56 research outputs found
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Kinetic theory of plasma adiabatic major radius compression in tokamaks
A kinetic approach is developed to understand the individual charged particle behavior as well as plasma macro parameters (temperature, density, etc.) during the adiabatic R-compression in a tokamak. The perpendicular electric field from Ohm`s law at zero resistivity E = {minus}v{sub E} x B/c is made use of to obtain the equation for particle velocity evolution in order to describe the particle motion during the R-compression. Expressions for both passing and trapped particle energy and pitch angle change are obtained for a plasma with high aspect ratio and circular magnetic surfaces. The particle behavior near the trapped passing boundary during the compression is also studied to understand the shift induced loss of alpha particles produced by D-T fusion reactions in Tokamak Fusion Test Reactor experiments. Qualitative agreement is obtained with the experiments. Solving the drift kinetic equation in the collisional case, i.e., when the collisional frequency {nu}{sub coll} of given species exceeds the inverse compression time {tau}{sub compr}{sup {minus}1}, the authors obtain that the temperature and the density evolution is reduced to the MHD results T {approximately} R{sup {minus}4/3} and n {approximately} R{sup {minus}2}, respectively. In the opposite case, {nu}{sub coll} {much_lt} {tau}{sub compr}{sup {minus}1}, the longitudinal component of the temperature evolve like R(superscript)-2(end superscript) and perpendicular components of the temperature evolve like T{sub {parallel}} {approximately} R{sup {minus}2} and T{sub {perpendicular}} {approximately} R{sup {minus}1}. The effect of toroidicity is negligible in both cases
Stochastic Orbit Loss of Neutral Beam Ions From NSTX Due to Toroidal Alfven Eigenmode Avalanches
Short toroidal Alfven eigenmode (TAE) avalanche bursts in the National Spherical Torus Experiment (NSTX) cause a drop in the neutron rate and sometimes a loss of neutral beam ions at or near the full injection energy over an extended range of pitch angles. The simultaneous loss of wide ranges of pitch angle suggests stochastic transport of the beam ions occurs. When beam ion orbits are followed with a guiding center code that incorporates plasma's magnetic equilibrium plus the measured modes, the predicted ranges of lost pitch angle are similar to those seen in the experiment, with distinct populations of trapped and passing orbits lost. These correspond to domains where the stochasticity extends in the orbit phase space from the region of beam ion deposition to the loss boundary
Regulation of DJ-1 by glutaredoxin 1 \u3ci\u3ein vivo – implications for Parkinson’s disease\u3c/i\u3e
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the substantia nigra. Mutations in PARK7 (DJ-1) result in early onset autosomal recessive PD, and oxidative modification of DJ-1 has been reported to regulate the protective activity of DJ-1 in vitro. Glutathionylation is a prevalent redox modification of proteins resulting from the disulfide adduction of the glutathione moiety to a reactive cysteine-SH; and glutathionylation of specific proteins has been implicated in regulation of cell viability. Glutaredoxin 1 (Grx1) is the principal deglutathionylating enzyme within cells, and it has been reported to mediate protection of dopaminergic neurons in C. elegans, however many of the functional downstream targets of Grx1 in vivo remain unknown. Previously, DJ-1 protein content was shown to decrease concomitantly with diminution of Grx1 protein content in cell culture of model neurons (SH-SY5Y and Neuro-2A lines). In the current study we aimed to investigate the regulation of DJ-1 by Grx1 in vivo and characterize its glutathionylation in vitro. Here, with Grx−/− mice we provide evidence that Grx1 regulates protein levels of DJ-1 in vivo. Furthermore, with model neuronal cells (SH-SY5Y) we observed decreased DJ-1 protein content in response to treatment with known glutathionylating agents; and with isolated DJ-1 we identified two distinct sites of glutathionylation. Finally, we found that overexpression of DJ-1 in the dopaminergic neurons partly compensates for the loss of the Grx1 homolog in a C. elegans in vivo model of PD. Therefore; our results reveal a novel redox modification of DJ-1 and suggest a novel regulatory mechanism for DJ-1 content in vivo
Energetic ion transport by microturbulence is insignificant in tokamaks
Energetic ion transport due to microturbulence is investigated in magnetohydrodynamic-quiescent plasmas by way of neutral beam injection in the DIII-D tokamak [J. L. Luxon, Nucl. Fusion 42, 614 (2002)]. A range of on-axis and off-axis beam injection scenarios are employed to vary relevant parameters such as the character of the background microturbulence and the value of Eb/Te , where Eb is the energetic ion energy and Te the electron temperature. In all cases, it is found that any transport enhancement due to microturbulence is too small to observe experimentally. These transport effects are modeled using numerical and analytic expectations that calculate the energetic ion diffusivity due to microturbulence. It is determined that energetic ion transport due to coherent fluctuations (e.g., Alfvén eigenmodes) is a considerably larger effect and should therefore be considered more important for ITER.United States. Dept. of Energy (DE-FC02-04ER54698)United States. Dept. of Energy (DE-FC02-99ER54512)United States. Dept. of Energy (DE-FG03-97ER54415)United States. Dept. of Energy (DE-FG02-07ER54917)United States. Dept. of Energy (DE-AC02-09CH11466)United States. Dept. of Energy (SC-G903402)United States. Dept. of Energy (DE-FG02-08ER54984)United States. Dept. of Energy ( DE-AC52-07NA27344)United States. Dept. of Energy ( DE-FG02-89ER53296)United States. Dept. of Energy (DE-FG02-08ER54999)United States. Dept. of Energy (DE-AC05-00OR22725
