Knowledge for a warmer world: A patent analysis of climate change adaptation technologies

YesTechnologies can help strengthen the resilience of our economy against existential climate-risks. We investigate climate change adaptation technologies (CCATs) in US patents to understand (1) historical patterns and possible drivers of innovation; (2) scientific and technological requirements to develop and use CCATs; and (3) CCATs’ potential technological synergies with mitigation. First, in contrast to mitigation, innovation in CCATs only slowly takes off, indicating a relatively low awareness of investors for solutions to cope with climate risks. We discuss how historical trends in environmental regulation, energy prices, and public support may have contributed to patenting in CCATs. Second, CCATs form two main clusters: science-intensive ones in agriculture, health, and monitoring technologies; and engineering-intensive ones in coastal, water, and infrastructure technologies. Analyses of technology-specific scientific and technological knowledge bases inform directions for how to facilitate advancement, transfer and use of CCATs. Lastly, CCATs show strong technological complementarities with mitigation as more than 25% of CCATs bear mitigation benefits. While not judging about the complementarity of mitigation and adaptation in general, our results suggest how policymakers can harness these technological synergies to achieve both goals simultaneously

A Review of Agent-Based Modeling of Climate-Energy Policy

Agent-based models (ABMs) have recently seen much application to the field of climate mitigation policies. They offer a more realistic description of micro behavior than traditional climate policy models by allowing for agent heterogeneity, bounded rationality and nonmarket interactions over social networks. This enables the analysis of a broader spectrum of policies. Here, we review 61 ABM studies addressing climate-energy policy aimed at emissions reduction, product and technology diffusion, and energy conservation. This covers a broad set of instruments of climate policy, ranging from carbon taxation, and emissions trading through adoption subsidies to information provision tools such as smart meters and eco-labels. Our treatment pays specific attention to behavioral assumptions and the structure of social networks. We offer suggestions for future research with ABMs to answer neglected policy questions. This article is categorized under: Climate Economics > Economics of Mitigation. © 2020 Wiley Periodicals, Inc.This study has received funding through an ERC Advanced Grant from the European Research Council (ERC) under the European Union's Horizon 2020 Research and Innovation Programme (grant agreement no. 741087). I.S. acknowledges financial support from the Russian Science Foundation [RSF grant number 19-18-00262]

Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens

In three-dimensional light microscopy, the heterogeneity of the optical density in a specimen ultimately limits the achievable penetration depth and hence the three-dimensional resolution. The most direct approach to reduce aberrations, improve the contrast and achieve an optimal resolution is to minimise the impact of changes of the refractive index along an optical path. Many implementations of light sheet fluorescence microscopy operate with a large chamber filled with an aqueous immersion medium and a further inner container with the specimen embedded in a possibly entirely different non-aqueous medium. In order to minimise the impact of the latter on the optical quality of the images, we use multi-facetted cuvettes fabricated from vacuum-formed ultra-thin fluorocarbon (FEP) foils. The ultra-thin FEP-foil cuvettes have a wall thickness of about 10–12 µm. They are impermeable to liquids, but not to gases, inert, durable, mechanically stable and flexible. Importantly, the usually fragile specimen can remain in the same cuvette from seeding to fixation, clearing and observation, without the need to remove or remount it during any of these steps. We confirm the improved imaging performance of ultra-thin FEP-foil cuvettes with excellent quality images of whole organs such us mouse oocytes, of thick tissue sections from mouse brain and kidney as well as of dense pancreas and liver organoid clusters. Our ultra-thin FEP-foil cuvettes outperform many other sample-mounting techniques in terms of a full separation of the specimen from the immersion medium, compatibility with aqueous and organic clearing media, quick specimen mounting without hydrogel embedding and their applicability for multiple-view imaging and automated image segmentation. Addit

Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens

In three-dimensional light microscopy, the heterogeneity of the optical density in a specimen ultimately limits the achievable penetration depth and hence the three-dimensional resolution. The most direct approach to reduce aberrations, improve the contrast and achieve an optimal resolution is to minimise the impact of changes of the refractive index along an optical path. Many implementations of light sheet fluorescence microscopy operate with a large chamber filled with an aqueous immersion medium and a further inner container with the specimen embedded in a possibly entirely different non-aqueous medium. In order to minimise the impact of the latter on the optical quality of the images, we use multi-facetted cuvettes fabricated from vacuum-formed ultra-thin fluorocarbon (FEP) foils. The ultra-thin FEP-foil cuvettes have a wall thickness of about 10–12 µm. They are impermeable to liquids, but not to gases, inert, durable, mechanically stable and flexible. Importantly, the usually fragile specimen can remain in the same cuvette from seeding to fixation, clearing and observation, without the need to remove or remount it during any of these steps. We confirm the improved imaging performance of ultra-thin FEP-foil cuvettes with excellent quality images of whole organs such us mouse oocytes, of thick tissue sections from mouse brain and kidney as well as of dense pancreas and liver organoid clusters. Our ultra-thin FEP-foil cuvettes outperform many other sample-mounting techniques in terms of a full separation of the specimen from the immersion medium, compatibility with aqueous and organic clearing media, quick specimen mounting without hydrogel embedding and their applicability for multiple-view imaging and automated image segmentation. Addit

