44 research outputs found

    The Need For Judicial Activism Acceptance Speech

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    Honorable President, Dean of the Shepard Broad Law Center, members of the faculty, respected students, distinguished guests, ladies and gentlemen

    Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector

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    A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at = 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb, , and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion

    Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

    Accuracy versus precision in boosted top tagging with the ATLAS detector

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    Abstract The identification of top quark decays where the top quark has a large momentum transverse to the beam axis, known as top tagging, is a crucial component in many measurements of Standard Model processes and searches for beyond the Standard Model physics at the Large Hadron Collider. Machine learning techniques have improved the performance of top tagging algorithms, but the size of the systematic uncertainties for all proposed algorithms has not been systematically studied. This paper presents the performance of several machine learning based top tagging algorithms on a dataset constructed from simulated proton-proton collision events measured with the ATLAS detector at √ s = 13 TeV. The systematic uncertainties associated with these algorithms are estimated through an approximate procedure that is not meant to be used in a physics analysis, but is appropriate for the level of precision required for this study. The most performant algorithms are found to have the largest uncertainties, motivating the development of methods to reduce these uncertainties without compromising performance. To enable such efforts in the wider scientific community, the datasets used in this paper are made publicly available.</jats:p

    Status and Distribution of Amphibians in Tolipir National Park, Pakistan

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    The herpetofauna was surveyed from January to December 2018 along the elevation gradient 1367 m to 2617 m, asl in Tolipir National Park. The whole area was sampled by taking 52 quadrates. Three amphibian species were recorded using the visual encounter method in an area of 52 km2. This study provides baseline data for spatial distribution of amphibians in Tolipir National Park and provides previously unavailable baseline information for use in the development of a preliminary conservation schedule

    Predictive Model for Lung Cancer Detection

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    Lung cancer is the result of cells that develop widely in one or both of the lungs. Lung cancer is diagnosed in two ways non-small cell lung cancer and small cell lung cancer. Too late, lung cancer has been the main cause of death worldwide. If detected successfully in the early stages lung cancer allows for many treatment options, decrease the risk of aggressive surgery an increased rate of survival. So the early diagnosis of lung cancer is very important. Our aims and objectives to develop this system is to detect the lung cancer in an input image and shows that image of lung is normal or abnor0mal. Here we proposed a system where radiologist login with system by entering his/her email and password. Radiologist fill patient form with coordination of patient and upload CT scan image of lungs in predictive model for lung cancer detection and get output and print report .Several image processing techniques that we have used to design this system, Image Pre-processing, Image Segmentation, Image Filtering, Dilation, Image Filling, Feature Extraction Neural Network and Neuro Fuzzy classification algorithm is used for image classification. MATLAB is used to designed detection part of system

    Satellite Navigation Systems: Policy, Commercial and Technical Interaction Testing The DVRS National GPS-RTK Network

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    Abstract In this study, the Dubai Virtual Reference System (DVRS), a national RTK network, is examined. The network started its service in March 2002 with the objective of obtaining the cmlevel positioning accuracy throughout the Emirate of Dubai, UAE. The DVRS network architecture is first addressed. The estimation technique of processing the observables in a state space mode transferred to the observation domain is next described, followed by presenting procedure and results of comprehensive testing of the DVRS system. The system absolute accuracy was first tested by surveying a set of points of well known coordinates and comparing the known and DVRS results. Relative positioning accuracy was tested by studying differences between distances derived from the DVRS estimated points against their pre-determined precise values. Precision and repeatability were investigated by comparing results of point coordinates determined by the DVRS in different sessions with varying conditions. System availability, reliability, and robustness, particularly in case of failure of one of the reference stations, were also investigated. In addition, the performance of the network approach against that of employing a single reference station was investigated. Results prove system reliability and show its advantages and positioning accuracy, which is typically 1-5 cm

    Sincerely

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    Doctor rerum naturalium (Dr. rer. nat) genehmigt durch die Fakultät für Naturwissenschaften der Otto-Von-Guericke-Universität Magdebur
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