EFFECTS OF FATHER ABSENCE ON AGE OF SEXUAL ACTIVITY AND CURRENT STRESS AND ATTACHMENT LEVELS OF YOUNG ADULT WOMEN

This study bridges the gap in literature about the impact of father absence on female adult attachment and current stress levels. A sample of 666 female college students between the ages of 18 and 22 at the University of Kentucky was recruited to complete an online survey about their experience with their fathers and the effects on their attachment and stress levels, while assessing the age of their first sexual experience. Father absence seems to be a significant predictor of earlier sexual activity among females and anxious attachment styles, along with higher stress levels. When the father is absent from the home, females have sex earlier than when the father is present in the home. Females who experience father absence have higher anxious attachment levels and higher current stress levels. These findings inform therapists about the importance of recognizing attachment injuries when dealing with individuals and supports the need for mother and father involvement in a female’s life

Kinematics of Circumgalactic Gas: Feeding Galaxies and Feedback

We present observations of 50 pairs of redshift z ~ 0.2 star-forming galaxies and background quasars. These sightlines probe the circumgalactic medium (CGM) out to half the virial radius, and we describe the circumgalactic gas kinematics relative to the reference frame defined by the galactic disks. We detect halo gas in MgII absorption, measure the equivalent-width-weighted Doppler shifts relative to each galaxy, and find that the CGM has a component of angular momentum that is aligned with the galactic disk. No net counter-rotation of the CGM is detected within 45 degrees of the major axis at any impact parameter. The velocity offset of the circumgalactic gas correlates with the projected rotation speed in the disk plane out to disk radii of roughly 70 kpc. We confirm previous claims that the MgII absorption becomes stronger near the galactic minor axis and show that the equivalent width correlates with the velocity range of the absorption. We cannot directly measure the location of any absorber along the sightline, but we explore the hypothesis that individual velocity components can be associated with gas orbiting in the disk plane or flowing radially outward in a conical outflow. We conclude that centrifugal forces partially support the low-ionization gas and galactic outflows kinematically disturb the CGM producing excess absorption. Our results firmly rule out schema for the inner CGM that lack rotation and suggest that angular momentum as well as galactic winds should be included in any viable model for the low-redshift CGM.Comment: Accepted for publication in the Astrophysical Journa

Monitoring of outpatient parenteral antimicrobial therapy (OPAT) and implementation of clinical pharmacy services at a community hospital infusion unit

Background: In 2004, the Infectious Diseases Society of America (IDSA) published monitoring guidelines for outpatient parenteral antimicrobial therapy (OPAT), but no assessment of their utilization has been reported. We evaluated adherence to these recommendations by physicians at infusion centers and then piloted a program of supervision of monitoring by pharmacists. Methods: Phase I: We performed a retrospective case-control study of patients who received OPAT over one year at two hospital infusion centers. Controls were patients treated by an infectious diseases (ID) physician, and cases were those without an ID physician. Patients were excluded if they received fewer than 3 days of OPAT. Clinical pharmacy monitoring services were then implemented for patients on OPAT prescribed by non-ID physicians at one hospital’s infusion unit. Two outcomes were measured: adherence to guidelines on monitoring, and attainment of goal vancomycin and aminoglycoside serum concentrations when appropriate. The results for non-ID physicians were compared to both ID physicians and subsequently a pharmacist. Results: Ninety nine patients were included in the retrospective study. Compared with patients who had ID physician supervision, the non-ID physicians who prescribed OPAT for 39 patients had lower adherence to monitoring recommendations (35.9% vs.68.3%, p=0.003). No difference could be detected in achievement of goal vancomycin and aminoglycoside serum concentrations for the 14 cases and 19 controls requiring therapeutic drug monitoring (57.1% vs. 68.4% respectively, p=0.765). Seven patients were enrolled in the study after pharmacy monitoring was implemented. Adherence to monitoring recommendations for these patients was significantly improved compared to the prior patients that lacked ID physician supervision (35.9% vs. 100%, p=0.0065)

Approaches of Digital Pedagogies for the Appreciation and Preservation of Local Trans and Multilingual Cultural Heritages