Skill transferability and the stability of transition pathways - a learning-based explanation for patterns of diffusion

Understanding and governing technology transitions is essential to cope with major challenges of the 21st century such as climate change or digitization. In this paper, a learning-based approach is developed to explain the dynamics of different transition pathways. Technological know-how is necessary to make effective use of new machinery and capital goods. Firms and employees accumulate technology-specific knowledge when working with specific machinery. Radical innovation differs by technology type and pre-existing knowledge may be imperfectly transferable across types. This paper addresses the implications of cross-technology transferability of skills for firm-level technology adoption and its consequences for the direction of macro-level technological change. A microeconomically founded model of technological learning is introduced. The model is based on empirical and theoretical insights from the innovation literature. In a simulation study using the macroeconomic ABM Eurace@unibi-eco and applied to the context of green technology diffusion, it is shown that a high transferability of knowledge has ambiguous effects. It accelerates the diffusion process initially but comes at the cost of long-term technological stability and specialization. For firms, it is easy to adopt new technology, but also easy to switch back to the incumbent type. Technological instability can be macroeconomically costly

The economics of transition pathways: a proposed taxonomy and a policy experiment

Pathways of transition differ across countries, industrial sectors, firms and technologies, but little is known about the reasons for these differences and macroeconomic consequences. I show theoretically how differences in transition patterns and macroeconomic side effects can be explained by the characteristics of competing technologies. Competing technologies are characterized by their relative superiority in an exogenous socio-technical landscape, their relative maturity and cross-technology interactions in the process of specialization. These characteristics are linked to the multi-layer perspective of transition theory and build the conceptual basis of technology in the macroeconomic agent-based model Eurace@unibi-eco. It is shown that the characteristics can be an explanation for heterogeneous transition pathways. Policy may alter the exogenous landscape conditions that surround technological competition. It is shown how different market-based instruments can be used to accelerate and stabilize a transition process. Taxes and subsidies perform differently conditional on the characteristics of competing technologies

The rise of science in low-carbon energy technologies

Successfully combating climate change will require substantial technological improvements in Low-Carbon Energy Technologies (LCETs), but designing efficient allocation of R&D budgets requires a better understanding of how LCETs rely on scientific knowledge. Using data covering almost all US patents and scientific articles that are cited by them over the past two centuries, we describe the evolution of knowledge bases of ten key LCETs and show how technological interdependencies have changed over time. The composition of low-carbon energy innovations shifted over time, from Hydro and Wind energy in the 19th and early 20th century, to Nuclear fission after World War II, and more recently to Solar PV and back to Wind. In recent years, Solar PV, Nuclear fusion and Biofuels (including energy from waste) have 35–65% of their citations directed toward scientific papers, while this ratio is less than 10% for Wind, Solar thermal, Hydro, Geothermal, and Nuclear fission. Over time, the share of patents citing science and the share of citations that are to scientific papers has been increasing for all technology types. The analysis of the scientific knowledge base of each LCET reveals three fairly separate clusters, with nuclear energy technologies, Biofuels and Waste, and all the other LCETs. Our detailed description of knowledge requirements for each LCET helps to design of targeted innovation policies

Die Macht der dunklen Seite : die Chancen der Lichtscheiben-Fluoreszenzmikroskopie in der modernen Zell- und Entwicklungsbiologie

"Mehr Licht!" – so lauteten, glaubt man seinem Arzt Carl Vogel, die letzten Worte des größten deutschen Dichters und Denkers Johann Wolfgang Goethe. Aus der Sicht der Fluoreszenzmikroskopie ist das kein guter Grundsatz. Die Kernidee der Lichtscheiben-Fluoreszenzmikroskopie (LSFM) liegt in der Macht der dunklen Seite. Anders gesagt: Sie folgt dem Prinzip, dass weniger manchmal viel mehr sein kann. Die schonende Beleuchtung empfindlicher Proben bei der LSFM birgt großes Potenzial für die moderne Zell- und Entwicklungsbiologie