3,550 research outputs found

    Reorganizing in the Wake of Mission Prod. Holdings v. Tempnology: How to Address the Trademark and Bankruptcy Law Issues Created by the Supreme Courtā€™s Recent Decision

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    Bankruptcy law seeks to provide a ā€œfresh startā€ for debtors and an equitable distribution of funds to creditors. Trademark law, on the other hand, aims to ensure proper source identification and protect the public from deception. These policies converge when a trademark owner or licensor has licensed use of the mark to others and hopes to reject this licensing agreement in bankruptcy. Prior to the Supreme Courtā€™s decision in Mission Prod. Holdings v. Tempnology, LLC, there was a circuit split regarding the licenseeā€™s rights upon the bankruptcy of and rejection by the licensor. Some circuits held that the licenseeā€™s rights terminated upon rejection, while others held that the rights continued. The Supreme Court ultimately resolved these conflicting positions and held that rejection of a trademark license operates as a breach under applicable state law, which allows the licenseeā€™s rights to survive the bankruptcy. While this result seems fair for the licensee who may rely on use of the mark to keep its business afloat, there are certain bankruptcy and trademark issues that may arise such as increased difficulty in reorganization for the licensor, as well as the possibility of naked licensing and abandonment. This Comment explores these potential legal implications, considers legislative amendment, and suggests that practitioners draft contracts accordingly to help manage possible risks created by the Mission decision

    BN Nanotube Serving as a Gas Chemical Sensor for Nā‚‚O by Parallel Electric Field

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    Density functional theory calculations were performed to understand the electronic properties of Cā‚‚ā‚„, Bā‚ā‚‚Nā‚ā‚‚, Bā‚ā‚‚Pā‚ā‚‚, and (6, 0) BNNT interacted with Nā‚‚O molecule in the presence and absence of an external electric field using the B3LYP method and 6-31G** basis set. The adsorption of Nā‚‚O from O-side on the surface of (6, 0) BNNT has high sensitivity in comparison with Bā‚ā‚‚Nā‚ā‚‚ nano-cage. The adsorption energy of Nā‚‚O (O-side) on the sidewalls of Bā‚ā‚‚Nā‚ā‚‚ and BNNT in the presence of an electric field are āˆ’21.01 and āˆ’15.48 kJ molā»Ā¹, respectively. Our results suggest that in the presence of an electric field, the Bā‚ā‚‚Nā‚ā‚‚ nano-cage is the more energetically notable upon the Nā‚‚O adsorption than (6, 0) BNNT, Cā‚‚ā‚„, and Bā‚ā‚‚Pā‚ā‚‚. Whereas, our results indicate that the electronic property of BNNT is more sensitive to Nā‚‚O molecule at the presence of an electric field than Bā‚ā‚‚Nā‚ā‚‚ nano-cage. It is anticipated that BNNT could be a favorable gas sensor for the detection of Nā‚‚O molecule. Ā© 2016, Springer Science+Business Media New York

    Production of protein nanoparticles for food and drug delivery system

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    Ethnopharmacology of Medicinal Plants in the Southwest of Mond Mountain

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    Background: Ethnopharmacology has been seen as a multidisciplinary approach for novel drug discovery by providing valuable data about medicinal plants in different cultures. The aim of this ethnopharmacological study was to identify medicinal plants in the Southwest of Mond Mountain in the North of Persian Gulf. Materials and Methods: The medical uses of medicinal plants were gathered from 20 local informants by face to face interviews. The relative frequency of citation (FRC) and cultural importance (CI) indices were calculated. Results: A total of 116 medicinal plants belonging to 65 families were identified. Zataria multiflora, Achillea eriophora DC, Foeniculum vulgare, Teucrium polium, Haplophyllum tuberculatum, Cuminum cyminum, Plantago psyllium, Nigella sativa and Aleo vera had the highest cultural importance indices. Zataria multiflora, Foeniculum vulgare, Nigella sativa, Cuminum cyminum, and Achillea eriophora DC had the highest FRC indices. The highest medical uses were for gastrointestinal diseases, gynecological diseases, metabolic disorders, respiratory disorders and infectious diseases, respectively. Conclusion: There is a vast variety of medicinal plants in the Southwest of Mond Mountain. Although most of therapeutic applications of these plants in this region are the same as Iranā€™s traditional medicine, but the people in the Southwest of Mond Mountain use some of these plants for some diseases which are unique for this region. For example, the native people of this region used Zataria multiflora, Achillea eriophora DC, Foeniculum vulgare and Haplophyllum tuberculatum for abdominal pain, Nigella sativa for postpartum complications, Aleo vera for hyperlipidemia, Plantago psyllium for drainage of abscesses, Haplophyllum tuberculatum for infectious diseases and muscular pain and Foeniculum vulgare for jaundice.Thus, investigation about these plants should be initiated to discover novel drugs for clinical applications

    Physics of brain dynamics: Fokker-Planck analysis reveals changes in EEG delta-theta interactions in anaesthesia

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    We use drift and diffusion coefficients to reveal interactions between different oscillatory processes underlying a complex signal and apply the method to EEG delta and theta frequencies in the brain. By analysis of data recorded from rats during anaesthesia, we consider the stability and basins of attraction of fixed points in the phase portrait of the deterministic part of the retrieved stochastic process. We show that different classes of dynamics are associated with deep and light anaesthesia, and we demonstrate that the predominant directionality of the interaction is such that theta drives delt

    Aflatoxin contamination in wheat flour samples from Golestan province, Northeast of Iran

