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This paper discusses the principles of Islamic Sharia by analyzing the verses of the Qur'an, hadith, and some explanations of the scholars of fiqh. The principles of Islamic Sharia include justice, freedom, shura, humanely, fraternity and solidarity. Islamic civilization built on these principles has existed for several centuries ago in Asia, Africa, and Europe and it contributes greatly to humans and humanity in the form of prosperity, happiness, security, and prosperity to all mankind

WEB-BASED LEARNING MODEL USING HOT POTATOES APPLICATIONS TO INCREASE LANGUAGE STUDENT ACHIEVEMENT

The aim of this research was generally (1) to know the implementation of web-based learning model using hot potatoes application to increase language student achievement (2) to know student interest in web-based learning model by using hot potatoes application to increase language student achievement. This research used quasi experimental method. This research was conducted at second grade students of Junior High School 8 Makassar with 850 students’ population. The writer used a random sampling technique. The total sample used was 60 students. The researcher divides the sample into two classes: the experimental class and the control class. Instruments research used is test, questionnaire and interview. Web-based learning model using hot potatoes application can help students develop their language ability. Web-based learning model using hot potatoes application is very effective to be applied to avoid boredom and boredom of students in following the learning proces

Pengaruh Emulgator Terhadap Aktivitas Antioksidan Krim Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus Sabdariffa Linn)

Proses formulasi sediaan dapat berpengaruh terhadap aktivitas obat, khususnya sediaan yang mengandung antioksidan. Penelitian ini bertujuan untuk mengetahui pengaruh emulgator terhadap aktivitas antioksidan krim ekstrak etanol kelopak bunga rosella (Hibiscus sabdariffa L). Kelopak bunga rosella (Hibiscus sabdariffa L) dimaserasi menggunakan etanol 70%. Ekstrak kemudian dibuat krim konsentrasi 2%, 3% dan 4% dengan variasi kombinasi emulgator Anionik (Asam Stearat dan Trietanolamin) serta emulgator nonionik (Tween 60 dan Span 60). Pengujian aktivitas antioksidan dilakukan dengan mengukur persen penghambatan sediaan terhadap radikal bebas DPPH termasuk setelah penyimpanan. Aktivitas penghambatan radikal bebas DPPH untuk basis dengan emulgator nonionik (2%, 3%, 4%) serta anionik (2%, 3%, 4%) berturut-turut adalah (17,90%, 19,33%, 21,53%) serta (49,01%, 30,76%, 17,69%). Sedangkan untuk sediaan anionik berturut-turut adalah 73,73%; 69,16%; 67,27% (Sebelum penyimpanan) dan 55,88%; 50,16%; 49,00% (Setelah penyimpanan). Untuk krim nonionik berturut-turut adalah 68,57%; 61,87%; 59,30% (Sebelum penyimpanan) dan 42,66%; 47,76%; 48,75% (setelah penyimpanan). Analisis statistik rancangan acak kelompok taraf kepercayaan 5% dan 1% terhadap basis, sediaan dan penyimpanan menghasilkan bahwa jenis dan jumlah emulgator tidak mempengaruhi aktivitas antioksidan sediaan yang mengandung ekstrak kelopak bunga rosella (Hibiscus sabdariffa L) dan aktivitas antioksidan sediaan krim ekstrak kelopak bunga rosella (Hibiscus sabdariffa L) menurun setelah penyimpanan

ENGLISH WISE QUOTES AS MEDIA FOR STUDENTS’ VOCABULARY MASTERY AT SMP NEGERI 35 MAKASSAR

This research focuses on the students' English vocabulary mastery through wise quotes. The purpose of this research was to find out whether with wise quotes, students' vocabulary understanding will increase or not. This research used a pre-experimental research method by giving a pre-test and post-test. The sample of this research is class VIII.7 SMP Negeri 35 Makassar in the academic year 2021/2022, totaling 20 people. This research uses SPSS v.16 which can show the results of the analysis of a significant increase in test scores and can prove the influence of this research. The results of this study indicate that the significance value is 0.000, which is smaller than 0.05, which means that this research has a significant effect. Therefore, it can be concluded that wise quotes have an increasing effect on students' vocabulary comprehension, and it can be seen that through wise quotes, students can become more motivated in the learning process