In an effort to provide culturally and linguistically relevant Spanish as a Heritage Language (SHL) programs in the United States, several language programs have turned to creating digital language learning and teaching materials using various data sources, digital tools, methodologies, cultural practices, digital humanities platforms and projects, as well as Open Educational Resources (OER). This facilitates innovative knowledge production that preserves local translingual and multilingual cultural heritages and identities of Spanish HLLs from multiracial backgrounds in the US in analog and online spaces. Current initiatives in multilingual, decolonial, postcolonial Digital Humanities (DH) are pushing back against the aporias in the digital age through ethical production and representation of subjects, cultures, languages and stories that have been othered, marginalized, excluded or misrepresented (Risam, 2019: 141). Furthermore, SHL sociolinguists encourage the development of critical language and cultural awareness among Spanish HLL student populations. This approach allows students to “develop a consciousness of the political, social, and economic power structures that underlie language use and the distribution of the so-called prestige and non-prestigious varieties” and “validate(s) and express(es) the diversity of students’ cultures, including US-based heritage cultures” (Beaudrie & Wilson, 2022: 67). With this in mind, in this panel, experts in the fields of SHL, DH and OER will present an OER for introductory SHL classes that connects learning and teaching materials using digital technologies and tools while also centering personal, local, and regional cultural community knowledge of South Texas to encourage production of their own stories and resources in the digital cultural record and an appreciation and preservation of their trans and multilingual identities and cultural heritages. Additionally, this panel will discuss the steps being taken by the R1 HSI university funding the development of this OER to infuse open pedagogy principles across disciplines in order to cultivate deeper student engagement

Low Mass Group Environments have no Substantial Impact on the Circumgalactic Medium Metallicity

We explore how environment affects the metallicity of the circumgalactic medium (CGM) using 13 low mass galaxy groups (2-5 galaxies) at $\langle z_{abs}\rangle=0.25$ identified near background quasars. Using quasar spectra from HST/COS and from Keck/HIRES or VLT/UVES we measure column densities of, or determine limits on, CGM absorption lines. We use a Markov chain Monte Carlo approach with Cloudy to estimate metallicities of cool ($T\sim10^4$K) CGM gas within groups and compare them to CGM metallicities of 47 isolated galaxies. Both group and isolated CGM metallicities span a wide range ($-2<$[Si/H]$<0$), where the mean group ($-0.54\pm0.22$) and isolated ($-0.77\pm0.14$) CGM metallicities are similar. Group and isolated environments have similar distributions of {\HI} column densities as a function of impact parameter. However, contrary to isolated galaxies, we do not find an anti-correlation between {\HI} column density and the nearest group galaxy impact parameter. We additionally divided the groups by member luminosity ratios (i.e., galaxy-galaxy and galaxy-dwarf groups). While there was no significant difference in their mean metallicities, a modest increase in sample size should allow one to statistically identify a higher CGM metallicity in galaxy-dwarf groups compared to galaxy-galaxy groups. We conclude that either environmental effects have not played an important role in the metallicity of the CGM at this stage and expect that this may only occur when galaxies are strongly interacting or merging, or that some isolated galaxies have higher CGM metallicities due to past interactions. Thus, environment does not seem to be the cause of the CGM metallicity bimodality.Comment: 14 pages, 5 figures, 2 figure sets, 1 machine-readable tabl

A Naturally-Occurring Histone Acetyltransferase Inhibitor Derived from Garcinia indica Impairs Newly Acquired and Reactivated Fear Memories

The study of the cellular and molecular mechanisms underlying the consolidation and reconsolidation of traumatic fear memories has progressed rapidly in recent years, yet few compounds have emerged that are readily useful in a clinical setting for the treatment of anxiety disorders such as post-traumatic stress disorder (PTSD). Here, we use a combination of biochemical, behavioral, and neurophysiological methods to systematically investigate the ability of garcinol, a naturallyoccurring histone acetyltransferase (HAT) inhibitor derived from the rind of the fruit of the Kokum tree (Garcina indica), to disrupt the consolidation and reconsolidation of Pavlovian fear conditioning, a widely studied rodent model of PTSD. We show that local infusion of garcinol into the rat lateral amygdala (LA) impairs the training and retrieval-related acetylation of histone H3 in the LA. Further, we show that either intra-LA or systemic administration of garcinol within a narrow window after either fear conditioning or fear memory retrieval significantly impairs the consolidation and reconsolidation of a Pavlovian fear memory and associated neural plasticity in the LA. Our findings suggest that a naturally-occurring compound derived from the diet that regulates chromatin function may be useful in the treatment of newly acquired or recently reactivated traumatic memories

Anachronistic Grain Growth and Global Structure of the Protoplanetary Disk Associated with the Mature Classical T Tauri Star, PDS 66

