377 research outputs found
Reflection and Ducting of Gravity Waves Inside the Sun
Internal gravity waves excited by overshoot at the bottom of the convection
zone can be influenced by rotation and by the strong toroidal magnetic field
that is likely to be present in the solar tachocline. Using a simple Cartesian
model, we show how waves with a vertical component of propagation can be
reflected when traveling through a layer containing a horizontal magnetic field
with a strength that varies with depth. This interaction can prevent a portion
of the downward-traveling wave energy flux from reaching the deep solar
interior. If a highly reflecting magnetized layer is located some distance
below the convection zone base, a duct or wave guide can be set up, wherein
vertical propagation is restricted by successive reflections at the upper and
lower boundaries. The presence of both upward- and downward-traveling
disturbances inside the duct leads to the existence of a set of horizontally
propagating modes that have significantly enhanced amplitudes. We point out
that the helical structure of these waves makes them capable of generating an
alpha-effect, and briefly consider the possibility that propagation in a shear
of sufficient strength could lead to instability, the result of wave growth due
to over-reflection.Comment: 23 pages, 5 figures. Accepted for publication in Solar Physic
Understanding multimorbidity requires sign-disease networks and higher-order interactions, a perspective
Four-quadrant total to static characteristics of an axial flow compressor
Paper presented at the 5th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, South Africa, 1-4 July, 2007.An axial flow compressor operating under near-design conditions exhibits rotation, °ow and pressure difference between inlet and outlet and rotation in the expected directions. However, during abnormal operating conditions, some of these properties may reverse in direction. In this paper, the experimentally determined four-quadrant compressor maps for pressure-rise, torque and efficiency for a three-stage, low speed axial flow compressor are presented. Six possible modes of operation were identified and investigated; two compressor-like modes in the first and third quadrants, and
two turbine-like modes and two highly dissipative modes in the second and fourth quadrants. This paper presents total to static pressure and torque coefficient characteristics for operation in all six quadrants, including reverse rotation modes, as
well as efficiency characteristics where appropriate. Results are compared with those of previous researchers for reverse flow, positive rotation operation. The zero-rotation total to static pressure characteristic has been experimentally determined, and found to take the form of an S-shaped curve passing through the second and fourth quadrants, separating the turbine and dissipative modes in both the second and fourth quadrants.cs201
Ethnic differences in respiratory impairment
Objective Spirometric Z scores by lambda-mu-sigma (LMS) rigorously account for age-related changes in lung function. Recently, the Global Lung Function Initiative (GLI) expanded LMS spirometric Z scores to multiple ethnicities. Hence, in aging populations, the GLI provides an opportunity to rigorously evaluate ethnic differences in respiratory impairment, including airflow limitation and restrictive pattern. Methods Using data from the Third National Health and Nutrition Examination Survey, including participants aged 40-80, we evaluated ethnic differences in GLI-defined respiratory impairment, including prevalence and associations with mortality and respiratory symptoms. Results Among 3506 white Americans, 1860 African Americans and 1749 Mexican Americans, the prevalence of airflow limitation was 15.1% (13.9% to 16.4%), 12.4% (10.7% to 14.0%) and 8.2% (6.7% to 9.8%), and restrictive pattern was 5.6% (4.6% to 6.5%), 8.0% 6.9% to 9.0%) and 5.7% (4.5% to 6.9%), respectively. Airflow limitation was associated with mortality in white Americans, African Americans and Mexican Americans - adjusted HR (aHR) 1.66 (1.23 to 2.25), 1.60 (1.09 to 2.36) and 1.80 (1.17 to 2.76), respectively, but associated with respiratory symptoms only in white Americans - adjusted OR (aOR) 2.15 (1.70 to 2.73). Restrictive pattern was associated with mortality but only in white Americans and African Americans - aHR 2.56 (1.84 to 3.55) and 3.23 (2.06 to 5.05), and associated with respiratory symptoms but only in white Americans and Mexican Americans-aOR 2.16 (1.51 to 3.07) and .12 (1.45 to 3.08), respectively. Conclusions In an aging population, we found ethnic differences in GLI-defined respiratory impairment. In particular, African Americans had high rates of respiratory impairment that were associated with mortality but not respiratory symptoms
Оценивание устойчивого развития окружающей среды на субнациональном уровне в Украине