Local Regulation Review in Realizes Legal Order of the Local Governance

The concept of local autonomy is granted to the people as a whole legal community with authority to regulate and manage the government affairs. Local regulation in its formation both formally and materially should be suitable to the provisions of higher legislation. The type of research is normative and empirical/sociological. Legal resources using primary and secondary data. Data have been obtained from this research were analyzed by using qualitative-descriptive and using theoretical basis and data in its discussion. The results of the research shows that the essence of local regulations review is an action to assess in both formal and material on local regulation by the Supreme Court and the Central Government (Ministry of Domestic Affairs) through the procedures of review that have been determined by the laws and regulations in an effort to ensure the realization of legal order based on justice, legal certainty and utility principles. However, it has not been realized because the dualism of local regulations review that indicates the occurrence of legal disorder in the review of local regulations. Keywords: Executive Review, Judicial Review, Local Autonomy, Local Regulatio

Relationship Marketing Mix (Marketing Mix) in Patients with Trip Unit Outpatient Rsia Pertiwi Makassar Year 2011

Decreased patients visit in RSIA Pertiwi Makassar closely related to the health care provided hospitals and how hospitals serving patients. Thus, the hospital managers should consider the seven elements of the marketing mix are product, price, place, promotion, people, physical evidence and the process. This is the earliest stimulus affects consumer behavior before going through various stages or processes until eventually decided to recover some hospital services. This research aims to determine the relationship between marketing mix and patients visit in RSIA Pertiwi Makassar. This type of research was quantitative research with used survey form by using cross sectional approach. To obtain data in the field conducted by distributing questionnaires to 98 respondents who currently check their health in an outpatient unit. Based on research results indicate that there is a relationship between the product (product and services), place (location service), promotion (promotional marketing communications) and people (health workers), physical evidence (physical appearance) and process (process/service procedures) to visit patients in RSIA Pertiwi Makassar. This study suggests to the RSIA Pertiwi Makassar should do marketing mix elements. in terms of products, although still not complete but the amount that needed to be added. There should be other promotions such as direct promotion of the hospital staff or through print media (newspapers), television advertising. In terms of physical facilities, need to pay attention to the condition of cleanliness of the room and WC patient hospitalization. Service process there needs to be discipline and promptness of service and the firmness of the hospital management to health professionals serving

Global Retinoblastoma Presentation and Analysis by National Income Level.

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs

The global retinoblastoma outcome study : a prospective, cluster-based analysis of 4064 patients from 149 countries

DATA SHARING : The study data will become available online once all analyses are complete.BACKGROUND : Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. METHODS : We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1, 2017, and Dec 31, 2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. FINDINGS : The cohort included 4064 children from 149 countries. The median age at diagnosis was 23·2 months (IQR 11·0–36·5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0·8%) of 636 children from high-income countries, 55 (5·4%) of 1027 children from upper-middle-income countries, 342 (19·7%) of 1738 children from lower-middle-income countries, and 196 (42·9%) of 457 children from low-income countries. Enucleation surgery was available for all children and intravenous chemotherapy was available for 4014 (98·8%) of 4064 children. The 3-year survival rate was 99·5% (95% CI 98·8–100·0) for children from high-income countries, 91·2% (89·5–93·0) for children from upper-middle-income countries, 80·3% (78·3–82·3) for children from lower-middle-income countries, and 57·3% (52·1-63·0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16·67; 95% CI 4·76–50·00), cT4 advanced tumour compared to cT1 (8·98; 4·44–18·18), and older age at diagnosis in children up to 3 years (1·38 per year; 1·23–1·56). For children aged 3–7 years, the mortality risk decreased slightly (p=0·0104 for the change in slope). INTERPRETATION : This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.The Queen Elizabeth Diamond Jubilee Trust and the Wellcome Trust.https://www.thelancet.com/journals/langlo/homeam2023Paediatrics and Child Healt