We present ATCA interferometric observations of the old (13 Myr), nearby (86pc) classical T Tauri star, PDS 66. Unresolved 3 and 12 mm continuum emission is detected towards PDS 66, and upper limits are derived for the 3 and 6 cm flux densities. The mm-wave data show a spectral slope flatter than that expected for ISM-sized dust particles, which is evidence of grain growth. We also present HST/NICMOS 1.1 micron PSF-subtracted coronagraphic imaging of PDS 66. The HST observations reveal a bilaterally symmetric circumstellar region of dust scattering about 0.32% of the central starlight, declining radially in surface brightness. The light-scattering disk of material is inclined 32 degrees from face-on, and extends to a radius of 170 AU. These data are combined with published optical and longer wavelength observations to make qualitative comparisons between the median Taurus and PDS 66 spectral energy distributions (SEDs). By comparing the near-infrared emission to a simple model, we determine that the location of the inner disk radius is consistent with the dust sublimation radius (1400 K at 0.1 AU). We place constraints on the total disk mass using a flat-disk model and find that it is probably too low to form gas giant planets according to current models. Despite the fact that PDS 66 is much older than a typical classical T Tauri star (< 5 Myr), its physical properties are not much different.Comment: 31 pages, 7 figure

Discovering and Developing Diverse STEM Talent: Enabling Academically Talented Urban Youth to Flourish

The Growing Excellence Gap in K-12 Education, Plucker, Burroughs, and Song (2010) provided compelling evidence that the presence of an excellence gap is demonstrated on both national and state assessments of student performance, with economically disadvantaged, English Language Learners, and historically underprivileged minorities representing a smaller proportion of students scoring at the highest levels of achievement (p. 28). Three case stories of students from IMSA illuminate some of the (a) challenges and opportunities inherent in igniting STEM talent in urban youth and ensuring their success; (b) principles for designing and creating learning experiences and environments that ignite and nurture the development of creative, ethical scientific minds (IMSA, 2009); and (c) institutional lessons that have become clear to us after more than two decades of developing diverse STEM talent

The NCRM wayfinder guide to in-situ methodologies in a Covid-impacted uncertain world

In-situ methodologies are broadly described as multi-sensory qualitative approaches immersed in place and time. Unsurprisingly, the Covid-19 pandemic has dramatically impacted how, and even if, in-situ research can be conducted. Despite constraints, we argue that such methodologies are needed now more than ever because of their utility in understanding inequities in health and place. In this guide, we present a set of reflective questions to guide adaptation of in-situ methodologies for research conducted during the global pandemic and beyond, and provide a working example of how we adapted go-along interviews in practice

The Relation Between Galaxy ISM and Circumgalactic OVI Gas Kinematics Derived from Observations and Λ\LambdaCDM Simulations

We present the first galaxy-OVI absorption kinematic study for 20 absorption systems (EW>0.1~{\AA}) associated with isolated galaxies (0.15$<z<$0.55) that have accurate redshifts and rotation curves obtained using Keck/ESI. Our sample is split into two azimuthal angle bins: major axis ($\Phi<25^{\circ}$) and minor axis ($\Phi>33^{\circ}$). OVI absorption along the galaxy major axis is not correlated with galaxy rotation kinematics, with only 1/10 systems that could be explained with rotation/accretion models. This is in contrast to co-rotation commonly observed for MgII absorption. OVI along the minor axis could be modeled by accelerating outflows but only for small opening angles, while the majority of the OVI is decelerating. Along both axes, stacked OVI profiles reside at the galaxy systemic velocity with the absorption kinematics spanning the entire dynamical range of their galaxies. The OVI found in AMR cosmological simulations exists within filaments and in halos of ~50 kpc surrounding galaxies. Simulations show that major axis OVI gas inflows along filaments and decelerates as it approaches the galaxy while increasing in its level of co-rotation. Minor axis outflows in the simulations are effective within 50-75 kpc beyond that they decelerate and fall back onto the galaxy. Although the simulations show clear OVI kinematic signatures they are not directly comparable to observations. When we compare kinematic signatures integrated through the entire simulated galaxy halo we find that these signatures are washed out due to full velocity distribution of OVI throughout the halo. We conclude that OVI alone does not serve as a useful kinematic indicator of gas accretion, outflows or star-formation and likely best probes the halo virial temperature.Comment: 24 pages, 21 figures, 4 tables. Accepted to ApJ on November 14, 201