17 research outputs found
Digestible lysine levels obtained by two methods of formulation of diets for 22-to-42-day-old broilers
A study of hydraulic fracturing clean-up efficiency in unconventional gas reservoirs using statistical approaches
Hydraulic fracturing is widely used to improve well productivity especially in unconventional reservoirs. This costly operation, however, sometimes underperforms. One of the main reasons for this poor performance is poor clean-up efficiency of injected fracturing fluid (FF). In this work, a parametric study of FF clean-up efficiency of hydraulic fractured vertical wells was performed with 49152 simulations (in 12 sets) consisting of injection, soaking and production periods. Due to the large number of required simulations, that were conducted using a commercial reservoir simulator, a developed computer code was used to automatically read input data, run simulations and creates output data. In each set (consisting of 4096 runs), simultaneous impacts of 12 parameters (fracture permeability, matrix permeability and capillary pressure, end points and exponents of Corey gas and FF relative permeability curve in both matrix and fracture) were studied. To sample the variables domain and analyse results, two-level full factorial experimental design and linear surface model describing dependency of gas production loss (GPL), compared to 100 clean-up, to pertinent parameters at three production periods (10, 30 and 365 days) were considered and supported by the tornado charts of fitted equations, frequency of simulations with given GPL and FF saturation maps. Results indicate that generally parameters controlling FF mobility within fracture had greatest impact on GPL reduction. However in sets with very low matrix permeability especially when applied pressure drop during production is low, the effect of fluid mobility in the matrix on GPL is more pronounced, in other words, it is important how gas and FF flow within matrix rather than how fast fracture is cleaned. In tighter gas formations, generally more GPL and slower clean-up was observed. The effect of matrix capillary pressure on GPL reduction was more pronounced when drawdown was very low and/or soaking time was extended. This observation was more profound in tighter formations, i.e. for these formations, the effect of a change in drawdown and/or soaking time on matrix capillary pressure and GPL was more pronounced. These findings can be used to make better decisions on the performance and optimised design of hydraulic fracturing, which is a costly but widely used stimulation technique for unconventional low permeability gas reservoirs
A study of hydraulic fracturing clean-up efficiency in unconventional gas reservoirs using statistical approaches
Nonlinear Properties of III-V Semiconductor Nanowaveguides
Nonlinear optics (NLO) plays a major role in the modern world: nonlinear optical phenomena have been observed in a wavelength range going from the deep infrared to the extreme ultraviolet, to THz radiation. The optical nonlinearities can be found in crystals, amorphous materials, polymers, liquid crystals, liquids, organic materials, and even gases and plasmas. Nowadays, NLO is relevant for applications in quantum optics, quantum computing, ultra-cold atom physics, plasma physics, and particle accelerators. The work presented in the thesis is limited only to the semiconductors that have a second-order optical nonlinearity and includes two phenomena that use second-order nonlinearity: second-harmonic generation (SHG) and spontaneous parametric down-conversion (SPDC). Among the many options available, the investigation presented concerns gallium phosphide (GaP) and gallium indium phosphide (Ga0.51In0.49P), two semiconductors of the group III-V with the ¯43m crystal symmetry. However, some of the results found can be generalized for other materials with ¯43m crystal symmetry. In the thesis, the fabrication of GaP nanowaveguides with dimensions from 0.03 μm and an aspect ratio above 20 using focused ion beam (FIB) milling is discussed. The problem of the formation of gallium droplets on the surface is solved by using a pulsed laser to oxidize the excess surface gallium locally on the FIB-milled nanowaveguides. SHG is used to evaluate the optical quality of the fabricated GaP nanowaveguides. Additionally, a theoretical and experimental way to enhance SHG in nanowaveguides is introduced. This process uses the overlap of interacting fields defined by the fundamental mode of the pump and the second-order mode of the SHG, which is enhanced by the longitudinal component of the nonlinear polarization density. Through this method, it was possible to obtain a maximum efficiency of 10−4, which corresponds to 50 W−1cm−2. The method can be generalized for any material with a ¯43m crystal symmetry. Furthermore, SHG is used to characterize the nonlinear properties of a nanostructure exposed for a long time to a CW laser at 405 nm to reduce the photoluminescence (PL) of Ga0.51In0.49P. The PL was reduced by -34 dB without causing any damage to the nanostructures or modifying the nonlinear properties. The fabrication process for obtaining the nanowaveguide is interesting as well, since the fabricated waveguide in Ga0.51In0.49P, whose sizes are 200 nm thick, 11 μm wide and 1.5 mm long, was transferred on silicon dioxide (SiO2). This type of nanowaveguide is interesting for SPDC, since it satisfies the long interaction length necessary for an efficient SPDC. Finally, a configuration consisting of illuminating the top surface of a nanowaveguide with a pump beam to generate signal and idler by SPDC is presented. These fabricated nanostructures open a way to the generation of counter-propagating idler and signal with orthogonal polarization. By using a different cut of the crystal, i.e. [110], it makes possible to obtain degenerate wavelength generation, and in certain conditions to obtain polarization-entangled photons or squeezed states
Electric-driven membrane poration. A rationale for water role in the kinetics of pore formation
Electroporation is a well-established technique used to stimulate cells, enhancing membrane permeability by inducing reversible membrane pores. In the absence of experimental observation of the dynamics of pore creation, molecular dynamics studies provide the molecular-level evidence that the electric field promotes pore formation. Although single steps in the pore formation process are well assessed, a kinetic model representing the mathematical description of the electroporation process, is lacking. In the present work we studied the basis of the pore formation process, providing a rationale for the definition of a first-order kinetic scheme. Here, authors propose a three-state kinetic model for the process based on the assessed mechanism of water defects intruding at the water/lipid interface, when applying electric field intensities at the edge of the linear regime. The methodology proposed is based on the use of two robust biophysical quantities analyzed for the water molecules intruding at the water/lipid interface: (i) number of hydrogen bonds; (ii) number of contacts. The final model, sustained by a robust statistical sampling, provides kinetic constants for the transitions from the intact bilayer state to the hydrophobic pore state
Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part II: Chicken and turkey
Physiologically based pharmacokinetic (PBPK) models are growing in popularity due to human food safety concerns and for estimating drug residue distribution and estimating withdrawal intervals for veterinary products originating from livestock species. This paper focuses on the physiological and anatomical data, including cardiac output, organ weight, and blood flow values, needed for PBPK modeling applications for avian species commonly consumed in the poultry market. Experimental and field studies from 1940 to 2019 for broiler chickens (1-70 days old, 40 g - 3.2 kg), laying hens (4-15 months old, 1.1-2.0 kg), and turkeys (1 day-14 months old, 60 g -12.7 kg) were searched systematically using PubMed, Google Scholar, ProQuest, and ScienceDirect for data collection in 2019 and 2020. Relevant data were extracted from the literature with mean and standard deviation (SD) being calculated and compiled in tables of relative organ weights (% of body weight) and relative blood flows (% of cardiac output). Trends of organ or tissue weight growth during different life stages were calculated when sufficient data were available. These compiled data sets facilitate future PBPK model development and applications, especially in estimating chemical residue concentrations in edible tissues to calculate food safety withdrawal intervals for poultry