Corneal Dermoid

A 20 years old boy presented with left corneal mass. The mass involved entire cornea extending to the sclera. The mass had a skin like surface and protruded outside the palpebral aperture. The eye with the mass was excised .The histopathology report confirmed the diagnosis of corneal dermoid. This late presentation of huge corneal dermoid extending to sclera is first such report in the literature

Over the counter ophthalmic drug misuse, are we aware?

Aim: To investigate the misuse of ‘over the counter’ ophthalmic medications in our city. Method: Responses of a structured questionnaire covering various aspects of over the counter drug use was obtained from pharmacy workers in and around our city. Results: Eighty nine pharmacy workers took part in this cross–sectional study. An average number of seven patients per day with ophthalmic complaints were seen by the pharmacy workers. Dispensing over the counter was practiced by 89.9% of the pharmacists. The most common complaint of the patients visiting the pharmacy, was redness and itching (86.5%). Antibiotics (96.6%) were the most common eye drops dispensed over the counter, followed by steroids (55.1%), decongestants (54.1%), antibiotic-steroid combination eye drops (29.2%) and lubricants (16.8%). Awareness regarding complications of steroid use was seen in 40.6% of pharmacists. 6.7% pharmacists had seen patients with complications following use of over the counter medications. In our study, majority of the eye drops dispensed were prescription drugs. Conclusion: Availability of prescription eye drops over the counter is an immense public threat. Educating the pharmacist and the population can decrease ocular morbidity. Research into methods to effectively deal with over-the-counter drug misuse is required and law can be enforced based on the findings

Enhancement of magnetoresistance in manganite multilayers

Magnanite multilayers have been fabricated using La0.67Ca0.33MnO3 as the ferromagnetic layer and Pr0.7Ca0.3MnO3 and Nd0.5Ca0.5MnO3 as the spacer layers. All the multilayers were grown on LaAlO3 (100) by pulse laser deposition. An enhanced magnetoresistnace (defined (RH- R0)/R0) of more than 98% is observed in these multilayers. Also a low field magnetoresistance of 41% at 5000 Oe is observed in these multilayer films. The enhanced MR is attributed to the induced double exchange in the spacer layer, which is giving rise to more number of conducting carriers. This is compared by replacing the spacer layer with LaMnO3 where Mn exists only in 3+ state and no enhancement is observed in the La0.67Ca0.33MnO3 / LaMnO3 multilayers as double exchange mechanism can not be induced by external magnetic fields.Comment: 13 pages, 5 Figure

Chiral phase transition of (2+1)-flavor QCD

We present here results on the determination of the critical temperature in the chiral limit for (2+1)-flavor QCD. We propose two novel estimators of the chiral critical temperature where quark mass dependence is strongly suppressed compared to the conventional estimator using pseudo-critical temperatures. We have used the HISQ/tree action for the numerical simulation with lattices with three different temporal extent $N_{\tau}=$6, 8, 12 and varied the aspect ratio over the range $4 \leq N_{\sigma}/N_{\tau} \leq 8$. To approach the chiral limit, the light quark mass has been decreased keeping the strange quark mass fixed at its physical value. Our simulations correspond to the range of pion masses, 55 MeV $\leq m_{\pi} \leq$ 160 MeV.Comment: Prepared for the proceedings of Quark Matter 201

Enhancement of magnetoresistance in manganite multilayers

Magnanite multilayers have been fabricated using La0.67Ca0.33MnO3 as the ferromagnetic layer and Pr0.7Ca0.3MnO3 and Nd0.5Ca0.5MnO3 as the spacer layers. All the multilayers were grown on LaAlO3 (100) by pulse laser deposition. An enhanced magnetoresistnace (defined (RH- R0)/R0) of more than 98% is observed in these multilayers. Also a low field magnetoresistance of 41% at 5000 Oe is observed in these multilayer films. The enhanced MR is attributed to the induced double exchange in the spacer layer, which is giving rise to more number of conducting carriers. This is compared by replacing the spacer layer with LaMnO3 where Mn exists only in 3+ state and no enhancement is observed in the La0.67Ca0.33MnO3 / LaMnO3 multilayers as double exchange mechanism can not be induced by external magnetic fields.Comment: 13 pages, 5 Figure

Alterations in tumour suppressor gene p53 in human gliomas from Indian patients

Alterations in the tumour suppressor p53 gene are among the most common defects seen in a variety of human cancers. In order to study the significance of the p53 gene in the genesis and development of human glioma from Indian patients, we checked 44 untreated primary gliomas for mutations in exons 5-9 of the p53 gene by PCR-SSCP and DNA sequencing. Sequencing analysis revealed six missense mutations. The incidence of p53 mutations was 13.6% (6 of 44). All the six mutations were found to be located in the central core domain of p53, which carries the sequence-specific DNA-binding domain. These results suggest a rather low incidence but a definite involvement of p53 mutations in the gliomas of Indian patients

Chiral metals and entrapped insulators in a one-dimensional topological non-Hermitian system

In this work, we study many-body "steady states" that arise in the non-Hermitian generalization of the noninteracting Su-Schrieffer-Heeger model at a finite density of fermions. We find that the hitherto known phase diagrams for this system, derived from the single-particle gap closings, in fact correspond to distinct nonequilibrium phases, which either carry finite currents or are dynamical insulators where particles are entrapped. Each of these have distinct quasiparticle excitations and steady-state correlations and entanglement properties. Looking at finite-sized systems, we further modulate the boundary to uncover the topological features in such steady states, particularly the emergence of leaky boundary modes. Using a variety of analytical and numerical methods, we develop a theoretical understanding of the various phases and their transitions, and we uncover the rich interplay of nonequilibrium many-body physics, quantum entanglement, and topology in a simple looking yet rich model system

Comparison of chewing ability, oral health related quality of life and nutritional status before and after insertion of complete denture amongst edentulous patients in a Dental College of Pune

BACKGROUND: The relationship between tooth loss and nutritional intake is important. As people age, their diminished physical capacity and  decreased income adversely affect their ability to maintain their teeth. The aim of the study was to assess and compare the chewing ability, oral health related quality of life and nutritional status before and after  fabrication and insertion of complete denture amongst edentulous participants in a dental college.MATERIAL AND METHODS: Non Randomized Intervention study. The study population consisted of 42 participants (16 females and 26 males), aged 50 years and above. Prior to commencement of the study, informed consent was obtained and validation and reliability test of the  questionnaire were done. The data for chewing ability, GOHAI and  nutritional status assessment was recorded at baseline, 3rd, 6th and12th month after denture fabrication and insertion. The statistical  comparisons were performed by repeated measure ANOVA and Chi-square test. P value<0.05 was considered as statistically significant.RESULTS: Chewing ability, GOHAI, BMI (Body Mass Index) and data from Food-intake questionnaire showed statistically significant improvement from baseline to 6th month but no statistically significant improvement was observed from 6th month to 12th month. Nutritive value of food (protein, energy and fat) showed no significant difference over a period of 12 months (p<0.05).Conclusion: Thus, it was concluded that the intervention (denture insertion) was effective in increasing the chewing ability, body weight, food-intake, and oral health related quality of life.KEYWORDS: nutrition, edentulousness, OHQoL, GOHAI, chewing abilit