2,655 research outputs found
Multi-element cylindrical electrostatic lens systems for focusing and controlling charged particles
This paper describes theoretical modelling of electrostatic lenses based on
3, 4 and 5 closely spaced cylindrical electrodes, respectively. In each case,
modelling is carried out numerically using commercial packages SIMION and
LENSYS, and a variety of performance parameters are obtained. These include the
magnification, the 3rd order spherical and chromatic aberration coefficients.
Special cases such as zoom lens (i.e., lenses whose magnification may be
changed without losing focus) are considered. Results are obtained as a
function of the ratios of the electrode lengths and gaps, and as a function of
ratios of the controlling voltages.
As a result, it is shown that how a multi-element lens system can be operated
with the whole focal properties in a useful mode for using in experimental
studies.Comment: 20 pages, 15 figure
Resurrecting the Dead (Molecules)
Biological molecules, like organisms themselves, are subject to genetic drift and may even become âextinctâ. Molecules that are no longer extant in living systems are of high interest for several reasons including insight into how existing life forms evolved and the possibility that they may have new and useful properties no longer available in currently functioning molecules. Predicting the sequence/structure of such molecules and synthesizing them so that their properties can be tested is the basis of âmolecular resurrectionâ and may lead not only to a deeper understanding of evolution, but also to the production of artificial proteins with novel properties and even to insight into how life itself began
Virus-like particles derived from bacteriophage MS2 as antigen scaffolds and RNA protective shells
The versatile potential of bacteriophage MS2-derived virus-like particles (VLPs) in medical biotechnology has been extensively studied during the last 30 years. Since the first reports showing that MS2 VLPs can be produced at high yield and relatively easily engineered, numerous applications have been proposed. Particular effort has been spent in developing MS2 VLPs as protective capsules and delivery platforms for diverse molecules, such as chemical compounds, proteins and nucleic acids. Among these, two are particularly noteworthy: as scaffolds displaying heterologous epitopes for vaccine development and as capsids for encapsulation of foreign RNA. In this review, we summarize the progress in developing MS2 VLPs for these two areas
Angles of vision: digital storytelling on the cosmic tide?
In this report, a collaboration between Robert Gordon University and the University of the Highlands and Islands Institute for Northern Studies, the authors bring together findings from four workshops hosted as part of the My Orkney Story project. It aims to address the opportunities and challenges of developing digital storytelling platforms through the lens of Orkney as a case study. However, the findings from this report are also intended to have a wider relevancy to the development and implementation of digital story platforms at a local and international level
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