Fast Ion Effects During Test Blanket Module Simulation Experiments in DIII-D
Fast beam-ion losses were studied in DIII-D in the presence of a scaled mockup of two Test Blanket Modules (TBM) for ITER. Heating of the protective tiles on the front of the TBM surface was found when neutral beams were injected and the TBM fields were engaged. The fast-ion core confinement was not significantly affected. Different orbit-following codes predict the formation of a hot spot on the TBM surface arising from beam-ions deposited near the edge of the plasma. The codes are in good agreement with each other on the total power deposited at the hot spot predicting an increase in power with decreasing separation between the plasma edge and the TBM surface. A thermal analysis of the heat flow through the tiles shows that the simulated power can account for the measured tile temperature rise. The thermal analysis, however, is very sensitive to the details of the localization of the hot spot which is predicted to be different among the various codes
Computation of Alfvèn eigenmode stability and saturation through a reduced fast ion transport model in the TRANSP tokamak transport code
Alfvénic instabilities (AEs) are well known as a potential cause of enhanced fast ion transport in fusion devices. Given a specific plasma scenario, quantitative predictions of (i) expected unstable AE spectrum and (ii) resulting fast ion transport are required to prevent or mitigate the AE- induced degradation in fusion performance. Reduced models are becoming an attractive tool to analyze existing scenarios as well as for scenario prediction in time-dependent simulations. In this work, a neutral beam heated NSTX discharge is used as reference to illustrate the potential of a reduced fast ion transport model, known as kick model, that has been recently implemented for interpretive and predictive analysis within the framework of the time-dependent tokamak transport code TRANSP. Predictive capabilities for AE stability and saturation amplitude are first assessed, based on given thermal plasma profiles only. Predictions are then compared to experimental results, and the interpretive capabilities of the model further discussed. Overall, the reduced model captures the main properties of the instabilities and associated effects on the fast ion population. Additional information from the actual experiment enables further tuning of the model’s parameters to achieve a close match with measurements.readme, data file
Phase space effects on fast ion distribution function modeling in tokamaks
Integrated simulations of tokamak discharges typically rely on classical physics to model energetic particle (EP) dynamics. However, there are numerous cases in which energetic particles can suffer additional transport that is not classical in nature. Examples include transport by applied 3D magnetic perturbations and, more notably, by plasma instabilities. Focusing on the effects of instabilities, ad-hoc models can empirically reproduce increased transport, but the choice of transport coefficients is usually somehow arbitrary. New approaches based on physics-based reduced models are being developed to address those issues in a simplified way, while retaining a more correct treatment of resonant wave-particle interactions. The kick model implemented in the tokamak transport code TRANSP is an example of such reduced models. It includes modifications of the EP distribution by instabilities in real and velocity space, retaining correlations between transport in energy and space typical of resonant EP transport. The relevance of EP phase space modifications by instabilities is first discussed in terms of predicted fast ion distribution. Results are compared with those from a simple, ad-hoc diffusive model. It is then shown that the phase-space resolved model can also provide additional insight into important issues such as internal consistency of the simulations and mode stability through the analysis of the power exchanged between energetic particles and the instabilities.readme, data file
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Magnetosonic Eigenmodes Near the Magnetic Field Well in a Spherical Torus
The structure and spectrum of magnetosonic Alfven eigenmodes in spherical torus in the presence of magnetic field well are studied. Analytical solution for eigenmodes localized in the well is obtained and compared with the numerical one. The possibility of using the eigenmode spectrum measurements for reconstructing the magnetic field well, and, thus, central magnetic safety factor profile is discussed
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