Рассмотрены существующие методы оценивания устойчивого развития окружающей среды (самостоятельные индикаторы, а также их системы и индексы). Предложен индекс устойчивого развития окружающей среды для оценивания взаимоотношений с окружающей средой на уровне регионов Украины, учитывающий национальные приоритеты в экологической политике. По предложенному региональному индексу получены экологические профили и рейтинг областей Украины.Розглянуто існуючі методи оцінювання сталого розвитку довкілля (самостійні індикатори, а також їх системи та індекси). Запропоновано індекс сталого розвитку довкілля для оцінювання взаємовідносин із навколишнім середовищем на рівні регіонів України, який враховує національні пріоритети в екологічній політиці. За запропонованим регіональним індексом отримано екологічні профілі і рейтинг областей України.The existing methods for assessment of the environment sustainable development (independent indicators, their systems and indices) are considered. The environment sustainability index for assessment of relations with the environment at a regional level for Ukraine is proposed, which takes into account the national priorities in ecological policy. Ecological profiles and rating of the Ukrainian regions are obtained according to the proposed regional index
Technology-enhanced learning on campus: insights from EUNIS e-Learning Task Force
In 2010 the EUNIS e-Learning Task Force (ELTF) members collaborated on a review of tools and technologies in use across our member institutions. One of the key features of that paper was the use of technology to give off-campus learners, such as distance learners, those undertaking field studies and learners in the workplace a richly supported learning experience. Building on the success of that collaboration, the ELTF members have turned their attention this year to the use of technology on campus. Whilst technology and distance learning go hand in hand, universities are often slower to take advantage of the possibilities offered by technology to enrich the learning that takes place in our lecture theatres and classrooms. The reasons for this are often cultural as much as financial or technical. Drawing on experience from across the EUNIS member nations we take a look at the types of tools, learning resources and learning activities that are being used to enhance the traditional curriculum, promote deeper learning and bridge the learning that takes place inside and outside the classroom. We look at a range of innovative projects and the benefits they have delivered, ways of overcoming the barriers to technology-enhanced learning on campus and we speculate about the role and function of the campus of the future
Tomato: a crop species amenable to improvement by cellular and molecular methods
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
In view of the current data, the isolation of useful mutants at the cellular level probably will be of limited value in the genetic improvement of tomato. Protoplast fusion may lead to novel combinations of organelle and nuclear DNA (cybrids), whereas this technique also provides a means of introducing genetic information from alien species into tomato. Important developments have come from molecular approaches. Following the construction of an RFLP map, these RFLP markers can be used in tomato to tag quantitative traits bred in from related species. Both RFLP's and transposons are in the process of being used to clone desired genes for which no gene products are known. Cloned genes can be introduced and potentially improve specific properties of tomato especially those controlled by single genes. Recent results suggest that, in principle, phenotypic mutants can be created for cloned and characterized genes and will prove their value in further improving the cultivated tomato.
Sumoylation and proteasomal activity determine the transactivation properties of the mineralocorticoid receptor
Avaliação de procedimentos de comparações múltiplas em trabalhos publicados na revista Horticultura Brasileira de 1.983 a 2.000
Improving Genetic Prediction by Leveraging Genetic Correlations Among Human Diseases and Traits
Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for most traits. Here theory and simulation study are used to demonstrate that widespread pleiotropy among phenotypes can be utilised to improve genomic risk prediction. We show how a genetic predictor can be created as a weighted index that combines published genome-wide association study (GWAS) summary statistics across many different traits. We apply this framework to predict risk of schizophrenia and bipolar disorder in the Psychiatric Genomics consortium data, finding substantial heterogeneity in prediction accuracy increases across cohorts. For six additional phenotypes in the UK Biobank data, we find increases in prediction accuracy ranging from 0.7 for height to 47 for type 2 diabetes, when using a multi-trait predictor that combines published summary statistics from multiple traits, as compared to a predictor based only on one trait. © 2018 The Author(s)
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