Anosov representations and proper actions

We establish several characterizations of Anosov representations of word hyperbolic groups into real reductive Lie groups, in terms of a Cartan projection or Lyapunov projection of the Lie group. Using a properness criterion of Benoist and Kobayashi, we derive applications to proper actions on homogeneous spaces of reductive groups.Comment: 73 pages, 4 figures; to appear in Geometry & Topolog

Pest risk analysis for Bactrocera invadens : Guidelines on Pest Risk Analysis

Stripping related moisture damage has been recognized as one of the major pavement distresses since the early 1990s. The main objective of this study is to establish an effective test protocol to quantify moisture susceptibility of asphalt pavements. To this end, selective test methods (Texas Boiling test, Tensile Strength Ratio, Retained Stability, and Hamburg Wheel Test), and procedures based on surface chemistries and molecular-level mechanistic properties have been investigated in this study. Firstly, a comprehensive list of literature related to moisture damage in asphalts was reviewed. Based on the literature review, a detailed project plan and test matrix were developed. Binder samples originated from two different crude sources were collected. The moisture resistance related tests such as static contact angle measurements and Texas Boiling tests were conducted. Besides, asphalt binders’ nanomechanical properties using an Atomic Force Microscopy (AFM) and surface chemistries using a static contact were evaluated in the laboratory. Based on limited test data and analysis, it is concluded that there does not exist any single test method that all agencies are comfortable and equipped to follow in their daily work as each technique has some merits and demerits. However, the Texas Boiling test is found to be the simplest method that requires minimal time and resources. On the other hand, surface chemistry and atomic force microscope-based techniques are becoming popular among researchers and pavement professionals. Findings of this study are expected to help ARDOT in selecting an appropriate moisture resistance test method that is simple, reliable, and easy to implement in their routine work

La mer d’Aral reviendra-t-elle ?

Au mois de septembre 2001, un véhicule kaki parcourait les routes et les pistes entre Tachkent, Noukous, Mojnaq et le fond asséché de la mer d’Aral. Il s’arrêtait souvent en des lieux insolites : ses cinq passagers et le chauffeur descendaient munis d’accessoires tels que marteaux, spatules, couteaux, petites bouteilles en plastique, conductimètre pour mesurer des propriétés de l’eau. Ils étudiaient et prélevaient les roches, l’eau des rivières ou des captages de la nappe phréatique. De temps..

Ciliary Beating Recovery in Deficient Human Airway Epithelial Cells after Lentivirus Ex Vivo Gene Therapy

Primary Ciliary Dyskinesia is a heterogeneous genetic disease that is characterized by cilia dysfunction of the epithelial cells lining the respiratory tracts, resulting in recurrent respiratory tract infections. Despite lifelong physiological therapy and antibiotics, the lungs of affected patients are progressively destroyed, leading to respiratory insufficiency. Recessive mutations in Dynein Axonemal Intermediate chain type 1 (DNAI1) gene have been described in 10% of cases of Primary Ciliary Dyskinesia. Our goal was to restore normal ciliary beating in DNAI1–deficient human airway epithelial cells. A lentiviral vector based on Simian Immunodeficiency Virus pseudotyped with Vesicular Stomatitis Virus Glycoprotein was used to transduce cultured human airway epithelial cells with a cDNA of DNAI1 driven by the Elongation Factor 1 promoter. Transcription and translation of the transduced gene were tested by RT–PCR and western blot, respectively. Human airway epithelial cells that were DNAI1–deficient due to compound heterozygous mutations, and consequently had immotile cilia and no outer dynein arm, were transduced by the lentivirus. Cilia beating was recorded and electron microscopy of the cilia was performed. Transcription and translation of the transduced DNAI1 gene were detected in human cells treated with the lentivirus. In addition, immotile cilia recovered a normal beat and outer dynein arms reappeared. We demonstrated that it is possible to obtain a normalization of ciliary beat frequency of deficient human airway epithelial cells by using a lentivirus to transduce cells with the therapeutic gene. This preliminary step constitutes a conceptual proof that is indispensable in the perspective of Primary Ciliary Dyskinesia's in vivo gene therapy. This is the first time that recovery of cilia beating is demonstrated in this disease

António Reis (coord. par), Portugal. 20 anos de democracia

Guichard Francois. António Reis (coord. par), Portugal. 20 anos de democracia. In: Lusotopie, n°3, 1996. L'oppression paternaliste au Brésil. pp. 409-410