plausible explanations for possible differences between countries. Design Ecological study using national registry data concerning births and abortions among all women aged 15-19 years residing in Denmark, Finland, Iceland, Norway and Sweden 2008-2015. Age-specific data on prescriptions for hormonal contraceptives for the period 2008-2015 were obtained from national databases in Denmark, Norway and Sweden. Setting Denmark, Finland, Iceland, Norway and Sweden. Participants Women 15-19 years old in all Nordic countries (749 709) and 13-19 years old in Denmark, Norway and Sweden (815 044). Results Both annual birth rates and abortion rates fell in all the Nordic countries during the study period. The highest user rate of hormonal contraceptives among 15-19-year-olds was observed in Denmark (from 51% to 47%) followed by Sweden (from 39% to 42%) and Norway (from 37% to 41%). Combined oral contraceptives were the most commonly used methods in all countries. The use of long-acting reversible contraceptives (LARC), implants and the levonorgestrel-releasing intrauterine systems, were increasing, especially in Sweden and Norway. In the subgroup of 18-19-year-old teenagers, the user rates of hormonal contraceptives varied between 63% and 61% in Denmark, 56% and 61% in Norway and 54% and 56% in Sweden. In the same subgroup, the steepest increase of LARC was seen, from 2% to 6% in Denmark, 2% to 9% in Norway and 7% to 17% in Sweden. Conclusions Birth and abortion rates continuously declined in the Nordic countries among teenagers. There was a high user rate of hormonal contraceptives, with an increase in the use of LARC especially among the oldest teenagers.Peer reviewe