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    Background: Due to the high toxicity of aflatoxin and its effects on public health, determination of aflatoxin level in Wheat flour samples in the Golestan province, north of Iran was investigated. To examine the effect of seasonal changes, summer and winter sampling was performed with standard sampling methods. Methods: A total of 200 flour samples were collected from 25 factories. HPLC method with immunoaffinity chromatography was used to measure aflatoxin types (G2, G1, B2 and B1). Statistical analysis was performed by the Pearson correlation test, One-way ANOVA and multivariate regression analysis. Results: Mean total aflatoxin levels of samples were 0.82 and 1.99 ng/g in summer and winter, respectively. Aflatoxin B1 levels were detected in 3.1%, 7.4% over permissible limits by worldwide regulations in samples collected in summer and winter, respectively. Aflatoxins in winter were higher than summer. The highest frequency of aflatoxin contamination in winter was B2 (98%) and in summer G1 (51%). The relationship between humidity and rate of aflatoxin B1 and total aflatoxin was significant in winter. Results of multivariate regression were showed the strongest relationship with humidity and aflatoxin level. Despite the contamination of flour samples, there was no contamination higher than the standard limit of Iran Standard Institute. But it was significantly higher than similar studies from other regions. Conclusions: Therefore, with regard to negative impacts of aflatoxin on health, aflatoxin contamination should be considered in future programs. Decrease of aflatoxin contamination may be made practical through reducing wheat storage duration and controlling humidity

    Development and validation of a metacognitive-cognitive-behavioral model for explaining trichotillomania

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    Background & Aims: Trichotillomania (TTM) is an unknown disorder and resistant to treatment. The purpose of this study was to develop and validate the new metacognitive-cognitive-behavioral model for trichotillomania. Methods: The present study was a description and correlation study. In this study, 635 participants (304 male and 331 female) were selected. The participants completed the Massachusetts general hospital hair pulling scale (MGH-HPS), dysfunctional attitude scale (DAS), cognitive distortion scale (CDS), automatic thought questionnaire (ATQ), metacognition questionnaire (MCQ), and the obsessive-compulsive behavior scale (OCBS). For reliability assessment of the factor structure of the metacognitive-cognitive-behavioral model, the structural equation modeling analysis was used by AMOS software. Results: The results of the structural equation modeling supported a metacognitive-cognitive-behavioral model for trichotillomania. Moreover, the results showed that the model had the best fit to the data and was closely related to the theoretical assumptions. Conclusion: The model presented in this study illustrates a multidimensional approach that focuses on the metacognitive, cognitive, and behavioral dimensions; hence, the model presented in this study is a new explanatory model. This model may prompt future research into trichotillomania and facilitate clinical treatment and case formulation. Ā© 2014, Kerman University of Medical Sciences. All rights reserved

    Motor Responses and Weight Gaining in Neonates through Use of Two Methods of Earmuff and Receiving Silence in NICU

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    Background and Aims. With technological advances in NICUs the survival rate of preterm infants has been increased. Because NICU environment is a potent source of stress for infants, its modification is an essential measure to decrease infantsā€™ morbidity. The purposes of this study were to compare the effects of wearing earmuff and provision silence for infants on their motor responses and gaining weight. Methods. In a randomized clinical trial 96 preterm infants were enrolled. Their motor responses were evaluated for two consecutive days in the morning and afternoon shifts, in the groups of earmuff and silence, and at similar time points in the control group. Also their weight was measured at days 1 and 10. Results. In the two intervention groups, means of motor responses in infants were significantly less than in the control group, and weight gain of infants was more than the control group. However weight gain was more pronounced in the earmuff group. Conclusion. Both interventions led to decreasing number of motor responses and improvement of weight gain pattern, but these effects were more pronounced in earmuff group; thus because implementation of silence in NICUs has many barriers, it is suggested to use earmuff for preterm infants in these units. This trial obtained IRCT registration number IRCT2012092010812N2

    Transvaginal sonographic evaluation at different menstrual cycle phases in diagnosis of uterine lesions

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    Masomeh Hajishaiha1, Mohammad Ghasemi-rad2, Nazila Karimpour1, Nikol Mladkova3, Farzaneh Boromand11Department of Gynecology, 2Student Research Committee (SRC), Urmia University of Medical Sciences, Urmia, Islamic Republic of Iran; 3Institute of Cell and Molecular Science, London, UKPurpose: Intrauterine lesions (IULs) are a common finding in women of reproductive age, particularly infertile women. Transvaginal sonography (TVS) is a popular tool for IUL detection, but there are conflicting data with respect to its accuracy.Methods: Five hundred and six women were enrolled into the study. Of these, 496 underwent hysterosalpingography and subsequent TVS six different times during the course of their menstrual cycle. If a lesion was detected, it was further evaluated by sonohysterography (SHG) and hysteroscopy.Results: Of 496 women, 41 were shown to have IULs by TVS and those lesions were confirmed in 39 by SHG and hysteroscopy. All 39 lesions were detectable during the ovulatory and early luteal phase (days 16–19) of the menstrual cycle. Accuracy of TVS during different phases was largely dependent on the size of the lesion. TVS falsely detected two lesions and missed fine adhesions in two patients.Conclusion: Accuracy of TVS in detection of IULs is highly dependent on the menstrual cycle phase, with the ovulatory and early luteal phase being the optimal time for this examination.Keywords: menstrual cycle phase, space occupying lesions, transvaginal sonograph
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