Rural water supply in Africa: Building blocks for handpump sustainability

Rural water supplies in sub-Saharan Africa, particularly those relying on handpumps, often demonstrate low levels of sustainability. This book is designed to assist those responsible for planning, implementing and supporting rural water supply programmes to increase sustainability. Its primary aims are to raise awareness of issues that affect sustainability and the interrelationship between them, provide options for addressing these using examples, and describe how these options can be implemented. The importance of a programmatic approach to the delivery of rural water services is emphasized, as is the need for ongoing institutional support for community management and consideration of alternative management models. The book does not prescribe a 'one size fits all' solution but encourages a flexible, holistic approach to decision-making to achieve sustainable outcomes

Emergency infrastructure planning

This paper is based on research recently undertaken at WEDC to develop guidelines for the planning and management of emergency sanitation programmes

The Triton: Design concepts and methods

During the design of the C & P Aerospace Triton, a few problems were encountered that necessitated changes in the configuration. After the initial concept phase, the aspect ratio was increased from 7 to 7.6 to produce a greater lift to drag ratio (L/D = 13) which satisfied the horsepower requirements (118 hp using the Lycoming O-235 engine). The initial concept had a wing planform area of 134 sq. ft. Detailed wing sizing analysis enlarged the planform area to 150 sq. ft., without changing its layout or location. The most significant changes, however, were made just prior to inboard profile design. The fuselage external diameter was reduced from 54 to 50 inches to reduce drag to meet the desired cruise speed of 120 knots. Also, the nose was extended 6 inches to accommodate landing gear placement. Without the extension, the nosewheel received an unacceptable percentage (25 percent) of the landing weight. The final change in the configuration was made in accordance with the stability and control analysis. In order to reduce the static margin from 20 to 13 percent, the horizontal tail area was reduced from 32.02 to 25.0 sq. ft. The Triton meets all the specifications set forth in the design criteria. If time permitted another iteration of the calculations, two significant changes would be made. The vertical stabilizer area would be reduced to decrease the aircraft lateral stability slope since the current value was too high in relation to the directional stability slope. Also, the aileron size would be decreased to reduce the roll rate below the current 106 deg/second. Doing so would allow greater flap area (increasing CL(sub max)) and thus reduce the overall wing area. C & P would also recalculate the horsepower and drag values to further validate the 120 knot cruising speed

The Freshman, vol. 5, no. 18

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

The Freshman, vol. 5, no. 17

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

Sensory-neuropathy-causing mutations in ATL3 cause aberrant ER membrane tethering

The endoplasmic reticulum (ER) is a complex network of sheets and tubules that is continuously remodeled. The relevance of this membrane dynamics is underscored by the fact that mutations in atlastins (ATLs), the ER fusion proteins in mammals, cause neurodegeneration. How defects in this process disrupt neuronal homeostasis is unclear. Using electron microscopy (EM) volume reconstruction of transfected cells, neurons, and patient fibroblasts, we show that hereditary sensory and autonomic neuropathy (HSAN)-causing ATL3 mutants promote aberrant ER tethering hallmarked by bundles of laterally attached ER tubules. In vitro, these mutants cause excessive liposome tethering, recapitulating the results in cells. Moreover, ATL3 variants retain their dimerization-dependent GTPase activity but are unable to promote membrane fusion, suggesting a defect in an intermediate step of the ATL3 functional cycle. Our data show that the effects of ATL3 mutations on ER network organization go beyond a loss of fusion and shed light on neuropathies caused by atlastin defects

The Ursinus Weekly, May 15, 1969

Student plea for relevance asserted at Skytop meeting • USGA endorses USC plan; Responsible assembly called - Mass meeting held; March called off • USC makes presentation to committee • Travelin\u27 II smash hit; Tomlinson huge success • Dr. Cyrus Gordon discloses discovery • Editorials: Post mortem - Campus Chest; Agency dilemma • Focus: Chuck Williams • Letters to the editor • Thieves\u27 carnival reviewed • Schnoll bridges gap • Faculty survey • The parent as a dropout - are campus riots your fault? • Opinion: A fairy tale • Sleep away • Polemic, Pt. 2 • The women who virtually run UC • Dress regulations • Ursinus in the springtime: a photographic essay • Dr. Ramsay to speak at banquet • Heisinger captures two sprint titles; Bears place third in championships • Netmen massacre LaSalle to clinch winning season • Five athletes are honored • MAC track championship results • 1919 Nittany Lions were the toughest, says President • Softball girls defeat Trenton; Tennis, lacrosse squads win • Studio art unveiled; Bold talent shown • Spring queen, court named; Highlights Parents Day fete • Cub and Key chosen for grades, activities • Chem. students\u27 research noted • Scholar named • Alumni seminar to feature Kerr • I.F. weekend presents Clam • Bill Buckley to speak at UC graduation • Pre-med elections held • Merck presents grant to Ursinus • UC receives first payment for Library • New York Times critic makes appearance at UC • CCC appoints \u2769 advisors • Templeton to head community drive • Push-a-thon • Ruby in preparation, Centennial featuredhttps://digitalcommons.ursinus.edu/weekly/1175/thumbnail.jp

The Freshman, vol. 5, no. 15

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students